Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects Systematic Review and Meta-regression Analysis

Autor: Bassler, D, Briel, M, Montori, VM, Lane, M, Glasziou, P, Zhou, Q, Heels-Ansdell, D, Walter, SD, Guyatt, GH, Urrutia G., STOPIT-2 Study Grp

Publikováno v: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Universitat Politècnica de Catalunya (UPC)

Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping. Objective To compare the treatme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::3e4ca80447daf5a505398966ddc89da3
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