Zobrazeno 1 - 10
of 697
pro vyhledávání: '"STANLEY I RAPOPORT"'
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164326 (2016)
Polyunsaturated fatty acyl (PUFA) chains in both the ω3 and ω6 series are essential for normal animal brain development, and cannot be interconverted to compensate for a dietary deficiency of one or the other. Paradoxically, a dietary ω3-PUFA defi
Externí odkaz:
https://doaj.org/article/b32a00ab7ca348199c4b9cbfe012f5e6
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132675 (2015)
Phosphoinositides, lipid-signaling molecules, participate in diverse brain processes within a wide metabolic cascade.Gene transcriptional networks coordinately regulate the phosphoinositide cascade during human brain Development and Aging.We used the
Externí odkaz:
https://doaj.org/article/009a9046770a4d68aea5aeecd2f6c77a
Publikováno v:
Biological Research, Vol 39, Iss 3, Pp 471-481 (2006)
Down syndrome is determined by the presence of an extra copy of autosome 21 and is expressed by multiple abnormalities, with mental retardation being the most striking feature. The condition results in altered electrical membrane properties of fetal
Externí odkaz:
https://doaj.org/article/8d9c7ff0193f45e9996aa37d18c8ce79
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/5d76ef0876dd4ff986bb1c9523a8353a
Autor:
Matthew Kellom, Mireille Basselin, Vasken L Keleshian, Mei Chen, Stanley I Rapoport, Jagadeesh S Rao
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/d2600ccd771a4a8f9bdfb9894a1096fa
Autor:
Veronica H Ryan, Christopher T Primiani, Jagadeesh S Rao, Kwangmi Ahn, Stanley I Rapoport, Helene Blanchard
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100858 (2014)
The polyunsaturated arachidonic and docosahexaenoic acids (AA and DHA) participate in cell membrane synthesis during neurodevelopment, neuroplasticity, and neurotransmission throughout life. Each is metabolized via coupled enzymatic reactions within
Externí odkaz:
https://doaj.org/article/13edbb7310bf47f584e52ba8189885e9
Autor:
Christopher T Primiani, Veronica H Ryan, Jagadeesh S Rao, Margaret C Cam, Kwangmi Ahn, Hiren R Modi, Stanley I Rapoport
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110972 (2014)
BACKGROUND:Age changes in expression of inflammatory, synaptic, and neurotrophic genes are not well characterized during human brain development and senescence. Knowing these changes may elucidate structural, metabolic, and functional brain processes
Externí odkaz:
https://doaj.org/article/8765b6f04a7e47c7845c4b40f654f11c
Autor:
Vasken L Keleshian, Matthew Kellom, Hyung-Wook Kim, Ameer Y Taha, Yewon Cheon, Miki Igarashi, Stanley I Rapoport, Jagadeesh S Rao
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95318 (2014)
Dietary long-chain n-3 polyunsaturated fatty acid (PUFA) supplementation may be beneficial for chronic brain illnesses, but the issue is not agreed on. We examined effects of dietary n-3 PUFA deprivation or supplementation, compared with an n-3 PUFA
Externí odkaz:
https://doaj.org/article/34756e7877e14355bc56e7240a4e894e
Autor:
John C Umhau, Weiyin Zhou, Shantalaxmi Thada, James Demar, Nahed Hussein, Abesh K Bhattacharjee, Kaizong Ma, Sharon Majchrzak-Hong, Peter Herscovitch, Norman Salem, Abigail Urish, Joseph R Hibbeln, Stephen C Cunnane, Stanley I Rapoport, Jussi Hirvonen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75333 (2013)
Chronic alcohol dependence has been associated with disturbed behavior, cerebral atrophy and a low plasma concentration of docosahexaenoic acid (DHA, 22∶6n-3), particularly if liver disease is present. In animal models, excessive alcohol consumptio
Externí odkaz:
https://doaj.org/article/349a61ee4a27497faa13b83a20432330
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Carol Miller, Patrick M. Sullivan, Hoau-Yan Wang, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/754e453573674c8fbaddf6c526d4ec90