Zobrazeno 1 - 10
of 818
pro vyhledávání: '"SPINK1"'
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundAsparaginase is a critical component of chemotherapy for pediatric acute lymphoblastic leukemia (ALL), but its use is often complicated by asparaginase-associated pancreatitis (AAP). Genetic predispositions, such as variants in the SPINK1 g
Externí odkaz:
https://doaj.org/article/7ab9ffaf00794f10b4dbaaca5a9dbdc7
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Machine learning techniques have been widely used in predicting disease prognosis, including cancer prognosis. One of the major challenges in cancer prognosis is to accurately classify cancer types and stages to optimize early screening and
Externí odkaz:
https://doaj.org/article/7b0893026de94b089566a2748dbd2c0e
Autor:
Piera Bontempo, Cecilia Surace, Lucia Menale, Claudia Alicata, Gemma D’Elia, Anna Cristina Tomaiuolo, Daniele Minervino, Elisa Lorefice, Antonio Novelli
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1278 (2024)
Chronic pancreatitis is often secondary to alcohol abuse, but pancreatitis with no other aetiology is frequently associated with variants in genes encoding proteins related to zymogen granule activation. Our goal was to identify genomic variants in a
Externí odkaz:
https://doaj.org/article/ebbf9e556fe144fc9b4b51769b592eaf
Akademický článek
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Autor:
Susumu Horitani, Masahiro Tsujimae, Arata Sakai, Atsuhiro Masuda, Kae Nagao, Shinya Kohashi, Noriko Inomata, Hisahiro Uemura, Shigeto Masuda, Masanori Gonda, Shohei Abe, Kohei Yamakawa, Shigeto Ashina, Yasutaka Yamada, Takeshi Tanaka, Ryota Nakano, Takashi Kobayashi, Hideyuki Shiomi, Yuzo Kodama
Publikováno v:
Case Reports in Gastroenterology, Vol 17, Iss 1, Pp 55-61 (2023)
When the etiology of pancreatitis cannot be determined despite sufficient investigation, recurrence and progression to chronic pancreatitis often involve genetic mutations. Herein, we describe a case of recurrent pancreatitis with the IVS3+2T>C mutat
Externí odkaz:
https://doaj.org/article/8f4ae9d3024d446e9355f7ee324b75a4
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 265 (2024)
Low efficacy of treatments and chemoresistance are challenges in addressing refractory hepatocellular carcinoma (HCC). SPINK1, an oncogenic protein, is frequently overexpressed in many HCC cases. However, the impact of SPINK1 on HCC treatment resista
Externí odkaz:
https://doaj.org/article/45e37c86b1344592b5c748594e18e21e
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 298 (2024)
Chronic pancreatitis (CP) is an irreversible and progressive inflammation of the pancreas that can involve both pancreatic parenchyma and the pancreatic duct. CP results in morphological changes in the gland in the form of fibrosis and calcification
Externí odkaz:
https://doaj.org/article/5cad0ba42e5b4c61a3dc2fad7c907b7e
Autor:
Samir Al Bashir, Mohammed S. Alorjani, Khalid Kheirallah, Mohammad Al Hamad, Husam K. Haddad, Ahmad Al-Dwairy, Baha A. Bani-Fawwaz, Najla Aldaoud, Omar Halalsheh, Saddam Amawi, Ismail I. Matalka
Publikováno v:
Medicina, Vol 60, Iss 1, p 174 (2024)
Background and Objectives: Prognostic biomarkers in prostate cancer (PCa) include PTEN, ERG, SPINK1, and TFF3. Their relationships and patterns of expression in PCa in developing countries, including Jordan, have not yet been investigated. Materials
Externí odkaz:
https://doaj.org/article/a6d57b0a309d4034b40956b034704683
Akademický článek
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Akademický článek
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