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pro vyhledávání: '"SURENDRA BODAKHE"'
Autor:
SURENDRA BODAKHE, Dr. Amrita Singh
Publikováno v:
British Journal of Pharmacology. 179:4673-4691
A high-fat diet (HFD) is a common risk factor for Type 2 diabetes mellitus (T2DM) and its associated cognitive impairments. In models of diabetes, resveratrol, a modulator of SIRT1, regulates the fasting glucose and antioxidant levels, as well as the
Publikováno v:
Current Eye Research. 46:52-63
High glucose level is a strong initiator of both oxidative stress and DNA damage to various cellular proteins. This activates the poly ADP-ribose polymerase (PARP) enzyme, which is responsible for disturbing physiological energy metabolic homeostasis
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 34
Oxidative stress-induced toxicity plays a major role in ocular diseases such as retinal degeneration, age-related cataract (ARC) formation and macular dystrophy. In this study, we explored the possible role of resveratrol (RSV) at the different dose
Publikováno v:
Life sciences. 167
Aims Previously we found that cadmium chloride (CdCl 2 ) exposure substantially elevates hypertension and potentiates cataract formation. In the present study, we investigated the protective effects of olmesartan, an angiotensin II receptor blocker a