Zobrazeno 1 - 10
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pro vyhledávání: '"SODIUM CURRENT"'
Autor:
Elena Lilliu, Benjamin Hackl, Eva Zabrodska, Stefanie Gewessler, Tobias Karge, Jessica Marksteiner, Jakob Sauer, Eva M. Putz, Hannes Todt, Karlheinz Hilber, Xaver Koenig
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
Alterations in ion channel expression and function known as “electrical remodeling” contribute to the development of hypertrophy and to the emergence of arrhythmias and sudden cardiac death. However, comparing current density values – an electr
Externí odkaz:
https://doaj.org/article/e86277c805824e5282c08c78530939da
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 9, p 313 (2024)
Brugada syndrome (BrS) is an inheritable cardiac arrhythmogenic disease, associated with an increased risk of sudden cardiac death. It is most common in males around the age of 40 and the prevalence is higher in Asia than in Europe and the United Sta
Externí odkaz:
https://doaj.org/article/4e65a2cb49694cefb66aea8330f3e9d2
Autor:
Jun Fan, Shao-hua Wang, Li-li Cao, Wei-jie Li, Shao-xi Sun, Shao-ling Luo, Yi-chao Pan, Wen-liang Tan, Tian-yuan Wu, Zhen Liu, Bing-bo Yu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThe Scn3b gene encodes for Navβ3, a pivotal regulatory subunit of the fast sodium channel in cardiomyocytes. However, its mutation status in the Chinese population suffering from Brugada Syndrome (BrS) has not been characterized, and the c
Externí odkaz:
https://doaj.org/article/aa299c982d4549e687353c344cc0a8fc
Autor:
Sandra Raposo-García, Ana M. Botana, Verónica Rey, Celia Costas, Luis Rodríguez-Santos, M. Carmen Louzao, Carmen Vale, Luis M. Botana
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25338- (2024)
Paralytic shellfish poisoning is a foodborne illness that typically derive from the consumption of shellfish contaminated with saxitoxin-group of toxins produced by dinoflagellates of the genus Gymnodinium, Alexandrium and Pyrodinium. N-sulfocarbamoy
Externí odkaz:
https://doaj.org/article/48da08e2e9b54b4ebe56b1fd524b2d58
Autor:
Arie O. Verkerk, Ronald Wilders
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Human-induced stem cell-derived cardiomyocytes (hiPSC-CMs) are a valuable tool for studying development, pharmacology, and (inherited) arrhythmias. Unfortunately, hiPSC-CMs are depolarized and spontaneously active, even the working cardiomyocyte subt
Externí odkaz:
https://doaj.org/article/feee9de844df42e697c94b9a90c74737
Autor:
Giovanna Nasilli, Arie O. Verkerk, Molly O’Reilly, Loukia Yiangou, Richard P. Davis, Simona Casini, Carol Ann Remme
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1212 (2024)
A sodium current (INa) reduction occurs in the setting of many acquired and inherited conditions and is associated with cardiac conduction slowing and increased arrhythmia risks. The sodium channel blocker mexiletine has been shown to restore the tra
Externí odkaz:
https://doaj.org/article/fe7447100f724815a62f685b1a775531
Publikováno v:
Physiological Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Ventricular repolarization shows notable sex‐specificity, with female sex being associated with longer QT‐intervals in electrocardiography irrespective of the species studied. From a clinical point of view, women are at a greater risk fo
Externí odkaz:
https://doaj.org/article/dd2c5041ffbc4792a128c46f75d32e9b