Zobrazeno 1 - 10
of 1 011
pro vyhledávání: '"STAT5B"'
Autor:
Hao Duan, Yuan Xie, Suwen Wu, Guangyin Zhao, Zhen Zeng, Hongrong Hu, Yanjiao Yu, Wanming Hu, Yuanzhong Yang, Yukun Chen, Haoqun Xie, Zexin Chen, Gao Zhang, Keith T. Flaherty, Shanshan Hu, Haineng Xu, Wenjuan Ma, Yonggao Mou
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Patients with glioblastoma (GBM) have a poor prognosis and limited treatment options. The mRNA decapping enzyme scavenger (DCPS) is a cap-hydrolyzing enzyme. The DCPS inhibitor RG3039 exhibited excellent central nervous system bio
Externí odkaz:
https://doaj.org/article/68575c1ba5124ae1b125822e21617aa9
Publikováno v:
Biologics: Targets & Therapy, Vol Volume 18, Pp 181-193 (2024)
Wen Jun Zhang,* Chong Ling Hu,* Bing Ling Guo, Xi Ping Liang, Chao Yu Wang, Tao Yang Department of Hematology Oncology, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China*These authors contributed equally to thi
Externí odkaz:
https://doaj.org/article/5ba22eaa26644c16843f3accd04c9632
Autor:
Vadim Gorodetskiy, Yulia Sidorova, Bella Biderman, Natalia Kupryshina, Natalya Ryzhikova, Andrey Sudarikov
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
BackgroundT-cell leukemia originating from large granular lymphocytes (T-LGL leukemia) is a rare lymphoid neoplasia characterized by clonal proliferation of large granular T lymphocytes expressing αβ or γδ T-cell receptor (TCR) on the cell membra
Externí odkaz:
https://doaj.org/article/fd43324f7fa4465c9a9ef0a8d7a93ad6
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-8 (2024)
Abstract Background Small intestinal monomorphic–epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare aggressive T-cell lymphoma originating in the gastrointestinal tract. This study aimed to investigate the clinicopathological features, im
Externí odkaz:
https://doaj.org/article/77bbb67ba48e4cb3aac412d895e0c02d
Publikováno v:
eLife, Vol 12 (2023)
Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is un
Externí odkaz:
https://doaj.org/article/685a18209ee34a928afdad8a23570443
Autor:
Jan Nagenborg, Han Jin, Adele V. Ruder, Lieve Temmerman, Barend Mees, Casper Schalkwijk, Daniel Müller-Klieser, Thorsten Berg, Pieter Goossens, Marjo M. P. C. Donners, Erik A. L. Biessen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInhibition of STAT5 was recently reported to reduce murine atherosclerosis. However, the role of STAT5 isoforms, and more in particular STAT5A in macrophages in the context of human atherosclerosis remains unknown.Methods and resultsHere,
Externí odkaz:
https://doaj.org/article/206556e531ef4ffba0deaedda5baeca5
Autor:
I. Garces de los Fayos Alonso, L. Zujo, I. Wiest, P. Kodajova, G. Timelthaler, S. Edtmayer, M. Zrimšek, S. Kollmann, C. Giordano, M. Kothmayer, H. A. Neubauer, S. Dey, M. Schlederer, B. S. Schmalzbauer, T. Limberger, C. Probst, O. Pusch, S. Högler, S. Tangermann, O. Merkel, A. I. Schiefer, C. Kornauth, N. Prutsch, M. Zimmerman, B. Abraham, J. Anagnostopoulos, L. Quintanilla-Martinez, S. Mathas, P. Wolf, D. Stoiber, P. B. Staber, G. Egger, W. Klapper, W. Woessmann, T. A. Look, P. Gunning, S. D. Turner, R. Moriggl, S. Lagger, L. Kenner
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Anaplastic large cell lymphoma (ALCL) is an aggressive non-Hodgkin T cell lymphoma commonly driven by NPM-ALK. AP-1 transcription factors, cJUN and JUNb, act as downstream effectors of NPM-ALK and transcriptionally regulate PDGFR
Externí odkaz:
https://doaj.org/article/539b970a07434b548704a53ef179eac3
Publikováno v:
Toxics, Vol 11, Iss 12, p 963 (2023)
Per- and poly-fluoroalkyl substances (PFAS) are a large class of fluorinated carbon chains that include legacy PFAS, such as perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorohexane sulfonate
Externí odkaz:
https://doaj.org/article/64aa44cdcf8644ee8e346d841123621f
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