Zobrazeno 1 - 10
of 272
pro vyhledávání: '"STEPHEN R. BAKER"'
Autor:
Stephen R. Baker, Georgia Halliday, Michal Ząbczyk, Ghadir Alkarithi, Fraser L. Macrae, Anetta Undas, Beverley J. Hunt, Robert A. S. Ariëns
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-5 (2023)
Baker et al. report the presence of aggregates, possibly composed of amyloid fibrin or other plasma proteins, in blood plasma from patients with acute pulmonary embolism. These aggregates are reduced after treatment with low molecular weight heparin
Externí odkaz:
https://doaj.org/article/b62c5f58162a4860aecfbbbce0048504
Autor:
Ali Daraei, Marlien Pieters, Stephen R. Baker, Zelda de Lange-Loots, Aleksander Siniarski, Rustem I. Litvinov, Caroline S. B. Veen, Moniek P. M. de Maat, John W. Weisel, Robert A. S. Ariëns, Martin Guthold
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1536 (2021)
Scanning Electron Microscopy (SEM) is a powerful, high-resolution imaging technique widely used to analyze the structure of fibrin networks. Currently, structural features, such as fiber diameter, length, density, and porosity, are mostly analyzed ma
Externí odkaz:
https://doaj.org/article/dd8dd48477f94d0a8ce5e81e78213674
Autor:
Helen R McPherson, Cedric Duval, Stephen R Baker, Matthew S Hindle, Lih T Cheah, Nathan L Asquith, Marco M Domingues, Victoria C Ridger, Simon DA Connell, Khalid M Naseem, Helen Philippou, Ramzi A Ajjan, Robert AS Ariëns
Publikováno v:
eLife, Vol 10 (2021)
Fibrinogen is essential for blood coagulation. The C-terminus of the fibrinogen α-chain (αC-region) is composed of an αC-domain and αC-connector. Two recombinant fibrinogen variants (α390 and α220) were produced to investigate the role of subre
Externí odkaz:
https://doaj.org/article/c1db5394e1864b85a4927dd251608dff
Autor:
Keith Bonin, Sudhakar Prasad, Will Caulkins, George Holzwarth, Stephen R. Baker, Pierre-Alexandre Vidi
Publikováno v:
Journal of Biomedical Optics. 27
Three-dimensional (3D) imaging and object tracking is critical for medical and biological research and can be achieved by multifocal imaging with diffractive optical elements (DOEs) converting depth (To precisely track microscopic fluorescent objects
Autor:
Keith Bonin, Sudhakar Prasad, Will Caulkins, George Holzwarth, Stephen R. Baker, Pierre-Alexandre Vidi
Publikováno v:
Biophysical Journal. 122:130a-131a
Autor:
Stephen R. Baker, Robert A. S. Ariëns, Grzegorz Gajos, Krzysztof Piotr Malinowski, Jadwiga Nessler, Cédric Duval, Aleksander Siniarski
Publikováno v:
Thrombosis Research. 205:110-119
Introduction\ud \ud Coronary artery disease is associated with impaired clot structure. The aim of this study was to investigate acute phase myocardial infarction (AMI) and provide detailed quantitative analysis of clot ultrastructure.\ud \ud Materia
Autor:
Cédric Duval, Robert A. S. Ariëns, Rui-Gang Xu, Helen R. McPherson, Iain W. Manfield, Alexandre Slater, Steve P. Watson, Stephen R. Baker, Julia S. Gauer, Eleyna M. Martin, Arkadiusz Bonna
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: GPVI (glycoprotein VI) is a key molecular player in collagen-induced platelet signaling and aggregation. Recent evidence indicates that it also plays important role in platelet ag
Objective: GPVI (glycoprotein VI) is a key molecular player in collagen-induced platelet signaling and aggregation. Recent evidence indicates that it also plays important role in platelet ag
Publikováno v:
World Neurosurgery. 142:218-221
Background This report describes a technique for an immediate mechanical intervention using a familiar tool for emergency physicians and trauma surgeons to temporize acute epidural bleeding with mass effect. The Monro-Kellie Doctrine suggests that im
Autor:
Nathan L. Asquith, Cédric Duval, Artem Zhmurov, Stephen R. Baker, Helen R. McPherson, Marco M. Domingues, Simon D. A. Connell, Valeri Barsegov, Robert A. S. Ariëns
Publikováno v:
Blood advances. 6(13)
Fibrin polymerization involves thrombin-mediated exposure of knobs on one monomer that bind to holes available on another, leading to the formation of fibers. In silico evidence has suggested that the classical A:a knob-hole interaction is enhanced b
Autor:
Fraser L. Macrae, Claire E McKinley, Emma Linton, Polly Bowman, Anita Hill, Sam Quested, Stephen R. Baker, Robert A. S. Ariëns, Barnaby Peacock-Young, Darren J. Newton, Talha Munir, Peter Hillmen, Morag Griffin, Daniel Payne, Deborah Clarke
Publikováno v:
American Journal of Hematology. 95:944-952
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disorder, characterized by complement-mediated intravascular hemolysis and thrombosis. The increased incidence of PNH-driven thrombosis is still poorly understood, but unlike other thr