Zobrazeno 1 - 10
of 4 925
pro vyhledávání: '"SOCS3"'
Autor:
La Manna S, Cugudda A, Mercurio FA, Leone M, Fortuna S, Di Natale C, Lagreca E, Netti PA, Panzetta V, Marasco D
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7237-7251 (2024)
Sara La Manna,1 Alessia Cugudda,1 Flavia Anna Mercurio,2 Marilisa Leone,2 Sara Fortuna,3 Concetta Di Natale,4 Elena Lagreca,4 Paolo Antonio Netti,4 Valeria Panzetta,4 Daniela Marasco1 1Department of Pharmacy, CIRPEB: Research Center on Bioactive Pept
Externí odkaz:
https://doaj.org/article/26a9d8af82ec4c09bbe010b329157dc6
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5668-5681 (2024)
Based on the analgesic and anti-inflammatory effects of clonidine in previous studies, we hypothesized that clonidine could accelerate wound healing in rats by regulating the expression of related cytokines. In this study, the wound healing effect of
Externí odkaz:
https://doaj.org/article/59b18d334d7448849f09edb76bce668b
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-16 (2024)
Abstract Background Diabetic nephropathy (DN) is a life-threatening renal disease and needs urgent therapies. Wogonin is renoprotective in DN. This study aimed to explore the mechanism of how wogonin regulated high glucose (HG)-induced renal cell inj
Externí odkaz:
https://doaj.org/article/57a359c3a72c4acaae18284da3c85cb4
Autor:
Ritasha Sawoo, Biswadev Bishayi
Publikováno v:
Immunobiology, Vol 229, Iss 5, Pp 152840- (2024)
Due to the urgent need to create appropriate treatment techniques, which are currently unavailable, LPS-induced sepsis has become a serious concern on a global scale. The primary active component in the pathophysiology of inflammatory diseases such a
Externí odkaz:
https://doaj.org/article/ca4848d3552e4b7ab693e43fa836c1ed
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Background Polycystic ovary syndrome (PCOS) is a frequent and complicated endocrine disease that remains a major reason for infertility. Bushenhuoluo Decotion (BSHLD) has been validated to exhibit curative effects on PCOS. This study was aim
Externí odkaz:
https://doaj.org/article/0067ad93c6fc4cddaa57182a57489bcb
Autor:
You Chen, Huazhi Chen, Shuaiwei Ren, Yangfan Xiao, Shuaichao Tao, Jiamei Liu, Xiaoqin Yuan, Xinhua Chen, Yinnan Mu
Publikováno v:
Water Biology and Security, Vol 3, Iss 3, Pp 100270- (2024)
Suppressors of cytokine signaling (SOCS) proteins are important regulators of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Within the SOCS family, SOCS3 is one of the most potent inhibitors of cytokine signali
Externí odkaz:
https://doaj.org/article/0a9a9fd83864416db93a9a4684acd6b3
Autor:
Ning Song, Cunxia Ma, Yuzhu Guo, Shuangshuang Cui, Shihao Chen, Zhi Chen, Yinghui Ling, Yunhai Zhang, Hongyu Liu
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
The suppressor of cytokine signaling 3 (SOCS3) is a key signaling molecule that regulates milk synthesis in dairy livestock. However, the molecular mechanism by which SOCS3 regulates lipid synthesis in goat milk remains unclear. This study aimed to s
Externí odkaz:
https://doaj.org/article/6abbe5ffad6148bf8fe23d5387ec318b
Autor:
Jie Peng, Yawen Gu, Jiang Liu, Hao Yi, Dong Ruan, Haoyu Huang, Yuan Shu, Zhen Zong, Rui Wu, Hui Li
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30020- (2024)
Background: Gout is the most common inflammatory arthritis in adults. Gout is an arthritic disease caused by the deposition of monosodium urate crystal (MSU) in the joints, which can lead to acute inflammation and damage adjacent tissue. Hyperuricemi
Externí odkaz:
https://doaj.org/article/acc31116d1b0414fa7c02c385b4a87d3
Autor:
Wen Fan, Chong Liu, Dacai Chen, Chenjie Xu, Xiuting Qi, Ailin Zhang, Xuexian Zhu, Yujie Liu, Lei Wang, Lanxiang Hao, Wen-Tao Liu, Liang Hu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Gout pain seriously affects the quality of patients' life. There is still no effective treatment. The inflammatory response is the main mechanism of gout. Here, we found that ozone can reduce the inflammatory reaction in the joint
Externí odkaz:
https://doaj.org/article/eabca00408ea44018bcb46668890f8cc
Autor:
Xun Li, Qi Fu, Mingtian Zhong, Yihao Long, Fengyun Zhao, Yanni Huang, Zizhu Zhang, Min Wen, Kaizhao Chen, Rongqing Chen, Xiaodong Ma
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102136- (2024)
Autism is a widespread neurodevelopmental disorder. Although the research on autism spectrum disorders has been increasing in the past decade, there is still no specific answer to its mechanism of action and treatment. As a pro-inflammatory microRNA,
Externí odkaz:
https://doaj.org/article/9d7b720f73fc4352bc83eecadb2d5637