Zobrazeno 1 - 10
of 1 279
pro vyhledávání: '"SPINAL NERVE LIGATION"'
Publikováno v:
陆军军医大学学报, Vol 46, Iss 15, Pp 1740-1750 (2024)
Objective To investigate the effect of minocycline (Mino) on the polarization of types M1/M2 microglia (pro- and anti-inflammatory type) in the spinal dorsal horn of rats with neuropathic pain (NP) induced by spinal nerve ligation (SNL) and its under
Externí odkaz:
https://doaj.org/article/bc8c511b1d4f4942bcb0cd88ece80380
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Gastrodin (GAS), a main bioactive component of the herbal plant, Gastrodia elata Blume, has shown to have beneficial effects on neuroinflammatory diseases such as Alzheimer’s disease in animal studies and migraine in clinical st
Externí odkaz:
https://doaj.org/article/97b8c955f7d444ce810ca1c83be9d58d
Autor:
Jie Quan, Chun Jing He, Ji Yeon Kim, Jin Young Lee, Chang Jae Kim, Young Jae Jeon, Chang Woo Im, Do Kyung Lee, Ji Eun Kim, Hue Jung Park
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1379 (2024)
Neuropathic pain (NP) results from lesions or diseases affecting the peripheral or central somatosensory system. However, there are currently no drugs that are particularly effective in treating this condition. SKI306X is a blend of purified extracts
Externí odkaz:
https://doaj.org/article/9b47aa6f36e2454499a2e8a701394b5b
Autor:
Lili Sun, Jie Zhang, Changshan Niu, Cassandra E. Deering-Rice, Ronald W. Hughen, John G. Lamb, Katherine Rose, Kevin M. Chase, Marysol Almestica-Roberts, Markel Walter, Eric W. Schmidt, Alan R. Light, Baldomero M. Olivera, Christopher A. Reilly
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 68-81 (2023)
Pain is often debilitating, and current treatments are neither universally efficacious nor without risks. Transient receptor potential (TRP) ion channels offer alternative targets for pain relief, but little is known about the regulation or identitie
Externí odkaz:
https://doaj.org/article/6bb12ec7d65448d6a83796dbcdf8242d
Akademický článek
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Akademický článek
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Publikováno v:
Brain Research Bulletin, Vol 188, Iss , Pp 1-10 (2022)
The anterior nucleus of the paraventricular thalamus (aPVT) integrates various synaptic inputs and conveys information to the downstream brain regions for arousal and pain regulation. Recent studies have indicated that the PVT plays a crucial role in
Externí odkaz:
https://doaj.org/article/2c394f84e9c841719f26339c74b780af
Autor:
Fernanda B. de M. Monte, Tadeu L. Montagnoli, Bruno E. Dematté, Fernanda Gubert, Vitória S. Ventura, Jaqueline S. da Silva, Margarete M. Trachez, Rosalia Mendez-Otero, Gisele Zapata-Sudo
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3249 (2023)
Chronic pain presents a major challenge in contemporary medicine, given the limited effectiveness and numerous adverse effects linked to available treatments. Recognizing the potential of the cholinergic pathway as a therapeutic target, the present w
Externí odkaz:
https://doaj.org/article/a69e5748e29c4bdfb2897635522b8b7e
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 370-377 (2022)
High-frequency spinal cord stimulation (HF-SCS) has been established as an effective therapy for neuropathic pain. However, the analgesic mechanisms involved in HF-SCS remain to be clarified. In our study, adult rat neuropathic pain was induced by sp
Externí odkaz:
https://doaj.org/article/472b1034534249c3a86c93d1899354c7
Publikováno v:
Journal of Pain Research, Vol Volume 14, Pp 665-679 (2021)
Xin Jiang,1,* Wenqi Zhao,1,* Tiantian Zhao,2,* Mei Yang,1 Hongbin Yuan,1 Jun Qian,2 Zhenghua Xiang3 1Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Department of General Surgery,
Externí odkaz:
https://doaj.org/article/a08e8f9388bd4c4993bcf9f33f7dedd5