Zobrazeno 1 - 10
of 42
pro vyhledávání: '"SRILAXMI KALAVALAPALLI"'
Autor:
Fernando Bril, Srilaxmi Kalavalapalli, Romina Lomonaco, Reginald Frye, Eddison Godinez Leiva, Kenneth Cusi
Publikováno v:
JHEP Reports, Vol 6, Iss 7, Pp 101092- (2024)
Background & Aims: It has been postulated that carriers of PNPLA3 I148M (CG [Ile/Met] or GG [Met/Met]) develop metabolic dysfunction-associated steatotic liver disease (MASLD) in the absence of insulin resistance or metabolic syndrome. However, the r
Externí odkaz:
https://doaj.org/article/c27cb77df685452e953139bddaf23c08
Autor:
Kristin Alexandra Dayton, Fernando Bril, Diana Barb, Jinping Lai, Srilaxmi Kalavalapalli, Kenneth Cusi
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251449 (2021)
BackgroundHypogonadism is reported to occur in non-alcoholic fatty liver disease (NAFLD), but earlier studies used low-sensitivity diagnostic techniques (CT, ultrasound), for NAFLD diagnosis. We hypothesized that if hypogonadism was due to NAFLD, and
Externí odkaz:
https://doaj.org/article/a21b9e6913004e2a81f3a4e994607c9a
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Autor:
Joonseok Cho, Yujian Zhang, Shi-Young Park, Anna-Maria Joseph, Chul Han, Hyo-Jin Park, Srilaxmi Kalavalapalli, Sung-Kook Chun, Drake Morgan, Jae-Sung Kim, Shinichi Someya, Clayton E. Mathews, Young Jae Lee, Stephanie E. Wohlgemuth, Nishanth E. Sunny, Hui-Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S. Paul Oh, Naohiro Terada
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Adenine nucleotide translocase (ANT) 2 promotes ADP/ATP exchange across the mitochondrial inner membrane. Choet al. show that liver specific Ant2 deletion increases uncoupled respiration and protects mice against fatty liver and obesity-induced insul
Externí odkaz:
https://doaj.org/article/27c33827aff94d8b88865b49e3ea384d
Autor:
Haiping Dai, Stefan Ehrentraut, Stefan Nagel, Sonja Eberth, Claudia Pommerenke, Wilhelm G Dirks, Robert Geffers, Srilaxmi Kalavalapalli, Maren Kaufmann, Corrina Meyer, Silke Faehnrich, Suning Chen, Hans G Drexler, Roderick A F MacLeod
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0139663 (2015)
Primary mediastinal B-Cell lymphoma (PMBL) is a recently defined entity comprising ~2-10% non-Hodgkin lymphomas (NHL). Unlike most NHL subtypes, PMBL lacks recurrent gene rearrangements to serve as biomarkers or betray target genes. While druggable,
Externí odkaz:
https://doaj.org/article/d9655f5eb25a463bbfd37e81c6521f53
Publikováno v:
Diabetes, obesitymetabolismREFERENCES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144ccdbc9dd66bfc93034c60a48b25dc
https://pubmed.ncbi.nlm.nih.gov/36495442
https://pubmed.ncbi.nlm.nih.gov/36495442
Autor:
Srilaxmi Kalavalapalli, Eddison Godinez Leiva, Romina Lomonaco, Xiaofei Chi, Sulav Shrestha, Rachel Dillard, Jeffery Budd, Jessica Portillo Romero, Christina Li, Fernando Bril, George Samraj, John Pennington, Petra Townsend, Frank Orlando, Shwetha Shetty, Lydia Mansour, Lorena Rodrigues Silva-Sombra, Pierre Bedossa, John Malaty, Diana Barb, Matthew J Gurka, Kenneth Cusi
Publikováno v:
The Journal of clinical endocrinology and metabolism.
Context Although type 2 diabetes (T2D) is a risk factor for liver fibrosis in nonalcoholic fatty liver disease (NAFLD), the specific contribution of insulin resistance (IR) relative to other factors is unknown. Objective Assess the impact on liver fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc63748134627c55ac44ee90817341f9
https://pubmed.ncbi.nlm.nih.gov/36378995
https://pubmed.ncbi.nlm.nih.gov/36378995
Autor:
Meagan Gray, Charles M. Rowland, Michael J. McPhaul, Kenneth Cusi, Dov Shiffman, Romina Lomonaco, Srilaxmi Kalavalapalli, Fernando Bril, Diana Barb
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e4360-e4371
Context Patients with nonalcoholic fatty liver disease (NAFLD) are characterized by insulin resistance and hyperinsulinism. However, insulin resistance measurements have not been shown to be good diagnostic tools to predict NAFLD in prior studies. Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599c064844b5fbf7854817c9d913a6ac
https://doi.org/10.1210/clinem/dgab417
https://doi.org/10.1210/clinem/dgab417
Autor:
FERNANDO BRIL, RYAN PEARCE, TIMOTHY S. COLLIER, SRILAXMI KALAVALAPALLI, MICHAEL J. MCPHAUL, KENNETH CUSI
Publikováno v:
Diabetes. 71
Patients with T2D remain at high risk of cardiovascular (CV) events despite adequate glycemic and LDL-C control. Changes in HDL particle composition and function may explain part of this increased CV risk. The aim of this study was to determine the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4cf12469854434eb0e8149c50c1bfc0
https://doi.org/10.2337/db22-210-or
https://doi.org/10.2337/db22-210-or
Autor:
APRIL MATHEWS, SRILAXMI KALAVALAPALLI, EDDISON GODINEZ, ROMINA LOMONACO, RACHEL E. DILLARD, MARIA A. GONZALEZ, STEPHEN A. MARANGI, SHWETHA S. SHETTY, SULAV SHRESTHA, LYDIA MANSOUR, MARGERY A. CONNELLY, KELLY Y. CHUN, DIANA BARB, KENNETH CUSI
Publikováno v:
Diabetes. 71
Obesity (OB) and type 2 diabetes (T2D) are associated with NAFLD and a worse cardiometabolic profile. However, their independent contribution to steatosis, fibrosis, insulin resistance (IR) and atherogenic dyslipidemia are controversial. To this end,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc5631dd704491a74cc8541cd4b6e69
https://doi.org/10.2337/db22-1346-p
https://doi.org/10.2337/db22-1346-p