Zobrazeno 1 - 10
of 193
pro vyhledávání: '"STEFANIA STELLA"'
Autor:
Giuseppe Di Grazia, Chiara Conti, Sabrina Nucera, Gianmarco Motta, Federica Martorana, Stefania Stella, Michele Massimino, Mario Giuliano, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The REarranged during Transfection (RET) receptor tyrosine kinase plays a crucial role in the development of various anatomical structures during embryogenesis and it is involved in many physiological cellular processes. This protein is also associat
Externí odkaz:
https://doaj.org/article/4e1c648064c64df8bd05e19ae18ed0a4
Autor:
Manlio Fazio, Calogero Vetro, Uroš Markovic, Andrea Duminuco, Marina Parisi, Cinzia Maugeri, Elisa Mauro, Nunziatina Laura Parrinello, Fabio Stagno, Loredana Villari, Anna Maria Triolo, Stefania Stella, Giuseppe A. Palumbo, Francesco Di Raimondo, Alessandra Romano, Roberta Zanotti
Publikováno v:
Clinical Case Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Aggressive SM + AML has limited therapeutic options. Even a strong combination of decitabine–venetoclax–midostaurin has a transient effect on AML and a mitigated effect on SM. Larger series are required to identify the best therapeutic s
Externí odkaz:
https://doaj.org/article/ad426aa945fb49c6a3745848a1c8e251
Autor:
Stefania Stella, Michele Massimino, Livia Manzella, Nunziatina Laura Parrinello, Silvia Rita Vitale, Federica Martorana, Paolo Vigneri
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionBreast cancer is the most common malignancy in women, and it is linked to several risk factors including genetic alterations, obesity, estrogen signaling, insulin levels, and glucose metabolism deregulation. Insulin and Insulin-like growt
Externí odkaz:
https://doaj.org/article/dc52719f7bae45e6b29b79f0b3dd9004
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101104- (2021)
Over the last quarter century several genetic alterations have been implicated in hereditary breast cancer (HBC). Two papers recently published in the New England Journal of Medicine explored the mutation prevalence in breast cancer predisposition ge
Externí odkaz:
https://doaj.org/article/f1389bd706d04c2ea47abf5ddfd7918c
Autor:
Michele Massimino, Elena Tirrò, Stefania Stella, Livia Manzella, Maria Stella Pennisi, Chiara Romano, Silvia Rita Vitale, Adriana Puma, Cristina Tomarchio, Sandra Di Gregorio, Agostino Antolino, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic Myeloid Leukemia (CML) is a hematological disorder characterized by the clonal expansion of a hematopoietic stem cell carrying the Philadelphia chromosome that juxtaposes the BCR and ABL1 genes. The ensuing BCR-ABL1 chimeric oncogene is chara
Externí odkaz:
https://doaj.org/article/e64984d411ed458d9ee29e056ad88a5f
Autor:
Federica Martorana, Gianmarco Motta, Giuliana Pavone, Lucia Motta, Stefania Stella, Silvia Rita Vitale, Livia Manzella, Paolo Vigneri
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The serine/threonine kinase AKT is a key component of the PI3K/AKT/mTOR signaling pathway as it exerts a pivotal role in cell growth, proliferation, survival, and metabolism. Deregulation of this pathway is a common event in breast cancer including h
Externí odkaz:
https://doaj.org/article/3e62123234b6441682d4dde9eb7d7a0b
Autor:
Elena Tirrò, Michele Massimino, Chiara Romano, Federica Martorana, Maria Stella Pennisi, Stefania Stella, Giuliana Pavone, Sandra Di Gregorio, Adriana Puma, Cristina Tomarchio, Silvia Rita Vitale, Livia Manzella, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma multiforme (GBM) is the most common primary brain malignancy and is often resistant to conventional treatments due to its extensive cellular heterogeneity. Thus, the overall survival of GBM patients remains extremely poor. Insulin-like g
Externí odkaz:
https://doaj.org/article/5b3b2a650bd34cddbfe18451893beb66
Autor:
Stefania Stella, Silvia Rita Vitale, Fabio Stagno, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Francesco Di Raimondo, Emma Cacciola, Rossella Cacciola, Livia Manzella
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1051 (2022)
Background: Detection of BCR-ABL1 transcript level via real-time quantitative-polymerase-chain reaction (Q-PCR) is a clinical routine for disease monitoring, assessing Tyrosine Kinase Inhibitor therapy efficacy and predicting long-term response in ch
Externí odkaz:
https://doaj.org/article/f7d7cb5661ca4f51a9017dfe1bdc1026
Autor:
Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract The introduction of ABL Tyrosine Kinase Inhibitors (TKIs) has significantly improved the outcome of Chronic Myeloid Leukemia (CML) patients that, in large part, achieve satisfactory hematological, cytogenetic and molecular remissions. Howeve
Externí odkaz:
https://doaj.org/article/9b21a4b502ea48ec89c59850edc2e6d1
Autor:
Stefania Stella, Silvia Rita Vitale, Federica Martorana, Michele Massimino, Giuliana Pavone, Katia Lanzafame, Sebastiano Bianca, Chiara Barone, Cristina Gorgone, Marco Fichera, Livia Manzella
Publikováno v:
Cancer Management and Research. 14:1341-1352
Stefania Stella,1,2 Silvia Rita Vitale,1,2 Federica Martorana,1,2 Michele Massimino,1,2 Giuliana Pavone,3 Katia Lanzafame,3 Sebastiano Bianca,4 Chiara Barone,5 Cristina Gorgone,6 Marco Fichera,6,7 Livia Manzella1,2 1Department of Clinical and Experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f4db1258a97649a56f8a1c34d655ba
https://doi.org/10.2147/cmar.s348529
https://doi.org/10.2147/cmar.s348529