Zobrazeno 1 - 10
of 5 844
pro vyhledávání: '"SUBSTRATE-BINDING"'
Autor:
Vibhu Jha, Leif A. Eriksson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract The mitochondrial enzyme methylenetetrahydrofolate dehydrogenase (MTHFD2) is involved in purine and thymidine synthesis via 1C metabolism. MTHFD2 is exclusively overexpressed in cancer cells but absent in most healthy adult human tissues. Ho
Externí odkaz:
https://doaj.org/article/c7b319449a7e40df8795f0d51351fc2e
Autor:
Ki Hyun Nam
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 110905- (2024)
The monomeric red fluorescent protein DsRed (mDsRed) is an optical probe widely used in multicolor applications in flow cytometry and fluorescence microscopy. Although the crystal structure of monomeric DsRed has been determined, its molecular dynami
Externí odkaz:
https://doaj.org/article/72668ff2030742fd9ab8edc02aea21bc
Publikováno v:
Advanced Agrochem, Vol 3, Iss 2, Pp 126-132 (2024)
Poly (butylene adipate-co-terephthalate), PBAT, is one of the most popular plastics nowadays and is becoming a large burden to the environment when PBAT waste is accumulated. Biodegradation of PBAT is an environmentally friendly method to treat PBAT
Externí odkaz:
https://doaj.org/article/e2a53a8013764521aa05d360f610e636
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
The pathogenic nature of bacteria can be increased by cleaving antimicrobial peptides using omptins, to avoid or counter the host’s natural immune defenses. Plasmid-encoded OmpT (pOmpT or ArlC) in avian pathogenic Escherichia coli (APEC), like the
Externí odkaz:
https://doaj.org/article/f37326ae490046bb9af6c0b24ee4bdcd
Autor:
Andrei Izvolski, Aleksei Kuznetsov
Publikováno v:
Proceedings of the Estonian Academy of Sciences, Vol 72, Iss 4, Pp 393-401 (2023)
Allosteric regulation by ATP of peptide binding with a cAMP-dependent protein kinase catalytic subunit was comÂputationally modeled by combining conventional docking analysis and molecular dynamics calculations. It was found that the peptide docki
Externí odkaz:
https://doaj.org/article/075e8ac017164d5093f9d853aee30a7b
Autor:
Nana Sakata, Shigeru Shimamoto, Yuri Murakami, Orika Ashida, Toshiki Takei, Mitsuhiro Miyazawa, Yuji Hidaka
Publikováno v:
Molecules, Vol 29, Iss 22, p 5476 (2024)
To investigate the substrate recognition mechanism of trypsin-like protease cocoonase (CCN), mutational analyses were conducted at key substrate recognition sites, Asp187 and Ser188, and their effects on substrate specificity and enzymatic activity w
Externí odkaz:
https://doaj.org/article/9728db39e7354480bf6a18ae9ed602b3
Autor:
Holly Towell, Doreen Braun, Alexander Brol, Andrea di Fonzo, Eddy Rijntjes, Josef Köhrle, Ulrich Schweizer, Clemens Steegborn
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1373 (2024)
Iodothyronine deiodinases (Dio) are selenocysteine-containing membrane enzymes that activate and inactivate the thyroid hormones (TH) through reductive iodide eliminations. The three deiodinase isoforms are homodimers sharing highly conserved amino a
Externí odkaz:
https://doaj.org/article/907f963ea57340ad810a8e44403b42ad
Autor:
Ki Hyun Nam
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110114- (2024)
Radiation damage is an inherent issue in X-ray crystallography. It not only damages macromolecular crystals, which lowers the quality of the diffraction intensity, but results in inaccurate structural information. Among the various types of radiation
Externí odkaz:
https://doaj.org/article/1ef621baa007470598cd1270fb8508e8
Akademický článek
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Publikováno v:
Molecules, Vol 29, Iss 18, p 4414 (2024)
Oxalate decarboxylase is an Mn- and O2-dependent enzyme in the bicupin superfamily that catalyzes the redox-neutral disproportionation of the oxalate monoanion to form carbon dioxide and formate. Its best-studied isozyme is from Bacillus subtilis whe
Externí odkaz:
https://doaj.org/article/0785a9b4a59f409c94d15d5def33cbfa