Zobrazeno 1 - 10
of 435
pro vyhledávání: '"SSTR2"'
Autor:
Dylan Chapeau, Savanne Beekman, Maryana Handula, Erika Murce, Corrina de Ridder, Debra Stuurman, Yann Seimbille
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-20 (2024)
Abstract Background Integrating radioactive and optical imaging techniques can facilitate the prognosis and surgical guidance for cancer patients. Using a single dual-labeled tracer ensures consistency in both imaging modalities. However, developing
Externí odkaz:
https://doaj.org/article/146801c7b094400b847694f41de23bd7
Autor:
Christian Pellegrino, Nicholas Favalli, Laura Volta, Ramon Benz, Sara Puglioli, Gabriele Bassi, Kathrin Zitzmann, Christoph Josef Auernhammer, Svenja Nölting, Chiara F. Magnani, Dario Neri, Felix Beuschlein, Markus G. Manz
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Somatostatin receptor type 2 (SSTR2) is one of the five subtypes of somatostatin receptors and is overexpressed on the surface of most gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs), pituitary tumors, paraganglioma, and meningioma, as well
Externí odkaz:
https://doaj.org/article/3ef1e2ed9ab14eb1a9a52aba835a4e4d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ionizing radiation has garnered considerable attention as a combination partner for immunotherapy due to its potential immunostimulatory effects. In contrast to the more commonly used external beam radiation, we explored the feasibility of combining
Externí odkaz:
https://doaj.org/article/1ccec8cc7cc44b3797789c2f3d40aca8
Autor:
Greta Gedvilaite-Vaicechauskiene, Loresa Kriauciuniene, Arimantas Tamasauskas, Vita Rovite, Ilona Mandrika, Sheng-Nan Wu, Chin-Wei Huang, Lina Poskiene, Rasa Liutkeviciene
Publikováno v:
Medicina, Vol 60, Iss 8, p 1252 (2024)
Background and Objectives: This study explores the complex pathogenesis of pituitary adenomas (PAs), prevalent intracranial tumors in the pituitary gland. Despite their generally benign nature, PAs exhibit a diverse clinical spectrum involving hormon
Externí odkaz:
https://doaj.org/article/94cac27050e744549fdb60a5a7012498
Autor:
Maryana Handula, Savanne Beekman, Mark Konijnenberg, Debra Stuurman, Corrina de Ridder, Frank Bruchertseifer, Alfred Morgenstern, Antonia Denkova, Erik de Blois, Yann Seimbille
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Background The [177Lu]Lu-DOTA-TATE mediated peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs) is sometimes leading to treatment resistance and disease recurrence. An interesting alternative could be the somatostati
Externí odkaz:
https://doaj.org/article/b4c3e0284752465fa8ed5d7be031a77d
Autor:
Xin Gu, Joydeb Majumder, Olena Taratula, Andriy Kuzmov, Olga Garbuzenko, Natalia Pogrebnyak, Tamara Minko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5545 (2024)
A novel nanotechnology-based drug delivery system (DDS) targeted at pancreatic cancer cells was developed, characterized, and tested. The system consisted of liposomes as carriers, an anticancer drug (paclitaxel) as a chemotherapeutic agent, and a mo
Externí odkaz:
https://doaj.org/article/2e8f5f3eb47f435d92cfe79f35388cde
Autor:
Xiao Zhang, Jiannan Zhang, Tianjiao Huang, Xinglong Wang, Jiancheng Su, Jiliang He, Ningkun Shi, Yajun Wang, Juan Li
Publikováno v:
Animals, Vol 14, Iss 7, p 1034 (2024)
Somatostatin shows an anti-lipolytic effect in both chickens and ducks. However, its molecular mediator remains to be identified. Here, we report that somatostatin type 2 receptor (SSTR2) is expressed at a high level in chicken adipose tissue. In cul
Externí odkaz:
https://doaj.org/article/aa18c575dd1a44668f35e30da1ad9bea
Publikováno v:
Journal of Mathematical and Fundamental Sciences, Vol 55, Iss 1 (2023)
Nocardiotide-A (cWIWLVA) is a cyclic peptide with significant cytotoxicity against several cancer cells. The present research aimed to design a radiopeptide based on nocardiotide-A analogues to be labeled by technetium-99m targeting SSTR2, which is t
Externí odkaz:
https://doaj.org/article/c2f11352178546548b2e9c6a9b2ca59f
Autor:
Martine Bocchini, Marcella Tazzari, Sara Ravaioli, Filippo Piccinini, Flavia Foca, Michela Tebaldi, Fabio Nicolini, Ilaria Grassi, Stefano Severi, Raffaele Adolfo Calogero, Maddalena Arigoni, Joerg Schrader, Massimiliano Mazza, Giovanni Paganelli
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) are rare diseases encompassing pancreatic (PanNETs) and ileal NETs (SINETs), characterized by heterogeneous somatostatin receptors (SSTRs) expression. Treatments for inoperable GEP-NETs are li
Externí odkaz:
https://doaj.org/article/e7851a614d4d443b97fb8a0ee8e2f70d
Autor:
Zilong Wang, Feifan Liu, Chao Li, Huisheng Yuan, Yuzhu Xiang, Chunxiao Wei, Dongyuan Zhu, Muwen Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundMetastatic pheochromocytomas and paragangliomas are rare neuroendocrine tumors with a poor prognosis. Bladder paraganglioma concomitant with urothelial papilloma is even rarer. However, the rate of tumor response to cyclophosphamide–vincr
Externí odkaz:
https://doaj.org/article/4a979b99382c42fead06b4e3be08e298