Zobrazeno 1 - 10
of 53
pro vyhledávání: '"SURINDER K. AGGARWAL"'
Publikováno v:
Journal of Histochemistry & Cytochemistry. 47:1057-1062
Cisplatin treatment (9 mg/kg) causes bloating of the stomach, an increase in gastric acid, and ulceration in rats. Gastrin, a gut peptide, plays an important role in regulating gastric acid production. To study the role of gastrin in this increased g
Autor:
Surinder K. Aggarwal
Publikováno v:
Metal-Based Drugs
Cisplatin (CDDP) is a potent anti-neoplastic agent with associated toxicities, especially gastrointestinal and nephrotoxicity that are its dose-limiting factors in clinical oncology. In an attempt to elucidate its mechanism(s) of action, liver and ki
Publikováno v:
Anti-Cancer Drugs. 9:93-99
Swiss Webster mice treated with bolus injections of 'poly-plat' (10 mg/kg) show increased macrophage activation after 2 and 12 days when isolated in cultures. Such macrophages demonstrate an increase in the number of lysosomes and cytoplasmic extensi
Publikováno v:
Anti-Cancer Drugs. 8:784-789
Cisplatin and paclitaxel are potent antineoplastic agents. Their distinctly different mechanisms of action have prompted laboratory and clinical research into their use in combination therapies. Murine peritoneal macrophages treated with cisplatin an
Autor:
Surinder K. Aggarwal, JoAnn P Palma
Publikováno v:
Anti-Cancer Drugs. 5:615-622
The anticancer drugs cisplatin and carboplatin have been shown to activate murine peritoneal macrophages in vivo and in vitro. These activated macrophages have enhanced tumoricidal activity mediated by extension and contact formation with the tumor c
Autor:
James M. Fadool, Surinder K. Aggarwal
Publikováno v:
Anti-Cancer Drugs. 4:149-162
Cytochemical and ultrastructural studies in Wistar rats [Crl: (WI)BR] show that cisplatin treatment (5-9 mg/kg) induces a release of neurosecretory granules from the neurohypophysis with a corresponding decrease in the urine output in a time and dose
Publikováno v:
Emerging Therapeutic Targets. 1:155-157
Publikováno v:
Anticancer research. 22(4)
Action of Cisplatin (cis-dichlorodiammine platinum II) and Poly-Plat [poly-[(trans-1,2-diaminocyclohexane) pla-tinum]-carboxyamylose] on tumor cells was examined using human fibrosarcoma (HT1080) and Walker rat carcinoma (WRC-256) in culture. These c
Publikováno v:
Metal-Based Drugs
In rats cisplatin induces hypocalcemia, bloating of the stomach, and ulceration ameliorated through calcium supplements. This study was undertaken to test the role of calcium on the gastrin mRNA production in vitro and in vivo. RIN B6 cells were cult
Publikováno v:
Metal-Based Drugs