Zobrazeno 1 - 6
of 6
pro vyhledávání: '"STING, stimulator of IFN genes"'
Publikováno v:
The Journal of Biological Chemistry
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm. In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell, with a molecular mass of ∼110 MDa and consisting of 8 to 64 copies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9f9983e508bac0c97b5ff5b06fddd2
https://doi.org/10.1016/j.jbc.2021.100856
https://doi.org/10.1016/j.jbc.2021.100856
Publikováno v:
Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild, self-limited constitutional symptoms to a hyperinflammatory state (“cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e4689841f74ac38cec0654832a5ece
https://doi.org/10.1016/j.jaci.2020.07.001
https://doi.org/10.1016/j.jaci.2020.07.001
Autor:
Joseph M Dybas, Chris Boutell, Joseph Hughes, Matthew D. Weitzman, Milagros Collados Rodriguez
Publikováno v:
Virus Research
Highlights • ICP0 is a viral E3 ubiquitin ligase that promotes HSV-1 infection. • ICP0 interacts with multiple component proteins of the ubiquitin pathway. • ICP0 disrupts multiple cellular processes activated in response to infection • ICP0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fee1e83e77561ad7b9c20abb9897ff
https://doi.org/10.1016/j.virusres.2020.198015
https://doi.org/10.1016/j.virusres.2020.198015
Autor:
Eliana M. Coccia, Angela Battistini
Publikováno v:
Seminars in Immunology
Highlights • Type I interferon represents the first line of innate host defense against a number of invading pathogens that also instructs adaptive immunity. • Type I interferon induction downstream germ-line-encoded pattern recognition receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088198a3fa76b174a841b353322ff121
https://doi.org/10.1016/j.smim.2015.03.005
https://doi.org/10.1016/j.smim.2015.03.005
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, 429(22), 3441-3470
Journal of Molecular Biology, 429(22), 3441-3470
Post-translational modification of cellular proteins by ubiquitin regulates numerous cellular processes, including innate and adaptive immune responses. Ubiquitin-mediated control over these processes can be reversed by cellular deubiquitinating enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514c992f4af62b6377de3148f43a3b91
https://pubmed.ncbi.nlm.nih.gov/28625850
https://pubmed.ncbi.nlm.nih.gov/28625850
Autor:
Martina Schröder, Anthony Fullam
Publikováno v:
Biochimica et Biophysica Acta. Gene Regulatory Mechanisms
Traditional functions of DExD/H-box helicases are concerned with RNA metabolism; they have been shown to play a part in nearly every cellular process that involves RNA. On the other hand, it is accepted that DexD/H-box helicases also engage in activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06865ebe4b87670387dc5d4645d0f6e
http://eprints.maynoothuniversity.ie/5013/
http://eprints.maynoothuniversity.ie/5013/
