Zobrazeno 1 - 5
of 5
pro vyhledávání: '"SPL (S1P lyase)"'
Autor:
Baasanjav Uranbileg, Makoto Kurano, Kuniyuki Kano, Eri Sakai, Junichi Arita, Kiyoshi Hasegawa, Takeshi Nishikawa, Soichiro Ishihara, Hiroharu Yamashita, Yasuyuki Seto, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background In addition to potent agonist properties for sphingosine 1‐phosphate (S1P) receptors, intracellularly, S1P is an intermediate in metabolic conversion pathway from sphingolipids to glycerolysophospholipids (glyceroLPLs). We hypot
Externí odkaz:
https://doaj.org/article/5cd81ea249b54027a2296d0bd8c846ea
Autor:
Christopher Green, Deanna L. Davis, Sarah Spiegel, Michael Maceyka, Usha Mahawar, Clement Oyeniran, Binks W. Wattenberg, Cynthia Weigel, Jason Newton, Briana N. James
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100082-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100082-(2021)
The serine palmitoyltransferase (SPT) complex catalyzes the rate-limiting step in the de novo biosynthesis of ceramides, the precursors of sphingolipids. The mammalian ORMDL isoforms (ORMDL1-3) are negative regulators of SPT. However, the roles of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db4a783bcfe3cd38f08db6299eb2fbf
http://europepmc.org/articles/PMC8167824
http://europepmc.org/articles/PMC8167824
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 151-157 (2015)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The liver is the central organ involved in lipid metabolism. Dyslipidemia and its related disorders, including non-alcoholic fatty liver disease (NAFLD), obesity and other metabolic diseases, are of increasing public health concern due to their incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2081940d075535ab683fd5ac3182d0
Akademický článek
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Autor:
Kwong E; Department of Microbiology and Immunology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA., Li Y; McGuire VA Medical Center, Richmond, VA 23249, USA., Hylemon PB; Department of Microbiology and Immunology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA ; McGuire VA Medical Center, Richmond, VA 23249, USA., Zhou H; Department of Microbiology and Immunology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA ; McGuire VA Medical Center, Richmond, VA 23249, USA.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2015 Mar; Vol. 5 (2), pp. 151-7. Date of Electronic Publication: 2015 Feb 09.