Zobrazeno 1 - 10
of 310
pro vyhledávání: '"STAT3 Decoy Oligonucleotide"'
Autor:
Ramasamy, Thiruganesh1 (AUTHOR), Chen, Xucai1 (AUTHOR), Qin, Bin1 (AUTHOR), Johnson, Daniel E.2 (AUTHOR), Grandis, Jennifer R.2 (AUTHOR), Villanueva, Flordeliza S.1 (AUTHOR) villanuevafs@upmc.edu
Publikováno v:
PLoS ONE. 11/18/2020, Vol. 15 Issue 11, p1-17. 17p.
Autor:
Thiruganesh Ramasamy, Xucai Chen, Bin Qin, Daniel E Johnson, Jennifer R Grandis, Flordeliza S Villanueva
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242264 (2020)
Signal transducer and activator of transcription-3 (STAT3) is an oncogenic transcription factor implicated in carcinogenesis, tumor progression, and drug resistance in head and neck squamous cell carcinoma (HNSCC). A decoy oligonucleotide targeting S
Externí odkaz:
https://doaj.org/article/d15c6827cee1476b991da2a18aadc2fa
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2.2MB, Modified STAT3 decoys demonstrate enhanced resistance to thermal denaturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f5870414757b94ce3c02ac424e1aa7
https://doi.org/10.1158/2159-8290.22528743.v1
https://doi.org/10.1158/2159-8290.22528743.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 1.2MB, Modified STAT3 decoys bind to pSTAT3 protein with similar affinity as the parental STAT3 decoy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30539ef8faef811ec7986b2385e8d410
https://doi.org/10.1158/2159-8290.22528740.v1
https://doi.org/10.1158/2159-8290.22528740.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 107K, Systemic delivery of cyclic STAT3 decoy does not affect total or pSTAT3 expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2098d043169646d758cfedaf2f14b31a
https://doi.org/10.1158/2159-8290.22528731
https://doi.org/10.1158/2159-8290.22528731
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2.5MB, The chemistry used to generate the modified decoys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65178b04076c5c2db95c2225b4ffcfd2
https://doi.org/10.1158/2159-8290.22528746.v1
https://doi.org/10.1158/2159-8290.22528746.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 70K, Lack of anti-tumor effects of systemically administered parental STAT3 decoy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9b9985992180cd4f087112f286b66
https://doi.org/10.1158/2159-8290.22528749.v1
https://doi.org/10.1158/2159-8290.22528749.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2MB, Modified STAT3 decoys abrogate STAT3 target gene expression in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bbd05e6d8072276dd17a459c3c4745
https://doi.org/10.1158/2159-8290.22528737
https://doi.org/10.1158/2159-8290.22528737
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 165K, EC50 values of STAT3 decoy in cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f54801fbcf326d28c1e2e05e484c5d
https://doi.org/10.1158/2159-8290.22528722.v1
https://doi.org/10.1158/2159-8290.22528722.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e8e1a4b9289bc03857f29c1a70b8a4
https://doi.org/10.1158/2159-8290.22528728.v1
https://doi.org/10.1158/2159-8290.22528728.v1