Lung-resident CD69+ST2+ TH2 cells mediate long-term type 2 memory to inhaled antigen in mice

Autor: Kobayashi, Takao, Iijima, Koji, Matsumoto, Koji, Lama, Jyoti K., Kita, Hirohito

Publikováno v: In The Journal of Allergy and Clinical Immunology July 2023 152(1):167-181

Amphiregulin-producing TH2 cells facilitate esophageal fibrosis of eosinophilic esophagitis

Autor: Tatsuya Kaneko, MD, PhD, Chiaki Iwamura, PhD, Masahiro Kiuchi, VMD, PhD, Akane Kurosugi, MD, PhD, Miki Onoue, MD, PhD, Tomoaki Matsumura, MD, PhD, Tetsuhiro Chiba, MD, PhD, Toshinori Nakayama, MD, PhD, Naoya Kato, MD, PhD, Kiyoshi Hirahara, MD, PhD

Publikováno v: Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 3, Pp 100287- (2024)

Background: Massive eosinophil infiltration into the esophagus is associated with subepithelial fibrosis and esophageal stricture in patients with eosinophilic esophagitis (EoE). However, the pathogenesis of esophageal fibrosis remains unclear. Objec

Externí odkaz: https://doaj.org/article/bb05d57760a04e08b87307a06e9e63dc

Researchers from Mayo Clinic Detail New Studies and Findings in the Area of Genomics and Genetics (Lung-resident Cd69+st2+th2 Cells Mediate Long- Term Type 2 Memory To Inhaled Antigen In Mice).

Publikováno v: Genomics & Genetics Weekly; 9/22/2023, p1426-1426, 1p

Crystalline silica-induced recruitment and immuno-imbalance of CD4⁺ tissue resident memory T cells promote silicosis progression.

Autor: You, Yichuan^1,2 (AUTHOR), Wu, Xiulin^1,2 (AUTHOR), Yuan, Haoyang^1,2 (AUTHOR), He, Yangyang^1,2 (AUTHOR), Chen, Yinghui^1,2 (AUTHOR), Wang, Sisi^1,2 (AUTHOR), Min, Hui³ (AUTHOR), Chen, Jie^1,2 (AUTHOR) jchen@cmu.edu.cn, Li, Chao^1,2 (AUTHOR) lichao@cmu.edu.cn

Publikováno v: Communications Biology. 8/9/2024, Vol. 7 Issue 1, p1-14. 14p.

CD69 Signaling in Eosinophils Induces IL-10 Production and Apoptosis via the Erk1/2 and JNK Pathways, Respectively.

Autor: Bui, Dan Van^1,2,3 (AUTHOR) dr.linh1992@gmail.com, Nguyen, Linh Manh¹ (AUTHOR) suzukken@hirakata.kmu.ac.jp, Kanda, Akira^1,4,5 (AUTHOR) akanda@hirakata.kmu.ac.jp, Chu, Hanh Hong^1,6 (AUTHOR) iwai@hirakata.kmu.ac.jp, Thi Le, Nhi Kieu¹ (AUTHOR), Yun, Yasutaka¹ (AUTHOR), Kobayashi, Yoshiki^1,5 (AUTHOR), Suzuki, Kensuke¹ (AUTHOR), Mitani, Akitoshi¹ (AUTHOR), Shimamura, Akihiro¹ (AUTHOR), Fukui, Kenta¹ (AUTHOR), Sawada, Shunsuke⁷ (AUTHOR) sawadash@hirakata.kmu.ac.jp, Dombrowicz, David⁸ (AUTHOR) david.dombrowicz@pasteur-lille.fr, Iwai, Hiroshi¹ (AUTHOR)

Publikováno v: Biomolecules (2218-273X). Mar2024, Vol. 14 Issue 3, p360. 10p.