Zobrazeno 1 - 10
of 18
pro vyhledávání: '"SOFIE HAEDERSDAL"'
Publikováno v:
Nature Reviews Endocrinology. 19:321-335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798706a5a2bb0e2a3c59532fceefb868
https://doi.org/10.1038/s41574-023-00817-4
https://doi.org/10.1038/s41574-023-00817-4
Autor:
HENRIK MAAGENSEN, SOFIE HAEDERSDAL, JESPER KROGH, TORBEN HANSEN, FILIP K. KNOP, TINA VILSBØLL
Publikováno v:
Diabetes. 71
Mutations in hepatocyte nuclear factor 1-alpha (HNF1A) cause HNF1A-diabetes (or maturity-onset diabetes of the young type 3 (MODY3)) . Treatment of HNF1A-diabetes is primarily based on sulphonylureas (SU) and secondarily insulins, glucagon-like pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5acb9816440b47b56fb867f257f6257
https://doi.org/10.2337/db22-182-or
https://doi.org/10.2337/db22-182-or
Autor:
Elisabeth Nielsen-Hannerup, Filip K. Knop, Tina Vilsbøll, Sofie Hædersdal, Henrik Maagensen, Gerrit van Hall, Asger Lund, Jens J. Holst
Publikováno v:
Diabetes
Sodium–glucose cotransporter 2 inhibitors (SGLT2i) effectively lower plasma glucose (PG) concentration in patients with type 2 diabetes, but studies have suggested that circulating glucagon concentrations and endogenous glucose production (EGP) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aff035e14f977810a8bf0bf1699dc74
https://doi.org/10.2337/db20-0369
https://doi.org/10.2337/db20-0369
Autor:
Kathrine Rose, Filip K. Knop, Nina L. Hansen, Torben Hansen, Sofie Hædersdal, Tina Vilsbøll, Alexander S. Christensen, Jens J. Holst, Heidi Storgaard
Publikováno v:
Diabetes
Sulfonylureas (SUs) provide an efficacious first-line treatment in patients with hepatocyte nuclear factor 1α (HNF1A) diabetes, but SUs have limitations due to risk of hypoglycemia. Treatment based on the incretin hormones glucose-dependent insulino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb4da958f9030f238f2cd9e34f267b1
https://doi.org/10.2337/db20-0074
https://doi.org/10.2337/db20-0074
Autor:
Dongyan Zhang, Yuichi Nozaki, Gerald I. Shulman, Graeme F. Mason, Xian-Man Zhang, Kitt Falk Petersen, Sofie Haedersdal, Varman T. Samuel, Gina M. Butrico, Douglas L. Rothman, Rachel J. Perry, Gary W. Cline, Abudukadier Abulizi, Max C. Petersen, Daniel F. Vatner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Hepatic glycogen synthesis plays a critical role in maintaining normal glucose homeostasis; however, the rate-controlling step regulating this process is unknown. Applying metabolic control analysis in vivo, we show that the regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1632ebe3621a1bf0aef3593b54a090f
https://doi.org/10.1073/pnas.1921694117
https://doi.org/10.1073/pnas.1921694117
Autor:
Sofie Hædersdal, Asger Lund, Henrik Maagensen, Elisabeth Nielsen-Hannerup, Lærke S Gasbjerg, Mette M Rosenkilde, Julie L Forman, Gerrit van Hall, Jens J Holst, Filip K Knop, Tina Vilsbøll
Publikováno v:
European journal of endocrinology. 186(2)
Objective Type 2 diabetes (T2D) pathophysiology includes fasting and postprandial hyperglucagonemia, which has been linked to hyperglycemia via increased endogenous glucose production (EGP). We used a glucagon receptor antagonist (LY2409021) and stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4b879d2fc99a5c76d14d7a3c9b55c2
https://pubmed.ncbi.nlm.nih.gov/34863038
https://pubmed.ncbi.nlm.nih.gov/34863038
Autor:
Yina Ma, Leigh Goedeke, Lawrence H. Young, Gerald I. Shulman, Katrine D. Galsgaard, Jianying Dong, Gary W. Cline, Xian-Man Zhang, Sofie Hædersdal, Jiasheng Zhang, Nicole Guerrera, Ji Eun Lee, Rachel J. Perry, Xiaoyue Hu
Publikováno v:
Diabetes. 70
Recent clinical outcome studies demonstrate that SGLT2 inhibitors (i) significantly reduce major adverse cardiovascular events and heart failure in patients with and without type 2 diabetes; however, the mechanisms by which SGLT2i exert their cardiov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8a2bb7cdb7d27940ecd0341906b298
https://doi.org/10.2337/db21-323-or
https://doi.org/10.2337/db21-323-or
Autor:
Tina Vilsbøll, Filip K. Knop, Jens J. Holst, Gerrit van Hall, Henrik Maagensen, Elisabeth Nielsen-Hannerup, Asger Lund, Sofie Hædersdal, Ada Admin
Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) effectively lower plasma glucose (PG) concentration in patients with type 2 diabetes, but studies suggest that circulating glucagon concentrations and endogenous glucose production (EGP) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2afd85fad437500735bda3100017bb
https://doi.org/10.2337/figshare.13010123
https://doi.org/10.2337/figshare.13010123
Autor:
Tina Vilsbøll, Filip K. Knop, Torben Hansen, Jens J. Holst, Marta Seghieri, Julie L. Forman, Ulla Kampmann, Heidi Storgaard, Julie Støy, Sofie Hædersdal, Alexander S. Christensen
OBJECTIVE Sulfonylureas are first-line treatment of hepatocyte nuclear factor 1-alpha (HNF1A)-diabetes [maturity onset diabetes of the young type 3], but many patients do not achieve optimal glycemic control without episodes of hypoglycemia. We inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006c9840282c59598c95067e03cf019c
https://doi.org/10.2337/figshare.12515230
https://doi.org/10.2337/figshare.12515230
Autor:
Tina Vilsbøll, Filip K. Knop, Torben Hansen, Jens J. Holst, Nina L. Hansen, Kathrine Rose, Heidi Storgaard, Sofie Hædersdal, Alexander S. Christensen, Ada Admin
Sulfonylureas (SUs) provide an efficacious first-line treatment in patients with hepatocyte nuclear factor 1-alpha (HNF1A)-diabetes, but SUs have limitations due to risk of hypoglycemia. Treatment based on the incretin hormones, glucose-dependent ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab5119769c4e2bd16b05f5fbb5e3b13
https://doi.org/10.2337/figshare.12410447
https://doi.org/10.2337/figshare.12410447