Zobrazeno 1 - 10
of 31
pro vyhledávání: '"STEPHEN RENNARD"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Cigarette smoking is an important risk factor for cardiac diseases. In the current study, we sought to assess the effect of electronic cigarette extract (ECE) and conventional cigarette smoke extract (CSE) on cardiomyocytes. Metho
Externí odkaz:
https://doaj.org/article/1f3f30c513c8445a8a7296ec810df4e8
Autor:
Agnieszka Król, Robert Palmér, Virginie Rondeau, Stephen Rennard, Ulf G. Eriksson, Alexandra Jauhiainen
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Chronic obstructive pulmonary disease (COPD) clinical trials aimed at evaluating treatment effects on exacerbations often suffer from early discontinuations of randomized treatment. Treatment discontinuations imply a loss of infor
Externí odkaz:
https://doaj.org/article/d1eb06c5383c4c59a2507108f703fde3
Autor:
Ma’en Obeidat, Yunlong Nie, Virginia Chen, Casey P. Shannon, Anand Kumar Andiappan, Bernett Lee, Olaf Rotzschke, Peter J. Castaldi, Craig P. Hersh, Nick Fishbane, Raymond T. Ng, Bruce McManus, Bruce E. Miller, Stephen Rennard, Peter D. Paré, Don D. Sin
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Chronic obstructive pulmonary disease (COPD) is currently the third leading cause of death and there is a huge unmet clinical need to identify disease biomarkers in peripheral blood. Compared to gene level differential expression
Externí odkaz:
https://doaj.org/article/14821bba095a4017aeacc69c0fa6fb4d
Autor:
Hesham Basma, Adelaide N. Johanson, Kajari Dhar, Daniel Anderson, Fang Qiu, Stephen Rennard, Brian D. Lowes
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02633- (2019)
Purpose: The mechanisms for persistent and progressive loss of myocardial function in advanced heart failure (HF) remain incompletely characterized. In the current study, we sought to determine the impact of TGF-β on fibroblasts transcriptional prof
Externí odkaz:
https://doaj.org/article/45a505f25b1740888d624473d6b2b998
Autor:
Helen K. Reddel, Maria Gerhardsson de Verdier, Alvar Agustí, Gary Anderson, Richard Beasley, Elisabeth H. Bel, Christer Janson, Barry Make, Richard J. Martin, Ian Pavord, David Price, Christina Keen, Asparuh Gardev, Stephen Rennard, Alecka Sveréus, Aruna T. Bansal, Lance Brannman, Niklas Karlsson, Javier Nuevo, Fredrik Nyberg, Simon S. Young, Jørgen Vestbo
Publikováno v:
ERJ Open Research, Vol 5, Iss 1 (2019)
Asthma and chronic obstructive pulmonary disease (COPD) have overlapping clinical features and share pathobiological mechanisms but are often considered distinct disorders. Prospective, observational studies across asthma, COPD and asthma–COPD over
Externí odkaz:
https://doaj.org/article/94344c7fc4684db09a24b7b6c4cf5c7a
Autor:
Eitan Halper-Stromberg, Lucas Gillenwater, Charmion Cruickshank-Quinn, Wanda Kay O’Neal, Nichole Reisdorph, Irina Petrache, Yonghua Zhuang, Wassim W. Labaki, Jeffrey L. Curtis, James Wells, Stephen Rennard, Katherine A. Pratte, Prescott Woodruff, Kathleen A. Stringer, Katerina Kechris, Russell P. Bowler
Publikováno v:
Metabolites, Vol 9, Iss 8, p 157 (2019)
Smoking causes chronic obstructive pulmonary disease (COPD). Though recent studies identified a COPD metabolomic signature in blood, no large studies examine the metabolome in bronchoalveolar lavage (BAL) fluid, a more direct representation of lung c
Externí odkaz:
https://doaj.org/article/2fa63378fe234c08b6d908e0ee8b9c3c
Autor:
Ma'en Obeidat, Nick Fishbane, Yunlong Nie, Virginia Chen, Zsuzsanna Hollander, Scott J Tebbutt, Yohan Bossé, Raymond T Ng, Bruce E Miller, Bruce McManus, Stephen Rennard, Peter D Paré, Don D Sin
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140022 (2015)
BACKGROUND:COPD is currently the fourth leading cause of death worldwide. Statins are lipid lowering agents with documented cardiovascular benefits. Observational studies have shown that statins may have a beneficial role in COPD. The impact of stati
Externí odkaz:
https://doaj.org/article/f5b3a715e81f49a5b3de9c708de72ad8
Autor:
Weiliang Qiu, Michael H Cho, John H Riley, Wayne H Anderson, Dave Singh, Per Bakke, Amund Gulsvik, Augusto A Litonjua, David A Lomas, James D Crapo, Terri H Beaty, Bartolome R Celli, Stephen Rennard, Ruth Tal-Singer, Steven M Fox, Edwin K Silverman, Craig P Hersh, ECLIPSE Investigators
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24395 (2011)
Previous expression quantitative trait loci (eQTL) studies have performed genetic association studies for gene expression, but most of these studies examined lymphoblastoid cell lines from non-diseased individuals. We examined the genetics of gene ex
Externí odkaz:
https://doaj.org/article/dd2c23302603410a9bf31fb56ad7a7ae
Autor:
Richard Casaburi, Debora Merrill, Thomas M. Dolmage, Judith Garcia-Aymerich, Malin Fageras, Roger Goldstein, Gale Harding, Nancy Kline Leidy, François Maltais, Denis O’Donnell, Janos Porszasz, Luis Puente-Maestu, Stephen Rennard, Frank Sciurba, Martijn A. Spruit, Ruth Tal-Singer, Kay Tetzlaff, Alex van ’t Hul, Ren Yu, Alan Hamilton
Publikováno v:
Chronic Obstr Pulm Dis
Chronic obstructive pulmonary diseases (Miami, Fla.), vol 9, iss 4
Chronic Obstructive Pulmonary Diseases. Journal of the Copd Foundation, 9, 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9, 4, pp. 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9(4), 520-537. COPD Foundation
Chronic obstructive pulmonary diseases (Miami, Fla.), vol 9, iss 4
Chronic Obstructive Pulmonary Diseases. Journal of the Copd Foundation, 9, 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9, 4, pp. 520-537
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 9(4), 520-537. COPD Foundation
INTRODUCTION: The COPD Biomarkers Qualification Consortium (CBQC) was formed under COPD Foundation management, with the goal of qualifying biomarkers and clinical outcome assessments through established regulatory processes for chronic obstructive pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cac6ec7758c34e5bfbbc4ea550d636d
https://pubmed.ncbi.nlm.nih.gov/36066494
https://pubmed.ncbi.nlm.nih.gov/36066494
Autor:
YISHA LI, REBECCA B. CONWAY, KENDRA YOUNG, KATHERINE A. PRATTE, DINAH FOER, STEPHEN RENNARD, ERIN AUSTIN, YEONGJIN GWON, GREGORY L. KINNEY
Publikováno v:
Diabetes. 71
Rationale: Type 2 Diabetes (T2D) is one of the leading chronic diseases among smokers. Chronic obstructive pulmonary disease (COPD) is common among people with diabetes, with the lung posited as an additional target organ of diabetes. Previous litera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb09d939c519ecbfa71e90be8f4c6102
https://doi.org/10.2337/db22-1238-p
https://doi.org/10.2337/db22-1238-p