Zobrazeno 1 - 10
of 20
pro vyhledávání: '"SOXB1 Transcription Factor"'
Autor:
Therese Riedemann, Sven Falk, Barbara Treutlein, J. Gray Camp, Tobias Gerber, Andrej Smiyakin, Magdalena Götz, Christian Schichor, Angela Garding, Agnieska Brazovskaja, Vijay K. Tiwari, Abhijeet Pataskar, Wenqiang Fan, Benedikt Berninger, Malgorzata Gac-Santel, Marisa Karow, Jorge Kageyama, Antonella Casamassa
Publikováno v:
Karow, M, Camp, J G, Falk, S, Gerber, T, Pataskar, A, Gac-Santel, M, Kageyama, J, Brazovskaja, A, Garding, A, Fan, W, Riedemann, T, Casamassa, A, Smiyakin, A, Schichor, C, Götz, M, Tiwari, V K, Treutlein, B & Berninger, B 2018, ' Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program ', Nature Neuroscience, vol. 21, no. 7, pp. 932–940 . https://doi.org/10.1038/s41593-018-0168-3
Nat. Neurosci. 21, 932–940 (2018)
Nature Neuroscience
Nature Neuroscience, 21 (7)
Nature neuroscience
Nat. Neurosci. 21, 932–940 (2018)
Nature Neuroscience
Nature Neuroscience, 21 (7)
Nature neuroscience
Ectopic expression of defined transcription factors can force direct cell-fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled successful reprogramming of various somatic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1946f77c6a169a8af4c30f18efafe13f
https://kclpure.kcl.ac.uk/ws/files/97577878/Karow_et_al_final_version.pdf
https://kclpure.kcl.ac.uk/ws/files/97577878/Karow_et_al_final_version.pdf
Autor:
Umberto Galderisi, Paola Mariani, Alfredo Santinelli, Tiziana Squillaro, Antonio Giordano, Andrea Marcellusi, Mauro Finicelli, Giovanni Benedetti, Barbara Pistilli, Luciano Latini
Publikováno v:
Oncotarget
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
// Mauro Finicelli 1,* , Giovanni Benedetti 2,* , Tiziana Squillaro 1 , Barbara Pistilli 2 , Andrea Marcellusi 3 , Paola Mariani 4 , Alfredo Santinelli 5 , Luciano Latini 2 , Umberto Galderisi 6,7 , Antonio Giordano 1,6 1 Human Health Foundation, Spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab7d19a911a93509766f7bc64954436
https://doi.org/10.18632/oncotarget.1936
https://doi.org/10.18632/oncotarget.1936
Autor:
Silvia Bonanno, Claudia Barzago, Fulvio Baggi, Dimos Kapetis, Stefania Marcuzzo, Pia Bernasconi, Nicole Kerlero de Rosbo, Renato Mantegazza, Paola Cavalcante
Publikováno v:
Experimental Neurology. 253:91-101
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motoneuron loss in the CNS. In G93A-SOD1 mice, motoneuron degeneration is associated with proliferative restorative attempts of ependymal stem prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dfc9c1e7db2689e280d64c49406adb
https://doi.org/10.1016/j.expneurol.2013.12.007
https://doi.org/10.1016/j.expneurol.2013.12.007
Autor:
Nikolay Zinin, Silvia K. Nicolis, Thomas Müller, Carmen Birchmeier, Satish Srinivas Kitambi, Patrik Ernfors, Albert Blanchart, Ueli Suter, Alessandro Furlan, Sergi Aranda, Francois Lallemend, Yoshiko Takahashi, Ismail Zaitoun, Rebecca Favaro, Igor Adameyko, Moritz Lübke
Publikováno v:
Development (Cambridge England)
Development; Vol 139
Development; Vol 139
The cellular origin and molecular mechanisms regulating pigmentation of head and neck are largely unknown. Melanocyte specification is controlled by the transcriptional activity of Mitf, but no general logic has emerged to explain how Mitf and progen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6552f3e934ef2b95942b0e3ad31c7a0b
https://doi.org/10.1242/dev.065581
https://doi.org/10.1242/dev.065581
Autor:
Silvia K. Nicolis, Anna Ferri, Rebecca Favaro, Sergio Ottolenghi, Menella Valotta, Claudio Giachino, Cesare Lancini, Verdon Taylor, Jessica Mariani, Elisa Latorre, Valentina Tosetti
Publikováno v:
Nature Neuroscience. 12:1248-1256
Neural stem cells (NSCs) are controlled by diffusible factors. The transcription factor Sox2 is expressed by NSCs and Sox2 mutations in humans cause defects in the brain and, in particular, in the hippocampus. We deleted Sox2 in the mouse embryonic b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6410b9aacedae1a3c21a00a89441ce84
https://doi.org/10.1038/nn.2397
https://doi.org/10.1038/nn.2397
Autor:
Maurizio Cavallaro, Elisa Latorre, Silvia DeBiasi, Antonella Ronchi, Francesca Gullo, Silvia Brunelli, Jessica Mariani, Rebecca Favaro, Menella Valotta, Silvia K. Nicolis, Enzo Wanke, Laura Spinardi, Roberta Caccia, Cesare Lancini, Sergio Ottolenghi
Publikováno v:
Development. 135:541-557
The transcription factor Sox2 is active in neural stem cells, and Sox2`knockdown' mice show defects in neural stem/progenitor cells in the hippocampus and eye, and possibly some neurons. In humans, heterozygous Sox2 deficiency is associated with eye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6eecfdd8ccb222202446ed6fcc5ba1d
https://doi.org/10.1242/dev.010801
https://doi.org/10.1242/dev.010801
Autor:
Maria Teresa Dell’Anno, Vania Broccoli, Raul R. Gainetdinov, Damiana Leo, Dimitra Alexopoulou, Gabriele Lignani, Fabio Benfenati, Marta Orlando, Latefa Yekhlef, Luca Massimino, Ernesto Ciabatti, Alessandro Sessa, Michèle Studer, Serena Giannelli, Lucian Medrihan, Silvio Sacchetti, Gaia Colasante, Alicia Rubio, Andreas Dahl, Stefano Taverna, Massimiliano Caiazzo
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 2015, 17 (6), pp.719-34
Cell Stem Cell, 2015, 17 (6), pp.719-34
International audience; Transplantation of GABAergic interneurons (INs) can provide long-term functional benefits in animal models of epilepsy and other neurological disorders. Whereas GABAergic INs can be differentiated from embryonic stem cells, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f20a4fb51498e719227fd2e7341402f
https://hal.archives-ouvertes.fr/hal-01255231
https://hal.archives-ouvertes.fr/hal-01255231
Autor:
Lidia Pérez, Robin Lovell-Badge, Silvia K. Nicolis, Larysa H. Pevny, Ariel A. Avilion, Nigel Vivian
Publikováno v:
Genes & Development. 17:126-140
Each cell lineage specified in the preimplantation mammalian embryo depends on intrinsic factors for its development, but there is also mutual interdependence between them. OCT4 is required for the ICM/epiblast lineage, and at transient high levels f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b8305bd4c48fc8267d1326b1cb15e2
https://doi.org/10.1101/gad.224503
https://doi.org/10.1101/gad.224503
Autor:
Gaetano Finocchiaro, Federica Pisati, Irene Appolloni, Sergio Ottolenghi, Serena Pellegatta, Eleonora Gambini, Alexandra Badiola Sanga, Pierfrancesco Pagella, Silvia K. Nicolis, Paolo Malatesta, Maria Foti, Rebecca Favaro
The stem cell–determining transcription factor Sox2 is required for the maintenance of normal neural stem cells. In this study, we investigated the requirement for Sox2 in neural cancer stem-like cells using a conditional genetic deletion mutant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde6b39d2e4a710fc5713065fd0b9c23
http://hdl.handle.net/11567/696196
http://hdl.handle.net/11567/696196
Autor:
Elena Nasonova, S. Luft, Onetsine Arrizabalaga, Sylvia Ritter, Marco Durante, Alexander Helm, Diana Pignalosa
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 760
The risk of radiation exposure during embryonic development is still a major problem in radiotoxicology. In this study we investigated the response of the murine embryonic stem cell (mESC) line D3 to two radiation qualities: sparsely ionizing X-rays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095357762215f72f8cba0cd4992795a8
https://pubmed.ncbi.nlm.nih.gov/24397998
https://pubmed.ncbi.nlm.nih.gov/24397998