Zobrazeno 1 - 10
of 1 970
pro vyhledávání: '"SNpc, substantia nigra pars compacta"'
Publikováno v:
Biochemical Pharmacology. 63:21-29
Antioxidant and anti-inflammatory therapy approaches have been in the focus of attention in the treatment of neurodegenerative Parkinson’s and Alzheimer’s diseases where oxidative stress has been implicated. Tea extracts have been previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ea700321646ecf03fdf7857e4e6c3e
https://doi.org/10.1016/s0006-2952(01)00813-9
https://doi.org/10.1016/s0006-2952(01)00813-9
Publikováno v:
Biochemical Pharmacology. Jan2002, Vol. 63 Issue 1, p21. 9p.
Autor:
A. Cota-Coronado, O.R. Hernández-Pérez, Néstor F. Díaz, Pavel H. Lugo-Fabres, N. Emmanuel Díaz-Martínez, Valeria Valadez-Barba, Eduardo Padilla-Camberos
Publikováno v:
Regenerative Therapy, Vol 15, Iss, Pp 332-339 (2020)
Regenerative Therapy
Regenerative Therapy
Neurodegenerative disorders such as Parkinson's and Alzheimer's disease, are fundamental health concerns all around the world. The development of novel treatments and new techniques to address these disorders, are being actively studied by researcher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533df458e5d5b5603371b246a30631c
http://www.sciencedirect.com/science/article/pii/S2352320420300894
http://www.sciencedirect.com/science/article/pii/S2352320420300894
Autor:
Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya
Publikováno v:
The Journal of Biological Chemistry
Synucleins, a family of three proteins highly expressed in neurons, are predominantly known for the direct involvement of α-synuclein in the etiology and pathogenesis of Parkinson's and certain other neurodegenerative diseases, but their precise phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c25bdcdb04d42ed3e6e25fe31cef99
http://europepmc.org/articles/PMC8633583
http://europepmc.org/articles/PMC8633583
Publikováno v:
IBRO Reports
IBRO Reports, Vol 3, Iss C, Pp 1-8 (2017)
IBRO Reports, Vol 3, Iss C, Pp 1-8 (2017)
Parkinson's disease (PD), a progressive neurodegeneration, is characterized by loss of dopaminergic neurons in the substantia nigra (SN) and loss of motor co-ordination. Impaired metabolism of major lipids such as phospholipids which play regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bff7286cc0964453a641f79e008bc0e
https://doi.org/10.1016/j.ibror.2017.06.001
https://doi.org/10.1016/j.ibror.2017.06.001
Autor:
Connor-Robson, N, Booth, H, Martin, JG, Gao, B, Li, K, Doig, N, Vowles, J, Browne, C, Klinger, L, Juhasz, P, Klein, C, Cowley, SA, Bolam, P, Hirst, W, Wade-Martins, R
Publikováno v:
Neurobiology of Disease, Vol 127, Iss, Pp 512-526 (2019)
Neurobiology of Disease
Neurobiology of Disease
Background Mutations in LRRK2 are the most common cause of autosomal dominant Parkinson's disease, and the relevance of LRRK2 to the sporadic form of the disease is becoming ever more apparent. It is therefore essential that studies are conducted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b7268c281d6c7f4627e2a8bb7ba71182
https://orca.cardiff.ac.uk/id/eprint/142163/1/1-s2.0-S0969996119300968-main.pdf
https://orca.cardiff.ac.uk/id/eprint/142163/1/1-s2.0-S0969996119300968-main.pdf
Publikováno v:
Redox Biology, Vol 22, Iss, Pp-(2019)
Redox Biology
Redox Biology
The activation of NADPH oxidase contributes to dopaminergic neurodegeneration and motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is involved in non-motor symptoms, especially cognitive dysfunction in PD remains unknown. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0d2a312a701be8ce2761d13e178115
http://www.sciencedirect.com/science/article/pii/S2213231719300291
http://www.sciencedirect.com/science/article/pii/S2213231719300291
Autor:
Paul C. Keane, Christopher Morris, P.J. Kahle, Peter S. Hanson, Fiona E. N. LeBeau, Ahmad Khundakar, Peter G. Blain, Sarah J. Judge, Philippa D. Hepplewhite, Lina Patterson
Publikováno v:
Neuroscience letters 711, 134437 (2019). doi:10.1016/j.neulet.2019.134437
Neuroscience Letters
Neuroscience Letters
Highlights • Parkinson’s disease (PD) may have an environmental component involving toxin exposure. • Trichloroethylene (TCE) is a major environmental contaminant and can convert to the toxin TaClo. • We administered TCE and TaClo to wild typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c72fc6dc3fd8505e5e8d6afd86da507
Autor:
Ishikuro, Koji1 (AUTHOR), Hattori, Noriaki1 (AUTHOR), Imanishi, Rieko1 (AUTHOR), Furuya, Kohta1 (AUTHOR), Nakata, Takeshi1 (AUTHOR), Dougu, Nobuhiro2 (AUTHOR), Yamamoto, Mamoru2 (AUTHOR), Konishi, Hirofumi2 (AUTHOR), Nukui, Takamasa2 (AUTHOR), Hayashi, Tomohiro2 (AUTHOR), Anada, Ryoko2 (AUTHOR), Matsuda, Noriyuki2 (AUTHOR), Hirosawa, Hiroaki2 (AUTHOR), Tanaka, Ryo2 (AUTHOR), Shibata, Takashi3 (AUTHOR), Mori, Koichi4 (AUTHOR), Noguchi, Kyo4 (AUTHOR), Kuroda, Satoshi3 (AUTHOR), Nakatsuji, Yuji2 (AUTHOR), Nishijo, Hisao5 (AUTHOR) nishijo@med.u-toyama.ac.jp
Publikováno v:
Neurocase (Taylor & Francis Ltd). Oct 2021, Vol. 27 Issue 5, p407-414. 8p.
Autor:
Mustafa, S., Martin, H.L., Burkly, L., Costa, A., Martins, M.L., Schwaninger, M., Teismann, P.
Publikováno v:
Neuroscience
Highlights • We investigate the role of TWEAK and Fn14 in a model of Parkinson’s disease. • Ablation of TWEAK or Fn14 had no effect on acute MPTP toxicity. • TWEAK neutralizing antibody provided neuroprotection in the sub-acute MPTP-model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::43b6b48a99bee3fa0ef357e7585e1343