Zobrazeno 1 - 10
of 4 586
pro vyhledávání: '"SUMO protein"'
Publikováno v:
Journal of Integrative Neuroscience, Vol 20, Iss 3, Pp 595-603 (2021)
Collapsin response mediator protein 4 (CRMP4) is critical for neuronal development. However, whether CRMP4 could be SUMOylated and how the SUMOylation regulates the interaction with the L-type voltage-gated calcium channel (Cav1.2), neurite outgrowth
Externí odkaz:
https://doaj.org/article/a592f4154c864dc2b7ce1ae7ec89a3ad
Publikováno v:
Seminars in Cell & Developmental Biology. 132:193-202
Post-translational modification by Small Ubiquitin-like Modifier (SUMO) proteins regulates numerous cellular processes. This modification involves the covalent and reversible attachment of SUMO to target proteins through an isopeptide bond, using a c
Autor:
Atheer Awad Mehde, Faridah Yusof, Wesen Adel Mehdi, Raha Ahmed Raus, Layla Othman Farhan, Jwan Abdulmohsin Zainulabdeen, Zaima Azira Zainal Abidin, Hamid Ghazali, Azlina Abd Rahman
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 3, Pp 249-252 (2017)
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunt
Externí odkaz:
https://doaj.org/article/2fd3a11a150945b483daef2965532219
Autor:
Jing Liang, Lin Chen
Publikováno v:
Process Biochemistry. 112:1-5
Protein SUMOylation is a kind of post-translational modification that closely involves numerous physiological and pathological processes. Because of the important role of SUMOylation in living cells, sensitivity characterization of SUMOylation is urg
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss, Pp 355-366 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Based on our initial bioinformatics finding of the upregulated expression of sentrin-specific protease 1 (SENP1) and cyclin E1 (CCNE1) in Wilms tumor, this study aimed to illustrate the molecular mechanism of SENP1 in Wilms tumor, which involved the
Autor:
Nalini Dhingra, Xiaolan Zhao
Publikováno v:
Curr Opin Genet Dev
Homologous Recombination (HR) is a critical DNA repair mechanism for a range of genome lesions. HR is responsible for mending DNA double strand breaks (DSBs) using intact template DNA. In addition, many HR proteins help cope with DNA lesions generate
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of Neural Transmission. 129:463-475
Ubiquitination and sumoylation are two important posttranslational modifications in cells. RING (Really Interesting New Gene)-type E3 ligases play essential roles in regulating a plethora of biological processes such as cell survival and death. In ou
Autor:
Jianxiu Yu, Yishu Wang
Publikováno v:
Cancer Letters. 521:88-97
Protein modification with small ubiquitin-like modifiers (SUMOs) plays dual roles in prostate cancer (PCa) tumorigenesis and development. Any intermediary of the SUMO conjugation cycle going awry may forfeit the balance between tumorigenic potential
Publikováno v:
Experimental and Molecular Medicine, Vol 53, Iss 11, Pp 1683-1688 (2021)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Crosstalk between post-translational modifications of histone proteins influences the regulation of chromatin structure and gene expression. Among such crosstalk pathways, the best-characterized example is H2B monoubiquitination-mediated H3K4 and H3K