Zobrazeno 1 - 10
of 167
pro vyhledávání: '"SOC channels"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7377 (2022)
Solid tumours are characterised by an altered microenvironment (TME) from the physicochemical point of view, displaying a highly hypoxic and acidic interstitial fluid. Hypoxia results from uncontrolled proliferation, aberrant vascularization and alte
Externí odkaz:
https://doaj.org/article/07d48d89a2ca4693a2f80ccd2ef53327
Autor:
Jon Andoni Sánchez, Amparo Alfonso, Marta Leirós, Eva Alonso, Mostafa E. Rateb, Marcel Jaspars, Wael E. Houssen, Rainer Ebel, Luís M. Botana
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 2, Pp 779-792 (2015)
Background/Aims: The effect of four secondary metabolites isolated from sponge Spongionella, gracilins H, A, L and tetrahydroaplysulphurin-1 on Calcium ion (Ca2+) fluxes were studied in SH-SY5Y neuroblastoma cells. Methods and Results: These compound
Externí odkaz:
https://doaj.org/article/4285f10d124c485292b98d8dba1c3589
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:996-1006
Background Thromboxane A2 (TXA2 ) participates in many pathophysiological processes of coronary artery disease. However, its mechanism of TXA2 -induced contraction in the coronary artery remains to be clarified. Methods Multi Myograph System was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4ae3984f5c10b692c82c40d078e5d7
https://doi.org/10.1111/1440-1681.13502
https://doi.org/10.1111/1440-1681.13502
Autor:
Shamin Rahimi, Tengteng Zhao, Ayako Makino, Marisela Rodriguez, Angela Harrington, Shanshan Song, Patricia A. Thistlethwaite, Aleksandra Babicheva, Ramon J. Ayon, Francesca Balistrieri, John Y.-J. Shyy, Jason X.-J. Yuan
Publikováno v:
American Journal of Physiology-Cell Physiology. 318:C954-C968
The increase in cytosolic Ca2+ concentration ([Ca2+]cyt) and upregulation of calcium-sensing receptor (CaSR) and stromal interaction molecule 2 (STIM2) along with inhibition of voltage-gated K+ (KV) channels in pulmonary arterial smooth muscle cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c18cc62f8e857b3a055830db6c5f093
https://doi.org/10.1152/ajpcell.00487.2019
https://doi.org/10.1152/ajpcell.00487.2019
Publikováno v:
Folia Pharmacologica Japonica. 155:230-235
Pulmonary arterial hypertension (PAH) is a progressive and lethal disease of the pulmonary artery. The pathogenesis of PAH is mainly sustained vasoconstriction and vascular remodeling of the pulmonary artery. These pathogeneses cause progressive elev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f679eb6eda893e00a6a8fae5e8a0ec8
https://doi.org/10.1254/fpj20001
https://doi.org/10.1254/fpj20001
Autor:
Jean-William Dupuy, Karla Alvarez-Valadez, Alexis Groppi, Claire Lescoat, Jenifer Trepiana, Guido Kroemer, Pierre Vacher, Faten Merhi, Pierre Soubeyran, Mojgan Djavaheri-Mergny
Publikováno v:
Cells
Cells, MDPI, 2021, 10 (12), pp.3364. ⟨10.3390/cells10123364⟩
Cells, 2021, 10 (12), pp.3364. ⟨10.3390/cells10123364⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Cells, Vol 10, Iss 3364, p 3364 (2021)
Cells; Volume 10; Issue 12; Pages: 3364
Cells, MDPI, 2021, 10 (12), pp.3364. ⟨10.3390/cells10123364⟩
Cells, 2021, 10 (12), pp.3364. ⟨10.3390/cells10123364⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Cells, Vol 10, Iss 3364, p 3364 (2021)
Cells; Volume 10; Issue 12; Pages: 3364
Calcium ions (Ca2+) play important and diverse roles in the regulation of autophagy, cell death and differentiation. Here, we investigated the impact of Ca2+ in regulating acute promyelocytic leukemia (APL) cell fate in response to the anti-cancer ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e733dfe52eddf5318e41b0dc4481da02
https://hal.archives-ouvertes.fr/hal-03457279
https://hal.archives-ouvertes.fr/hal-03457279
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 7, Iss 5, Pp 62-67 (2008)
Aim. To investigate the effects of an anti-ischemic medication trimetazidine on Са2+ ion metabolism in human leukocyte and monocyte precursors – HL-60 promyelocytes.Material and methods. HL-60 cells were cultivated in vitro. Changes in intracellu
Externí odkaz:
https://doaj.org/article/0cef02cebf0c4f449d7de0b8bded009f
Autor:
Masayoshi Sakakura, Carlos G. Vanoye, Jun Li, Malathi Narayan, Charles R. Sanders, Bruce D. Carter, Rose M. Follis, Alexandra J. Trevisan
Publikováno v:
J Biol Chem
Charcot-Marie-Tooth (CMT) disease is a peripheral neuropathy associated with gene duplication and point mutations in the peripheral myelin protein 22 (PMP22) gene. However, the role of PMP22 in Schwann cell physiology and the mechanisms by which PMP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a169537ebc50b54f06ab945631d22ff
https://doi.org/10.1074/jbc.ra118.006248
https://doi.org/10.1074/jbc.ra118.006248
Autor:
Qiu-Xiong Lin, Ji-Jin Lin, Fang Rao, Xin-Wen Huang, Zhi-Ling Zhou, Lin Liu, Fei-Hong Lian, Min Yang, Zhi-Xin Shan, Hui Yang, Sui Jiang, Meng-Zhen Zhang, Chun-Yu Deng, Su-Juan Kuang
Publikováno v:
Journal of Vascular Research. 56:191-203
Background: Ca2+ plays an important role in the regulation of vasoconstriction. Ca2+ signaling is regulated by a number of Ca2+-handling proteins. However, whether differences in Ca2+ handling affect the regulation of vasoconstriction in different ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4217994c4eac963f8248a7bd4ae37c1d
https://doi.org/10.1159/000501614
https://doi.org/10.1159/000501614
Publikováno v:
International Review of Cell and Molecular Biology ISBN: 9780128240366
In recent decades cancer emerged as one of the leading causes of death in the developed countries, with some types of cancer contributing to the top 10 causes of death on the list of the World Health Organization. Carcinogenesis, a malignant transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5188a80f63c593e0c0d2a2cedea169
https://doi.org/10.1016/bs.ircmb.2021.02.016
https://doi.org/10.1016/bs.ircmb.2021.02.016