Zobrazeno 1 - 10
of 686
pro vyhledávání: '"SUNG-JIN LEE"'
Publikováno v:
Toxins, Vol 16, Iss 10, p 436 (2024)
Gossypol (GP), a polyphenolic compound in cottonseed, has notable effects on female reproduction and the respiratory system in pigs. This study aimed to discern the alterations in gene expression within swine granulosa cells (GCs) when treated with t
Externí odkaz:
https://doaj.org/article/404df4c024ae4b50942e603ccfad62bd
Autor:
Parthasarathy Sampathkumar, Heekyung Jung, Hui Chen, Zhengjian Zhang, Nicholas Suen, Yiran Yang, Zhong Huang, Tom Lopez, Robert Benisch, Sung-Jin Lee, Jay Ye, Wen-Chen Yeh, Yang Li
Publikováno v:
eLife, Vol 13 (2024)
Molecules that facilitate targeted protein degradation (TPD) offer great promise as novel therapeutics. The human hepatic lectin asialoglycoprotein receptor (ASGR) is selectively expressed on hepatocytes. We have previously engineered an anti-ASGR1 a
Externí odkaz:
https://doaj.org/article/a9f6fd6b3417451d9b40177a6d13884a
Autor:
Yorick Post, Chenggang Lu, Russell B. Fletcher, Wen-Chen Yeh, Huy Nguyen, Sung-Jin Lee, Yang Li
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109938- (2024)
Summary: Wingless-related integration site or Wingless and Int-1 or Wingless-Int (WNT) signaling is crucial for embryonic development, and adult tissue homeostasis and regeneration, through its essential roles in cell fate, patterning, and stem cell
Externí odkaz:
https://doaj.org/article/51fbdba0cc7644558da5ecd67f417121
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Pick-and-place is essential in diverse robotic applications for industries including manufacturing, and assembly. Soft grippers offer a cost-effective, and low-maintenance alternative for secure object grasping without complex sensing and co
Externí odkaz:
https://doaj.org/article/451d2bb784684f59aad3a8d0ed0166ae
Autor:
Hui Chen, Sung-Jin Lee, Ryan Li, Asmiti Sura, Nicholas Suen, Archana Dilip, Yan Pomogov, Meghah Vuppalapaty, Timothy T Suen, Chenggang Lu, Yorick Post, Yang Li
Publikováno v:
eLife, Vol 12 (2024)
Systemic toxicity is a major challenge in the development of therapeutics. Consequently, cell-type-specific targeting is needed to improve on-target efficacy while reducing off-target toxicity. Here, we describe a cell-targeting system we have termed
Externí odkaz:
https://doaj.org/article/b18a4fedb9594fe39bd8ab03b0fe2af9
Autor:
Jie Ding, Sung-Jin Lee, Lukas Vlahos, Kanako Yuki, Cara C. Rada, Vincent van Unen, Meghah Vuppalapaty, Hui Chen, Asmiti Sura, Aaron K. McCormick, Madeline Tomaske, Samira Alwahabi, Huy Nguyen, William Nowatzke, Lily Kim, Lisa Kelly, Douglas Vollrath, Andrea Califano, Wen-Chen Yeh, Yang Li, Calvin J. Kuo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and Alzheimer’s disease. The Norrin/FZD4/TSPAN12 pathway activates WNT/β-catenin signaling,
Externí odkaz:
https://doaj.org/article/31df630cc0d74d1eb51da2d91c5e7f3c
Autor:
Syahira Izyana Mohd Azmi, Pavan Kumar, Neelesh Sharma, Awis Qurni Sazili, Sung-Jin Lee, Mohammad Rashedi Ismail-Fitry
Publikováno v:
Foods, Vol 13, Iss 3, p 379 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/68bd2d0428ce4791bcf111b421051876
Autor:
Pavan Kumar, Neelesh Sharma, Muideen Adewale Ahmed, Akhilesh K. Verma, Pramila Umaraw, Nitin Mehta, Ahmed Abubakar Abubakar, Muhammad Nizam Hayat, Ubedullah Kaka, Sung-Jin Lee, Awis Qurni Sazili
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Meat analogs have opened a new horizon of opportunities for developing a sustainable alternative for meat and meat products. Proteins are an integral part of meat analogs and their functionalities have been extensively studied to mimic meat-like appe
Externí odkaz:
https://doaj.org/article/50b83571e98244cb84769bfebef64ce0
Autor:
Tristan W. Fowler, Troy L. Mitchell, Claudia Y. Janda, Liqin Xie, Shengjiang Tu, Hui Chen, Haili Zhang, Jingjing Ye, Brian Ouyang, Tom Z. Yuan, Sung-Jin Lee, Maureen Newman, Nikita Tripuraneni, Erica S. Rego, Devin Mutha, Archana Dilip, Meghah Vuppalapaty, Helene Baribault, Wen-Chen Yeh, Yang Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Antibody-based Wnt agonists are able to phenocopy Wnt signaling in vivo resulting in increased bone density, repair, and strength. Here, the authors show that Wnt agonists can reverse bone loss associated with ovariectomy and build stronger bone when
Externí odkaz:
https://doaj.org/article/f832347476cc4872864883076749da99
Publikováno v:
Applied Sciences, Vol 13, Iss 7, p 4598 (2023)
Occupational safety and health is among the most challenging issues in many industrial workplaces, in that various factors can cause occupational illness and injury. Robotics, automation, and other state-of-the-art technologies represent risks that c
Externí odkaz:
https://doaj.org/article/bb2524654de640c4b4a6c553cb40ab90