Zobrazeno 1 - 10
of 81
pro vyhledávání: '"SUPING REN"'
Autor:
Ezhilpavai Mohanan, Guofang Shen, Suping Ren, Hsuan‐Hao Fan, Kao Tang Ying Moua, Aleksandra Karolak, Russell C. Rockne, Ryotaro Nakamura, David A. Horne, Christopher G. Kanakry, Donald E. Mager, Jeannine S. McCune
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Dose optimization of sirolimus may further improve outcomes in allogeneic hematopoietic cell transplant (HCT) patients receiving post‐transplantation cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD). Sirolimus exposu
Externí odkaz:
https://doaj.org/article/1ad61f5066c845a0a3e42d38aae318d1
Autor:
Jeannine S. McCune, Sandi L. Navarro, Linda J. Risler, Brian R. Phillips, Suping Ren, H. Gary Schoch, K. Scott Baker
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2577-2590 (2023)
Abstract Busulfan is hepatically metabolized through glutathione (GSH) conjugation; in vitro, this process depletes hepatocyte GSH stores and generates the cytotoxic metabolite γ‐glutamyldehydroalanylglycine, which is too unstable to be quantitate
Externí odkaz:
https://doaj.org/article/ceb3802b92a543fb95917bf8b6076114
Autor:
Wei Shen, Suping Ren, Yongyong Hou, Zhuo Zuo, Shengnan Liu, Zhiyuan Liu, Jingqi Fu, Huihui Wang, Bei Yang, Rui Zhao, Yanyan Chen, Masayuki Yamamoto, Yuanyuan Xu, Qiang Zhang, Jingbo Pi
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102879- (2023)
Brown adipose tissue (BAT) is a major site of non-shivering thermogenesis in mammals and plays an important role in energy homeostasis. Nuclear factor-erythroid 2-related factor 1 (NFE2L1, also known as Nrf1), a master regulator of cellular metabolic
Externí odkaz:
https://doaj.org/article/9c1c7c7cf9344c72b1e3497fdac47bba
Autor:
Andreas Jekle, Santosh Kumar Thatikonda, Ruchika Jaisinghani, Suping Ren, April Kinkade, Sarah K. Stevens, Antitsa Stoycheva, Vivek K. Rajwanshi, Caroline Williams, Jerome Deval, Sucheta Mukherjee, Qingling Zhang, Sushmita Chanda, David B. Smith, Lawrence M. Blatt, Julian A. Symons, Francois Gonzalvez, Leonid Beigelman
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16274 (2023)
Stimulator of interferon genes (STING) agonists have shown potent anti-tumor efficacy in various mouse tumor models and have the potential to overcome resistance to immune checkpoint inhibitors (ICI) by linking the innate and acquired immune systems.
Externí odkaz:
https://doaj.org/article/512c73ca5afc43cb8be9c4e5e591a5b8
Autor:
C. Cheng Kao, Yuchun Nie, Suping Ren, N. Tilani T.S. De Costa, Rajendra K. Pandey, Jin Hong, David B. Smith, Julian A. Symons, Leonid Beigelman, Lawrence M. Blatt
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 335-348 (2022)
A functional cure of chronic hepatitis B requires eliminating the hepatitis B virus (HBV)-encoded surface antigen (HBsAg), which can suppress immune responses. STOPS are phosphorothioated single-stranded oligonucleotides containing novel chemistries
Externí odkaz:
https://doaj.org/article/3009f7da2edc4ff9b9530dca559fa931
Autor:
Zhiyuan Liu, Huihui Wang, Yongyong Hou, Yang Yang, Jingkun Jia, Jinzhi Wu, Zhuo Zuo, Tianchang Gao, Suping Ren, Yiying Bian, Shengnan Liu, Jingqi Fu, Yongxin Sun, Jiliang Li, Masayuki Yamamoto, Qiang Zhang, Yuanyuan Xu, Jingbo Pi
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102180- (2021)
Fine-tuning of osteoclast differentiation (OD) and bone remodeling is crucial for bone homeostasis. Dissecting the mechanisms regulating osteoclastogenesis is fundamental to understanding the pathogenesis of various bone disorders including osteoporo
Externí odkaz:
https://doaj.org/article/12524d37aec54ad8b4d35691e0ff0702
Autor:
Suping Ren, Yiying Bian, Yongyong Hou, Zhendi Wang, Zhuo Zuo, Zhiyuan Liu, Yue Teng, Jingqi Fu, Huihui Wang, Yuanyuan Xu, Qiang Zhang, Yanyan Chen, Jingbo Pi
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 102015- (2021)
Adipocytes play pivotal roles in maintaining energy homeostasis by storing lipids in adipose tissue (AT), regulating the flux of lipids between AT and the circulation in response to the body's energy requirements and secreting a variety of hormones,
Externí odkaz:
https://doaj.org/article/efef17bc8c1f438e85a8f71e56dda0ba
Autor:
Peng Xue, Yongyong Hou, Zhuo Zuo, Zhendi Wang, Suping Ren, Jian Dong, Jingqi Fu, Huihui Wang, Melvin E. Andersen, Qiang Zhang, Yuanyuan Xu, Jingbo Pi
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Nuclear factor erythroid 2-related factor 1 (NRF1), a ubiquitously expressed CNC-bZIP transcription factor, plays a critical role in white adipocyte (WAC) biology, whereas the underlying mechanisms remain unknown. The mouse Nrf1 gene is transcribed i
Externí odkaz:
https://doaj.org/article/a812b2ba731142918a5e1c80f17005f1
Autor:
Mu He, Zhixin Qiao, Yanbing Wang, Qiyuan Kuai, Changlan Li, Yu Wang, Xingwei Jiang, Xuanlin Wang, Weijing Li, Min He, Suping Ren, Qun Yu
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166896 (2016)
Pancreatic cancer is a fatal malignancy worldwide and urgently requires valid therapies. Previous research showed that the HDAC inhibitor chidamide is a promising anti-cancer agent in pancreatic cancer cell lines. In this study, we elucidate a probab
Externí odkaz:
https://doaj.org/article/ceed9e24111c4ce3b2a724bb0002d852
Autor:
Suping Ren, Lina Chai, Chunyan Wang, Changlan Li, Qiquan Ren, Lihua Yang, Fumei Wang, Zhixin Qiao, Weijing Li, Min He, Adam I Riker, Ying Han, Qun Yu
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119038 (2015)
Progestagen-associated endometrial protein (PAEP) is a glycoprotein of the lipocalin family that acts as a negative regulator of T cell receptor-mediated activation. However, the function of tumor-derived PAEP on the human immune system in the tumor
Externí odkaz:
https://doaj.org/article/17481b536d354cdcb4d05214a0a03916