Development of noninvasive biomarkers of response to proteasome inhibitor therapy (ixazomib) by imaging disrupted protein homeostasis in mouse models of solid tumors

Autor: SP Johnson, Rajiv Ramasawmy, Chattopadhyay N, Simon Walker-Samuel, Zhu Y, Mark F. Lythgoe, Bradley D, Taylor, Alasdair J. Gibb, Xavier Golay, RB Pedley

With clinically-approved proteasome inhibitors now a standard of care for multiple myeloma, and increasing interest in their use in solid tumors, methods for monitoring therapeutic response in vivo are critically required. Here, we show that tumor pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a703b4022942c4f880f2a95211fa3c

The effect of imatinib therapy on tumour cycling hypoxia, tissue oxygenation and vascular reactivity

Autor: SP Johnson, Simon Walker-Samuel, Mark F. Lythgoe, Rajiv Ramasawmy, Miguel R. Gonçalves, R. Barbara Pedley

Publikováno v: Wellcome Open Research. 2:38

Background: Several biomedical imaging techniques have recently been developed to probe hypoxia in tumours, including oxygen-enhanced (OE) and blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI). These techniques have strong potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0935cd8430ded704e5cb75da3bfdb21
https://doi.org/10.12688/wellcomeopenres.11715.1

Abstract A08: Investigating tumor vasculature development and the effects of OXi4503 by non-invasive photoacoustic imaging

Autor: Edward Z. Zhang, Ollie Ogunlade, Rosamund Barbara Pedley, Mark F. Lythgoe, Paul C. Beard, SP Johnson

Publikováno v: Cancer Research. 75:A08-A08

Vasculature-targeted cancer therapies, such as vascular disrupting or anti-angiogenic agents, interact directly with tumor blood vessels. Direct longitudinal assessment of vascular response, as opposed to indirect measures of tumor volume, would aid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0084606ab472bdfb0f322b031dabb27
https://doi.org/10.1158/1538-7445.chtme14-a08

Minding the gap: a sex difference in young infants' mental rotation through thirty degrees of arc.

Autor: Moore DS; Psychology Field Group, Pitzer College, Claremont, CA, United States.; Center for Advanced Study in the Behavioral Sciences, Stanford University, Stanford, CA, United States., Moore DM; Center for Advanced Study in the Behavioral Sciences, Stanford University, Stanford, CA, United States.; Department of Psychology, New Mexico State University, Las Cruces, NM, United States., Johnson SP; Department of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.

Publikováno v: Frontiers in psychology [Front Psychol] 2024 Sep 13; Vol. 15, pp. 1415651. Date of Electronic Publication: 2024 Sep 13 (Print Publication: 2024).

Infants' Preference for ID Speech in Face and Voice Extends to a Non-Native Language.

Autor: Birulés J; Laboratoire de Psychologie et NeuroCognition, UMR 5105, University Grenoble Alpes, Grenoble, France., Méary D; Laboratoire de Psychologie et NeuroCognition, UMR 5105, University Grenoble Alpes, Grenoble, France., Fort M; Laboratoire de Psychologie et NeuroCognition, UMR 5105, University Grenoble Alpes, Grenoble, France.; Centre de Recherche en Neurosciences de Lyon, UMR 5292, Université Lyon 1, Lyon, France., Hojin K; Department of Quantitative Theory and Methods, Emory University, Atlanta, Georgia, USA., Johnson SP; Department of Psychology, University of California, Los Angeles, California, USA., Pascalis O; Laboratoire de Psychologie et NeuroCognition, UMR 5105, University Grenoble Alpes, Grenoble, France.

Publikováno v: Infancy : the official journal of the International Society on Infant Studies [Infancy] 2025 Jan-Feb; Vol. 30 (1), pp. e12639.