Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation.

Autor: Liu JCY; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Ackermann L; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Hoffmann S; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Gál Z; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Hendriks IA; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Jain C; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Morlot L; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Tatham MH; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, UK., McLelland GL; Division of Biochemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Hay RT; Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, UK., Nielsen ML; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Brummelkamp T; Division of Biochemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Haahr P; Division of Biochemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands. peter.haahr@sund.ku.dk.; Department of Cellular and Molecular Medicine, Center for Gene Expression, University of Copenhagen, Copenhagen, Denmark. peter.haahr@sund.ku.dk., Mailand N; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark. niels.mailand@cpr.ku.dk.; Department of Cellular and Molecular Medicine, Center for Chromosome Stability, University of Copenhagen, Copenhagen, Denmark. niels.mailand@cpr.ku.dk.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Sep; Vol. 31 (9), pp. 1355-1367. Date of Electronic Publication: 2024 Apr 22.

Guanosine increases global SUMO1-ylation in the hippocampus of young and aged mice and improves the short-term memory of young mice.

Autor: Zanella CA; Pharmacology Department, Pharmacology Postgraduate Program, Biological Sciences Center (CCB), Federal University of Santa Catarina (UFSC), Florianópolis, Brazil., Marques N; Biochemistry Department, Biochemistry Postgraduate Program, CCB, UFSC, Florianópolis, Brazil., Junqueira S; Neuroscience Postgraduate Program, CCB, UFSC, Florianópolis, Brazil., Prediger RD; Pharmacology Department, Pharmacology Postgraduate Program, Biological Sciences Center (CCB), Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.; Neuroscience Postgraduate Program, CCB, UFSC, Florianópolis, Brazil., Tasca CI; Biochemistry Department, Biochemistry Postgraduate Program, CCB, UFSC, Florianópolis, Brazil.; Neuroscience Postgraduate Program, CCB, UFSC, Florianópolis, Brazil., Cimarosti HI; Pharmacology Department, Pharmacology Postgraduate Program, Biological Sciences Center (CCB), Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.; Neuroscience Postgraduate Program, CCB, UFSC, Florianópolis, Brazil.

Publikováno v: Journal of neurochemistry [J Neurochem] 2024 Aug; Vol. 168 (8), pp. 1503-1513. Date of Electronic Publication: 2023 Jul 25.

Stepwise phosphorylation and SUMOylation of PIDD1 drive PIDDosome assembly in response to DNA repair failure.

Autor: Shah RB; Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Cell, Developmental and Regenerative Biology, The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Li Y; Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Cell, Developmental and Regenerative Biology, The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Yu H; Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Cell, Developmental and Regenerative Biology, The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kini E; Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Cell, Developmental and Regenerative Biology, The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sidi S; Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. samuel.sidi@mssm.edu.; Department of Cell, Developmental and Regenerative Biology, The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. samuel.sidi@mssm.edu.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. samuel.sidi@mssm.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 24; Vol. 15 (1), pp. 9195. Date of Electronic Publication: 2024 Oct 24.

Novel Collagen Analogs with Multicopy Mucin-Type Sequences for Multifunctional Enhancement Properties Using SUMO Fusion Tags.

Autor: Zhao Z; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710127, China., Yuwen W; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710127, China., Duan Z; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710127, China., Zhu C; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710127, China., Fan D; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710127, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710127, China.

Publikováno v: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Oct 09; Vol. 72 (40), pp. 22173-22185. Date of Electronic Publication: 2024 Sep 25.

SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus.

Autor: Song CC; Hubei Hongshan Laboratory, Fishery College, Huazhong Agriculture University, Wuhan, 430070, China., Liu T; Hubei Hongshan Laboratory, Fishery College, Huazhong Agriculture University, Wuhan, 430070, China., Hogstrand C; Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, UK., Zhong CC; Hubei Hongshan Laboratory, Fishery College, Huazhong Agriculture University, Wuhan, 430070, China., Zheng H; Hubei Hongshan Laboratory, Fishery College, Huazhong Agriculture University, Wuhan, 430070, China., Sun LH; State Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, 430070, China., Luo Z; Hubei Hongshan Laboratory, Fishery College, Huazhong Agriculture University, Wuhan, 430070, China. luozhi99@mail.hzau.edu.cn.; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China. luozhi99@mail.hzau.edu.cn.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Oct 05; Vol. 81 (1), pp. 422. Date of Electronic Publication: 2024 Oct 05.