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ROLE OF HIF ACTIVATION IN THE PROTECTION OF CARDIOMYOCYTES FROM DOXORUBICIN TOXICITY

Autor: SPAGNUOLO, ROSALIN DOLORES

Anthracyclines are important and effective anticancer drugs used in the treatment of many adult and children malignancies. Doxorubicin (DOX) is the anthracycline most commonly used in cancer patients but its cardiotoxicity limits its clinical use. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8e806dc88f23b335ac6b1354fe90a8a

Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.

Autor: Ciceri S; Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Montalvão-de-Azevedo R; Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Pediatric Hematology-Oncology Research Program, Research Center (CPQ), Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Tajbakhsh A; Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Medical Genetic and Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Bertolotti A; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Spagnuolo RD; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Boschetti L; Pediatric Oncology Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Capasso M; Department of Pediatric Oncology, Ospedale Santobono-Pausilipon, Naples, Italy., D'Angelo P; Pediatric Hematology and Oncology Unit, ARNAS Civico, Di Cristina e Benfratelli Hospitals, Palermo, Italy., Serra A; Department of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Pediatric Hospital and IRCCS, Rome, Italy., Diomedi-Camassei F; Pathology Unit, Department of Laboratories, Bambino Gesù Pediatric Hospital and IRCCS, Rome, Italy., Meli M; Unit of Pediatric Hematology and Oncology, Department of Clinical and Experimental Medicine, Hospital Policlinico, University of Catania, Catania, Italy., Nantron M; Department of Hematology and Oncology, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Quarello P; Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Turin, Italy., Buccoliero AM; Division of Pathology, Children's Hospital A. Meyer-University of Florence, Florence, Italy., Tamburini A; Hematology Oncology and HSCT Unit, Children's Hospital A.Meyer-University of Florence, Florence, Italy., Ciniselli CM; Bioinformatics and Biostatistics Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Verderio P; Bioinformatics and Biostatistics Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Collini P; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Radice P; Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Spreafico F; Pediatric Oncology Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Perotti D; Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. daniela.perotti@istitutotumori.mi.it.

Publikováno v: Cancer gene therapy [Cancer Gene Ther] 2021 Sep; Vol. 28 (9), pp. 1016-1024. Date of Electronic Publication: 2020 Dec 06.