Zobrazeno 1 - 10
of 95
pro vyhledávání: '"STEFANIE MAURER"'
Autor:
Aaron Lawson McLean, Anna Cecilia Lawson McLean, Stefanie Maurer, Dorothea Nistor-Gallo, Ina Moritz, Meriem Tourbier
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101953- (2023)
Externí odkaz:
https://doaj.org/article/e03e4aa9049143cfbb98a0f10d1be97d
Autor:
Clemens Hinterleitner, Jasmin Strähle, Elke Malenke, Martina Hinterleitner, Melanie Henning, Marco Seehawer, Tatjana Bilich, Jonas Heitmann, Martina Lutz, Sven Mattern, Sophia Scheuermann, Marius Horger, Stefanie Maurer, Juliane Walz, Falko Fend, Rupert Handgretinger, Christian Seitz, Bettina Weigelin, Stephan Singer, Helmut Salih, Oliver Borst, Hans-Georg Kopp, Lars Zender
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The definition of biomarkers to predict therapy responses to immune-checkpoint inhibitors represent an unmet clinical need. Here the authors provide evidences that platelet-derived PD-L1 could serve as a prognostic and predictive biomarker in patient
Externí odkaz:
https://doaj.org/article/667bac11196140cc814118dc5b22f2f3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Over the past years navigated repetitive transcranial magnetic stimulation (nrTMS) had become increasingly important for the preoperative examination and mapping of eloquent brain areas. Among other applications it was demonstrated that the
Externí odkaz:
https://doaj.org/article/95e262ee327043e6b869ff783d4bcb74
Autor:
Susanne M. Rittig, Martina S. Lutz, Kim L. Clar, Yanjun Zhou, Korbinian N. Kropp, André Koch, Andreas D. Hartkopf, Martina Hinterleitner, Lars Zender, Helmut R. Salih, Stefanie Maurer, Clemens Hinterleitner
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In conventional T cells, OX40 has been identified as a major costimulating receptor augmenting survival and clonal expansion of effector and memory T cell populations. In regulatory T cells, (Treg) OX40 signaling suppresses cellular activity and diff
Externí odkaz:
https://doaj.org/article/5e3be70851314d40a577ae226ae4ff65
Autor:
Jenny M. Hoffmann, John R. Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U. Greiner, Stefanie Maurer, Ivet Elias, Vilborg Palsdottir, Fatima Bosch, Jeremie Boucher, Shahram Hedjazifar, Ulf Smith
Publikováno v:
Molecular Metabolism, Vol 32, Iss , Pp 15-26 (2020)
Objective: Bone morphogenetic protein 4 (BMP4) adeno-associated viral vectors of serotype 8 (AAV8) gene therapy targeting the liver prevents the development of obesity in initially lean mice by browning the large subcutaneous white adipose tissue (WA
Externí odkaz:
https://doaj.org/article/f9ddf0eaf4ad46ecababbbec31f4fdd4
Autor:
Melanie Märklin, Gundram Jung, Jonas S Heitmann, Helmut R Salih, Martina Svenja Lutz, Boris Klimovich, Stefanie Maurer, Latifa Zekri, Clemens Hinterleitner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
T cell-based immunotherapy, for example, with T cell-recruiting bispecific antibody (bsAb), has revolutionized oncological treatment. However, many patients do not respond to treatment, and long-term remissions are still rare. Several tumor immune ev
Externí odkaz:
https://doaj.org/article/963a9f7859974fbaae2d3a15ce5ef74b
Autor:
Moritz Schmidt, Vanessa Altdörfer, Sarah Schnitte, Alexander Rolf Fuchs, Korbinian Nepomuk Kropp, Stefanie Maurer, Martin Rudolf Müller, Helmut Rainer Salih, Susanne Malaika Rittig, Frank Grünebach, Daniela Dörfel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 653-664 (2019)
The ubiquitin-proteasome system is elementary for cellular protein degradation and gained rising attention as a new target for cancer therapy due to promising clinical trials with bortezomib, the first-in class proteasome inhibitor meanwhile approved
Externí odkaz:
https://doaj.org/article/f3df4d5ac33148928b5c1e666b75428b
Autor:
Hui Wang, Monja Willershäuser, Angelos Karlas, Dimitris Gorpas, Josefine Reber, Vasilis Ntziachristos, Stefanie Maurer, Tobias Fromme, Yongguo Li, Martin Klingenspor
Publikováno v:
Molecular Metabolism, Vol 20, Iss , Pp 14-27 (2019)
Objectives: Brown adipose tissue (BAT) dissipates nutritional energy as heat through uncoupling protein 1 (UCP1). The discovery of functional BAT in healthy adult humans has promoted the search for pharmacological interventions to recruit and activat
Externí odkaz:
https://doaj.org/article/0df01d6deaec48268d968eef91d6b988
Autor:
Clemens Hinterleitner, Yanjun Zhou, Claudia Tandler, Jonas S. Heitmann, Korbinian N. Kropp, Martina Hinterleitner, André Koch, Andreas D. Hartkopf, Lars Zender, Helmut R. Salih, Stefanie Maurer
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Although treatment options in breast cancer have been improved significantly, predictive biomarkers for disease progression and metastasis are still lacking. Recent studies indicate that several TNF Receptor Superfamily members are involved in breast
Externí odkaz:
https://doaj.org/article/f1e066b6d9144fb291563d5bed57ea7b
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells recognize and kill tumor cells via germ-line encoded receptors and polarized degranulation of cytotoxic molecules, respectively. As such, NK cells help to inhibit the development of cancers. The activating receptor NKG2D ind
Externí odkaz:
https://doaj.org/article/a69da262ecc74b768a0266949873cfc4