Zobrazeno 1 - 10
of 19 706
pro vyhledávání: '"SONIC HEDGEHOG"'
Autor:
Andrew Awuah Wireko, Adam Ben-Jaafar, Jonathan Sing Huk Kong, Krishitha Meenu Mannan, Vivek Sanker, Sophie-Liliane Rosenke, Allswell Naa Adjeley Boye, Princess Afia Nkrumah-Boateng, Jeisun Poornaselvan, Muhammad Hamza Shah, Toufik Abdul-Rahman, Oday Atallah
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-22 (2024)
Abstract CNS tumours encompass a diverse group of neoplasms with significant morbidity and mortality. The SHH signalling pathway plays a critical role in the pathogenesis of several CNS tumours, including gliomas, medulloblastomas and others. By infl
Externí odkaz:
https://doaj.org/article/127fd4a474354ac48f7338d83df8193b
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 10, Pp 01-05 (2024)
Odontogenic tumours, derived from the epithelial, ectomesenchymal, and/or mesenchymal elements of the tooth-forming apparatus, constitute a heterogeneous group of lesions that include both benign and malignant neoplasms with metastatic capabilities.
Externí odkaz:
https://doaj.org/article/119b00b3d5a746e4be46a0f1f00b10d8
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4565-4584 (2024)
Ziyan Zhong,1,* Jian Liu,2,* Yan Luo,1 Mei Wu,1 Feng Qiu,1 Hongqing Zhao,1 Yang Liu,1 Yajing Wang,3 Hongping Long,2 Lei Zhao,4 Yuhong Wang,1 Yuanshan Han,2 Pan Meng1 1Science & Technology Innovation Center, Hunan University of Chinese Medicin
Externí odkaz:
https://doaj.org/article/1941eb8ffb2c4044a6154f25d0fe95c3
Autor:
Mohamed Tail, Hao Zhang, Guoli Zheng, Anna-Kathrin Harms, Maryam Hatami, Thomas Skutella, Karl Kiening, Andreas Unterberg, Klaus Zweckberger, Alexander Younsi
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Sonic Hedgehog (Shh), extensively researched for its role in early neurogenesis and brain development, has recently been recognized for its neuroprotective potential following neuronal injuries. This study examines the immediate i
Externí odkaz:
https://doaj.org/article/997d4ce093d346518cc461975b672c13
Autor:
XU Yao, LI Wenjin
Publikováno v:
口腔疾病防治, Vol 32, Iss 9, Pp 709-714 (2024)
The source and process of mandible development are significantly different from those of other bones in the body, and abnormal development can lead to various bone-related diseases, seriously affecting the quality of life of patients. In recent years
Externí odkaz:
https://doaj.org/article/c74b59bc99d44acbbe227e66a8e5d979
Autor:
Kuang-Yao Chen, Chien-Ju Cheng, Yuan-Ting Chang, Yi-Hsuan Lin, Yi-Hao Huang, Sheng-Yu Lin, Lian-Chen Wang, Kai-Yuan Jhan, Cheng-Hsun Chiu
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 26, Iss , Pp 100560- (2024)
Autophagy is a vital cellular process responsible for digesting various cytoplasmic organelles. This process plays a crucial role in maintaining cell survival and homeostasis, especially under conditions that cause nutrient deficiency, cellular damag
Externí odkaz:
https://doaj.org/article/f22563578e264069b6ddde5dc4b9bf4a
Autor:
Cong Wang, Zhiwei Lai, Huishi Tan, Hua Zhang, Lishan Tan, Qingyun Luo, Sanmu Li, Zibo Xiong, Guang Yang, Zuying Xiong
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39332- (2024)
Backgrounds: Heart failure (HF) is characterized by progressive cardiac hypertrophy and fibrosis, yet the underlying pathological mechanisms remain unclear. Exosomes are pivotal in cellular communication and are key signaling carriers in HFs. This st
Externí odkaz:
https://doaj.org/article/ef2c5793b51541888c7aca0546c95fd5
Autor:
Julei Zhang, Zeliang He, Chenlu Xiong, Yuanyuan Yao, Chengliang Zhang, Wende Yao, Sihan Yang, Xiaodong Li, Yan Han
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Excessive scar formation such as hypertrophic scars and keloids, resulting from trauma or surgical procedures, present a widespread concern for causing disfigurement, discomfort, and functional limitations. Macrophages play pivotal roles in
Externí odkaz:
https://doaj.org/article/02d7d91653e2485284f0c9141dcd3865
Autor:
Antonio Del Casale, Martina Nicole Modesti, Giovanna Gentile, Cecilia Guariglia, Stefano Ferracuti, Maurizio Simmaco, Marina Borro
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5322-5336 (2024)
Among the pathophysiological correlates of schizophrenia, recent research suggests a potential role for the Hedgehog (Hh) signalling pathway, which has been traditionally studied in embryonic development and oncology. Its dysregulation may impact bra
Externí odkaz:
https://doaj.org/article/828cb15626a7411da95dc2fc689b9de0
Autor:
Carlo Berrino, Aadilah Omar
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5397-5419 (2024)
The Sonic Hedgehog (Shh) signalling pathway plays a critical role in normal development and tissue homeostasis, guiding cell differentiation, proliferation, and survival. Aberrant activation of this pathway, however, has been implicated in the pathog
Externí odkaz:
https://doaj.org/article/46abf58053ee4560a0b16f66088da405