Zobrazeno 1 - 10
of 84
pro vyhledávání: '"STUART WALBRIDGE"'
Autor:
Ashish H. Shah, Sarah R. Rivas, Tara T. Doucet-O’Hare, Vaidya Govindarajan, Catherine DeMarino, Tongguang Wang, Leonel Ampie, Yong Zhang, Yeshavanth Kumar Banasavadi-Siddegowda, Stuart Walbridge, Dragan Maric, Marta Garcia-Montojo, Robert K. Suter, Myoung-Hwa Lee, Kareem A. Zaghloul, Joseph Steiner, Abdel G. Elkahloun, Jay Chandar, Deepa Seetharam, Jelisah Desgraves, Wenxue Li, Kory Johnson, Michael E. Ivan, Ricardo J. Komotar, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8% of the human genome. Although normally silenced, the most recently integrated provirus HERV-K (HML-2) can be reactivated in certain cancers. Here, we report pa
Externí odkaz:
https://doaj.org/article/b841f1b345c0461faf2a96f0d318229b
Autor:
Aimee L. Dowling, Stuart Walbridge, Celine Ertekin, Sriya Namagiri, Krystal Camacho, Ashis Chowdhury, Jean-Paul Bryant, Eric Kohut, John D. Heiss, Desmond A. Brown, Sangamesh G. Kumbar, Yeshavanth Kumar Banasavadi-Siddegowda
Publikováno v:
Cells, Vol 12, Iss 21, p 2562 (2023)
Glioblastoma is the most common malignant primary brain tumor. The outcome is dismal, despite the multimodal therapeutic approach that includes surgical resection, followed by radiation and chemotherapy. The quest for novel therapeutic targets to tre
Externí odkaz:
https://doaj.org/article/a2a25bc8c4914f2f9d2697c28c7973a6
Autor:
Victoria E. Sanchez, John P. Lynes, Stuart Walbridge, Xiang Wang, Nancy A. Edwards, Anthony K. Nwankwo, Hannah P. Sur, Gifty A. Dominah, Arnold Obungu, Nicholas Adamstein, Pradeep K. Dagur, Dragan Maric, Jeeva Munasinghe, John D. Heiss, Edjah K. Nduom
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/961c8f038e0d41cb909920077027cef5
Autor:
MARTIN W. BRECHBIEL, MARY CLONINGER, STUART WALBRIDGE, DIANE MILENIC, ADRIANA L. LODDER, ERIC WOLLER, NIKOLAY MOLLOV, ALEXANDER T. YORDANOV
Publikováno v:
Journal of the Serbian Chemical Society, Vol 70, Iss 2, Pp 163-170 (2005)
Prolonging the circulation of an imaging agent is vital for making it suitable for blood pool (vascular) imaging. Medical applications of vascular imaging include cardiovascular disease, abnormal capillary permeability, and tumor neovascularity. As l
Externí odkaz:
https://doaj.org/article/ddac67d684864654801c049fcce33253
Autor:
Andreas Androutsellis-Theotokis, Stuart Walbridge, Deric M Park, Russell R Lonser, Ronald D G McKay
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10841 (2010)
New mechanisms that regulate neural stem cell (NSC) expansion will contribute to improved assay systems and the emerging regenerative approach that targets endogenous stem cells. Expanding knowledge on the control of stem cell self renewal will also
Externí odkaz:
https://doaj.org/article/3e347f6deaa748b0b3e46f8b6ba727a0
Autor:
Andreas Androutsellis-Theotokis, Maria A Rueger, Deric M Park, Justin D Boyd, Raji Padmanabhan, Loraine Campanati, Craig V Stewart, Yann LeFranc, Dietmar Plenz, Stuart Walbridge, Russell R Lonser, Ronald D G McKay
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9414 (2010)
The ability to grow a uniform cell type from the adult central nervous system (CNS) is valuable for developing cell therapies and new strategies for drug discovery. The adult mammalian brain is a source of neural stem cells (NSC) found in both neurog
Externí odkaz:
https://doaj.org/article/0d236fde47db43fc807832f757dcfba8
Autor:
Armin Mortazavi, Islam Fayed, Muzna Bachani, Tyrone Dowdy, Jahandar Jahanipour, Anas Khan, Jemima Owotade, Stuart Walbridge, Sara K Inati, Joseph Steiner, Jing Wu, Mark Gilbert, Chun Zhang Yang, Mioara Larion, Dragan Maric, Alexander Ksendzovsky, Kareem A Zaghloul
Publikováno v:
Neuro Oncol
Background Uncontrolled seizures in patients with gliomas have a significant impact on quality of life and morbidity, yet the mechanisms through which these tumors cause seizures remain unknown. Here, we hypothesize that the active metabolite d-2-hyd
Autor:
Alexander Ksendzovsky, Muznabanu Bachani, Marcelle Altshuler, Stuart Walbridge, Armin Mortazavi, Mitchell Moyer, Chixiang Chen, Islam Fayed, Joseph Steiner, Nancy Edwards, Sara K Inati, Jahandar Jahanipour, Dragan Maric, John D Heiss, Jaideep Kapur, Kareem A Zaghloul
Publikováno v:
Brain Commun
Recent studies suggest that changes in neuronal metabolism are associated with epilepsy. High rates of ATP depletion, lactate dehydrogenase A and lactate production have all been found in epilepsy patients, animal and tissue culture models. As such,
Autor:
Ashish Harish Shah, Sarah Rivas, Tara Doucet-Ohare, Vaidya Govindarajan, Catherine DeMarino, Leonel Ampie, Yeshavanath Banasavadi-Siddegowda, Dragan Maric, Rob Suter, Myoung-hwa Lee, Kareem A. Zaghloul, Stuart Walbridge, Marta Garcia-Montojo, Joe Steiner, Kory Johnson, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
Neurosurgery. 69:66-67
Adenosine A2A Receptor Activation Enhances Blood–Tumor Barrier Permeability in a Rodent Glioma Model
Autor:
Jessica Bills, Meili Zhang, Dionne Davis, Monica Manglani, Kunio Nagashima, Stuart Walbridge, Brandon Foster, Dorian B. McGavern, Priya Shankarappa, Amélie Vézina, DreeAnna Morris, Matthew McCord, Hua Song, Jessica Kindrick, William D. Figg, Wei Zhang, Leslie L. Muldoon, Sadhana Jackson, Mark R. Gilbert, Cody J. Peer
Publikováno v:
Mol Cancer Res
The blood–tumor barrier (BTB) limits the entry of effective chemotherapeutic agents into the brain for treatment of malignant tumors like glioblastoma. Poor drug entry across the BTB allows infiltrative glioma stem cells to evade therapy and develo