Zobrazeno 1 - 10
of 452
pro vyhledávání: '"SUSUMU ITOH"'
Autor:
Masashiro Sugino, Toru Kuboi, Yuta Noguchi, Katsufumi Nishioka, Yoko Tadatomo, Nana Kawaguchi, Takaaki Sadamura, Akiko Nakano, Yukihiko Konishi, Kosuke Koyano, Shinji Nakamura, Hitoshi Okada, Susumu Itoh, Takashi Kusaka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Therapeutic drug monitoring is generally unnecessary in caffeine treatment for apnea of prematurity, as serum caffeine concentrations in preterm infants are normally markedly lower than those at which caffeine intoxication occurs. However, s
Externí odkaz:
https://doaj.org/article/fccec56558ff429abf1216a259d73149
Autor:
Susumu Itoh, Hitoshi Okada, Kosuke Koyano, Shinji Nakamura, Yukihiko Konishi, Takashi Iwase, Takashi Kusaka
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2023)
Human fetal and neonatal bilirubin metabolism is centered on 4Z,15Z-bilirubin IXα (BR) due to the extremely low BR conjugating capacity of the liver. BR is a unique, highly lipophilic substance with physiological and toxic effects in the cell membra
Externí odkaz:
https://doaj.org/article/e5109605a1104be0b7e930a96ef05f0d
Autor:
Kunpei Fukasawa, Kako Hanada, Kei Ichikawa, Masanori Hirashima, Takahiro Takagi, Susumu Itoh, Testuro Watabe, Fumiko Itoh
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-11 (2021)
Abstract Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis. Although TGF-β signaling is essential for maintaining blood vessel functions, little
Externí odkaz:
https://doaj.org/article/f1dce799d34944ca932abddf07f07cd3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Phototherapy using light-emitting diodes (LEDs) centered on the green spectrum, which has a high cyclobilirubin production rate, was as effective as that centered on the blue spectrum for neonatal hyperbilirubinemia. There are no reports of
Externí odkaz:
https://doaj.org/article/199a68d7149942b0b28fce7cec2666e0
Autor:
Rie Kawamoto, Naoko Nakano, Haruka Ishikawa, Etsu Tashiro, Waka Nagano, Keigo Sano, Miki Irie, Mariko Ikuta, Fukuko Kishi, Takahisa Nakane, Mikihiko Naito, Susumu Itoh
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100008- (2021)
Yes-associated protein (YAP) is involved in development, cell growth, cell size, and homeostasis and plays a key role in the progression of various cancers. Among them, constitutive activation of YAP can often be observed in malignant mesothelioma, w
Externí odkaz:
https://doaj.org/article/b631388b21c244839b8427702452f753
Autor:
Noopur Thakur, Anahita Hamidi, Jie Song, Susumu Itoh, Anders Bergh, Carl-Henrik Heldin, Maréne Landström
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101470- (2020)
Summary: Transforming growth factor β (TGF-β) enhances migration and invasion of cancer cells, causing life-threatening metastasis. Smad7 expression is induced by TGF-β to control TGF-β signaling in a negative feedback manner. Here we report an a
Externí odkaz:
https://doaj.org/article/66dc3313eb444b5e9c5d9f570a4b9540
Autor:
Makoto Arioka, Kosuke Koyano, Yasuhiro Nakao, Miyo Ozaki, Shinji Nakamura, Hiroyuki Kiuchi, Hitoshi Okada, Susumu Itoh, Koji Murao, Takashi Kusaka
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 60:177-183
Background Exposing blood serum samples to ambient white light-emitting diode (WLED) light may accelerate bilirubin photoisomer production. We previously demonstrated the quantitative effect of bilirubin configurational isomers (BCI) on direct biliru
Publikováno v:
Oncology Research; 2024, Vol. 32 Issue 1, p139-150, 12p
Autor:
Naoko Nakano, Kazuo Fukuda, Etsu Tashiro, Haruka Ishikawa, Waka Nagano, Rie Kawamoto, Alice Mori, Misao Watanabe, Ryu Yamazaki, Takahisa Nakane, Mikihiko Naito, Iwao Okamoto, Susumu Itoh
Publikováno v:
The Journal of Biochemistry. 171:631-640
Dysregulated yes-associated protein (YAP) is involved in several malignant cancers. However, discovering a druggable YAP inhibitor(s) is difficult because YAP itself does not have any enzymatic activity. In such cases, targeted protein degradation st
Autor:
Hibiki Yamamoto, Diego Fujii, Yasuyo Kita, Ichiro Matsuda, Susumu Itoh, Kyohei Unno, Satoshi Komorita
Publikováno v:
International Workshop on Advanced Imaging Technology (IWAIT) 2023.