Výsledky vyhledávání

Akademický článek

Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens

Autor: Rajni Upadhyay, Bhavyata Dua, Bhawna Sharma, Mohan Natrajan, Ajai Kumar Jain, Balaji Kithiganahalli Narayanaswamy, Beenu Joshi

Publikováno v: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-11 (2019)

Abstract Background Leprosy is an ideal human disease to study T cell regulation as patients show correlation between cytokine skewed Th1-Th2 responses and clinical forms of the disease. The Role of transcription factors on the modulation of Th1 and

Externí odkaz: https://doaj.org/article/8b335f5ee4bb40b5990f2f930620a0d8

Zobrazit plný text záznamu

Plný text ve formátu HTML

Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis

Autor: Sara Rufini, Cinzia Ciccacci, Paola Triggianese, Carlo Perricone, Paola Conigliaro, Roberto Perricone, Paola Borgiani, Giuseppe Novelli, Cristina Politi

Publikováno v: Clinical and Experimental Immunology. 186:157-163

Summary Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in chronic inflammation of the synovium and consequent cartilage and bone erosion. RA is associated strongly with the presence of rheumatoid factor (RF), and consists of cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28639db328e28a47829df48f53609633
https://doi.org/10.1111/cei.12831

Zobrazit plný text záznamu

Plný text ve formátu HTML

Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens

Autor: Balaji Kithiganahalli Narayanaswamy, Bhavyata Dua, Bhawna Sharma, Ajai Kumar Jain, Beenu Joshi, Mohan Natrajan, Rajni Upadhyay

Publikováno v: BMC Infectious Diseases
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-11 (2019)

Background Leprosy is an ideal human disease to study T cell regulation as patients show correlation between cytokine skewed Th1-Th2 responses and clinical forms of the disease. The Role of transcription factors on the modulation of Th1 and Th2 respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90db63f7aadf23d08e5a10572096b35e
https://pubmed.ncbi.nlm.nih.gov/30642265

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity

Autor: Houfen Su, Anshu Agrawal, Sudhir Gupta, Kathryn Osann, Sudhanshu Agrawal, Justine Chen

Publikováno v: Agrawal, Anshu; Su, Houfen; Chen, Justine; Osann, Kathryn; Agrawal, Sudhanshu; & Gupta, Sudhir. (2012). Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity.. Aging, 4(9), 648-659. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/0mk1j4qf
Aging (Albany NY)

Advancing age leads to significant decline in immune functions. IL-21 is produced primarily by T follicular helper (Tfh) cells and is required for effective immune cell functions. Here we compared the induction of IL-21 in aged and young subjects. Ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99670740025367ee68c54ec1a0b522b
http://www.escholarship.org/uc/item/0mk1j4qf

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání