The Axial Alignment of Titin on the Muscle Thick Filament Supports Its Role as a Molecular Ruler

Autor: Mathias Gautel, Pauline M. Bennett, Martin Rees

Publikováno v: Journal of Molecular Biology

The giant protein titin is expressed in vertebrate striated muscle where it spans half a sarcomere from the Z-disc to the M-band and is essential for muscle organisation, activity and health. The C-terminal portion of titin is closely associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e7d6b85a9760ba2a06599ea0dd32de
http://europepmc.org/articles/PMC7427331

Membrane therapy using DHA suppresses epidermal growth factor receptor signaling by disrupting nanocluster formation

Autor: Gabriella Webster, Jason Karpac, Michael L. Salinas, Ian R. Corbin, Sergio Cortes-Acosta, Robert S. Chapkin, Mohamed Mlih, Xiaoli Wang, Natividad R. Fuentes

Publikováno v: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100026-(2021)

Epidermal growth factor receptor (EGFR) signaling drives the formation of many types of cancer, including colon cancer. Docosahexaenoic acid (DHA, 22∶6Δ4,7,10,13,16,19), a chemoprotective long-chain n-3 polyunsaturated fatty acid suppresses EGFR s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c87618c51617f9f8aea6c148fae7ca3
https://doi.org/10.1016/j.jlr.2021.100026

Caracterització de l'orientació molecular en super-resolució

Autor: Zhao, Yibing

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

Treball final de màster oficial fet en col·laboració amb Universitat Autònoma de Barcelona (UAB), Universitat de Barcelona (UB) i Institut de Ciències Fotòniques (ICFO) In this thesis we aim to characterize the effect of molecular dipole orient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e7567fa9685c875261b2e191e2db199
https://hdl.handle.net/2099.1/19409

A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in Vero E6 cells.

Autor: Storti B; NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, Piazza San Silvestro 12, 56127 Pisa, Italy., Quaranta P; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy., Di Primio C; Istituto di Neuroscienze - CNR, Via Moruzzi 1, 56124 Pisa, Italy., Clementi N; Laboratory of Medical Microbiology and Virology, University 'Vita-Salute' San Raffaele, Via Olgettina, 58, 20132 Milan, Italy.; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy., Mancini N; Laboratory of Medical Microbiology and Virology, University 'Vita-Salute' San Raffaele, Via Olgettina, 58, 20132 Milan, Italy.; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy., Criscuolo E; Laboratory of Medical Microbiology and Virology, University 'Vita-Salute' San Raffaele, Via Olgettina, 58, 20132 Milan, Italy.; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy., Spezia PG; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy., Carnicelli V; Department of Surgical, Medical and Molecular Pathology, and Critical Care Medicine, University of Pisa, Via Roma 65, 5616 Pisa, Italy., Lottini G; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy., Paolini E; Department of Mathematics, University of Pisa, Largo Bruno Pontecorvo 5, 56127 Pisa, Italy., Freer G; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy., Lai M; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy., Costa M; Istituto di Neuroscienze - CNR, Via Moruzzi 1, 56124 Pisa, Italy., Beltram F; NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, Piazza San Silvestro 12, 56127 Pisa, Italy., Diaspro A; DIFILAB, Dipartimento di Fisica, Università degli Studi di Genova, Via Dodecaneso 33, 16146 Genova, Italy.; Nanoscopy, CHT, Istituto Italiano di Tecnologia, Via E. Melen 83, 16152 Genoa, Italy., Pistello M; Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, SS 12 Dell'Abetone e del Brennero 2, 56127 Pisa, Italy.; Pisa University Hospital, Via Pietro Trivella, 56126, Pisa, Italy., Zucchi R; Department of Surgical, Medical and Molecular Pathology, and Critical Care Medicine, University of Pisa, Via Roma 65, 5616 Pisa, Italy., Bianchini P; Nanoscopy, CHT, Istituto Italiano di Tecnologia, Via E. Melen 83, 16152 Genoa, Italy., Signore G; Fondazione Pisana per la Scienza, via F. Giovannini 13, 56017 San Giuliano Terme, PI, Italy., Bizzarri R; NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, Piazza San Silvestro 12, 56127 Pisa, Italy.; Department of Surgical, Medical and Molecular Pathology, and Critical Care Medicine, University of Pisa, Via Roma 65, 5616 Pisa, Italy.; Nanoscopy, CHT, Istituto Italiano di Tecnologia, Via E. Melen 83, 16152 Genoa, Italy.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2021; Vol. 19, pp. 6140-6156. Date of Electronic Publication: 2021 Nov 02.

Microscopy tools for the investigation of intracellular lipid storage and dynamics.

Autor: Daemen S; Department of Human Movement Sciences and Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands. Electronic address: sabine.daemen@maastrichtuniversity.nl., van Zandvoort MAMJ; Department of Genetics and Molecular Cell Biology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany. Electronic address: mamj.vanzandvoort@maastrichtuniversity.nl., Parekh SH; Department of Molecular Spectroscopy, Max Planck Institute for Polymer Research, Mainz, Germany. Electronic address: parekh@mpip-mainz.mpg.de., Hesselink MKC; Department of Human Movement Sciences and Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands. Electronic address: matthijs.hesselink@maastrichtuniversity.nl.

Publikováno v: Molecular metabolism [Mol Metab] 2015 Dec 31; Vol. 5 (3), pp. 153-163. Date of Electronic Publication: 2015 Dec 31 (Print Publication: 2016).