Zobrazeno 1 - 10
of 191
pro vyhledávání: '"SUMAN JAIN"'
Autor:
Pragya Gupta, Sangam Giri Goswami, Geeta Kumari, Vinodh Saravanakumar, Nupur Bhargava, Akhila Balakrishna Rai, Praveen Singh, Rahul C. Bhoyar, V. R. Arvinden, Padma Gunda, Suman Jain, Vanya Kadla Narayana, Sayali C. Deolankar, T. S. Keshava Prasad, Vivek T. Natarajan, Vinod Scaria, Shailja Singh, Sivaprakash Ramalingam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ex vivo cellular system that accurately replicates sickle cell disease and β-thalassemia characteristics is a highly sought-after goal in the field of erythroid biology. In this study, we present the generation of erythroid progenitor lines
Externí odkaz:
https://doaj.org/article/057cee76498e45b68c0e7b95f3a332c8
Autor:
Rajneesh Prajapat, Suman Jain
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 9, Iss 3, Pp 143-153 (2023)
Background & Aims: The active site of RdRp-CoV is highly conserved, with two successive and surface-accessible aspartates in a beta-turn structure. Antiviral drugs Remdesivir, Galidesivir, Tenofovir, Sofosbuvir, and Ribavirin are known as inhibitors
Externí odkaz:
https://doaj.org/article/d19e67b51bca4437ab7f7e8996220ebd
Autor:
Pragya Gupta, V. R. Arvinden, Priya Thakur, Rahul C. Bhoyar, Vinodh Saravanakumar, Narendra Varma Gottumukkala, Sangam Giri Goswami, Mehwish Nafiz, Aditya Ramdas Iyer, Harie Vignesh, Rajat Soni, Nupur Bhargava, Padma Gunda, Suman Jain, Vivek Gupta, Sridhar Sivasubbu, Vinod Scaria, Sivaprakash Ramalingam
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
β-hemoglobinopathies such as β-thalassemia (BT) and Sickle cell disease (SCD) are inherited monogenic blood disorders with significant global burden. Hence, early and affordable diagnosis can alleviate morbidity and reduce mortality given the lack
Externí odkaz:
https://doaj.org/article/a6cb5d12882b4757acc144143da96ca8
Autor:
Rajneesh Prajapat, Suman Jain
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 8, Iss 4, Pp 175-188 (2022)
Background & Aims: There is inadequate information available about the genomics and proteomics characterization of SARS-CoV-2 isolates reported from India and other part of the globe. This characterization is important for the in-silico drug designin
Externí odkaz:
https://doaj.org/article/90139862d2e84a728b7971974c1de794
Autor:
Rajneesh Prajapat, Suman Jain
Publikováno v:
Medical Laboratory Journal, Vol 16, Iss 6, Pp 26-34 (2022)
Background and objectives: The outbreak of coronavirus disease 2019 (COVID-19) has become a global health emergency. The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) NSP13 helicase plays an important role in SARS-CoV-2 replication
Externí odkaz:
https://doaj.org/article/8ed0fa7ee87648ccaa193176e547cb6d
Autor:
Abhinav Jain, Rahul C. Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Mercy Rophina, Bani Jolly, Arushi Batra, Sumit Sharma, Sanjay Siwach, Arun G. Jadhao, Nikhil V. Palande, Ganga Nath Jha, Nishat Ashrafi, Prashant Kumar Mishra, Vidhya A.K., Suman Jain, Debasis Dash, Nachimuthu Senthil Kumar, Andrew Vanlallawma, Ranjan Jyoti Sarma, Lalchhandama Chhakchhuak, Shantaraman Kalyanaraman, Radha Mahadevan, Sunitha Kandasamy, Pabitha B. M,, Raskin Erusan Rajagopal, Ezhil Ramya J., Nirmala Devi P., Anjali Bajaj, Vishu Gupta, Samatha Mathew, Sangam Goswami, Mohit Mangla, Savinitha Prakash, Kandarp Joshi, Meyakumla, Sreedevi S., Devarshi Gajjar, Ronibala Soraisham, Rohit Yadav, Yumnam Silla Devi, Aayush Gupta, Mitali Mukerji, Sivaprakash Ramalingam, Binukumar B. K., Vinod Scaria, Sridhar Sivasubbu
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Autoinflammatory disorders are the group of inherited inflammatory disorders caused due to the genetic defect in the genes that regulates innate immune systems. These have been clinically characterized based on the duration and oc
Externí odkaz:
https://doaj.org/article/d37b2fc25f074d15ac6770cc2899063c
Autor:
Rohit Singh Rawat, Aksheev Bhambri, Muneesh Pal, Avishek Roy, Suman Jain, Beena Pillai, Arpita Konar
Publikováno v:
eLife, Vol 11 (2022)
Escalated and inappropriate levels of aggressive behavior referred to as pathological in psychiatry can lead to violent outcomes with detrimental impact on health and society. Early life stressful experiences might increase the risk of developing pat
Externí odkaz:
https://doaj.org/article/9b9e8925fa7b497ab5fa0152fb95e79e
Publikováno v:
Journal of Magnetic Resonance Open, Vol 10, Iss , Pp 100050- (2022)
Parkinson's Disease (PD) is a heterogenous, neurodegenerative disease with distinct pathophysiological progression. Symptom specific biomarkers may help in early diagnosis, differentiating PD subgroups and in identifying early changes associated with
Externí odkaz:
https://doaj.org/article/64a81cff894d4f3da8fd183143626d77
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 6, Iss 1, Pp 1-17 (2020)
Abstract Background The current investigation is focused on the development and characterization of Eudragit S100 coated nitazoxanide-loaded microbeads as colon-targeted system utilizing central composite design (CCD) and desirability function. The s
Externí odkaz:
https://doaj.org/article/99422275adf84a3ea401b5cdb6f062c0
Publikováno v:
Journal of Krishna Institute of Medical Sciences University, Vol 09, Iss 03, Pp 40-47 (2020)
Background: Hyperemesis Gravidarum (HG) is a common pregnancy complication that occurs in 0.3–2% of pregnancies. Growth/Differentiation Factor (GDF) 15 serum levels are abnormally high in patients associated with HG. In silico analysis provides
Externí odkaz:
https://doaj.org/article/b4cb06e8e43b4082b0d97e23978e7810