How Fragile We Are: Influence of Stimulator of Interferon Genes (STING) Variants on Pathogen Recognition and Immune Response Efficiency

Autor: Giampaolo Barone, Antonio Monari, Tao Jiang, Cécilia Hognon, Elise Dumont, Emmanuelle Bignon, Jeremy Morere, Tom Miclot

Publikováno v: Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, 2022, 62 (12), pp.3096-3106. ⟨10.1021/acs.jcim.2c00315⟩

The STimulator of INterferon Genes (STING) protein is a cornerstone of the human immune response. Its activation by cGAMP upon the presence of cytosolic DNA stimulates the production of type I interferons and inflammatory cytokines which are crucial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853a524e103e7158027851467c6ff409
https://pubmed.ncbi.nlm.nih.gov/35675714

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