Zobrazeno 1 - 10
of 82
pro vyhledávání: '"SNP-based heritability"'
Publikováno v:
Acta Veterinaria Scandinavica, Vol 64, Iss 1, Pp 1-8 (2022)
Abstract Background Distichiasis is the most frequently recorded eye disorder in the Norwegian Staffordshire bull terrier (SBT). The condition is often mild but can, in severe cases, lead to pain and blindness. The current study's main purpose was to
Externí odkaz:
https://doaj.org/article/a81ab43c0fa44b8ab680698c054ffd3a
Autor:
Elisa Zimmermann, Ottmar Distl
Publikováno v:
Animals, Vol 13, Iss 9, p 1462 (2023)
Before the genomics era, heritability estimates were performed using pedigree data. Data collection for pedigree analysis is time consuming and holds the risk of incorrect or incomplete data. With the availability of SNP-based arrays, heritability ca
Externí odkaz:
https://doaj.org/article/47b9b1911a8c480cbcddccb3f696f2c3
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Heterogeneity in the phenotypic mean and variance across populations is often observed for complex traits. One way to understand heterogeneous phenotypes lies in uncovering heterogeneity in genetic effects. Previous studies on genetic heterogeneity a
Externí odkaz:
https://doaj.org/article/20c29ba522164a74b9ba65c503e258bc
Autor:
Michela Traglia, Lisa A. Croen, Karen L. Jones, Luke S. Heuer, Robert Yolken, Martin Kharrazi, Gerald N. DeLorenze, Paul Ashwood, Judy Van de Water, Lauren A. Weiss
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-17 (2018)
Abstract Background The immune system plays a fundamental role in development during pregnancy and early life. Alterations in circulating maternal and neonatal immune mediators have been associated with pregnancy complications as well as susceptibili
Externí odkaz:
https://doaj.org/article/e3fa174e150547e8a60a4ff370e0185b
Autor:
Shangmin Li, Xingguo Wang, Liang Qu, Taocun Dou, Meng Ma, Manman Shen, Jun Guo, Yuping Hu, KeHua Wang
Publikováno v:
Italian Journal of Animal Science, Vol 17, Iss 2, Pp 294-300 (2018)
Small intestine length is an important physiological index that is effected by nutrient intake and thus plays roles in growth and egg-laying in chickens. Although there are some studies about small intestine length, little information is available re
Externí odkaz:
https://doaj.org/article/d51cd4316ea949849d8dafcd42a5061a
Autor:
Andrew D. Grotzinger, Javier de la Fuente, Florian Privé, Michel G. Nivard, Elliot M. Tucker-Drob
Publikováno v:
Biological psychiatry, 93(1), 29-36. Elsevier USA
Grotzinger, A D, Fuente, J D L, Privé, F, Nivard, M G & Tucker-Drob, E M 2023, ' Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis : A Simple Solution ', Biological psychiatry, vol. 93, no. 1, pp. 29-36 . https://doi.org/10.1016/j.biopsych.2022.05.029
Grotzinger, A D, Fuente, J D L, Privé, F, Nivard, M G & Tucker-Drob, E M 2023, ' Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis : A Simple Solution ', Biological Psychiatry, vol. 93, no. 1, pp. 29-36 . https://doi.org/10.1016/j.biopsych.2022.05.029
Biol Psychiatry
Grotzinger, A D, Fuente, J D L, Privé, F, Nivard, M G & Tucker-Drob, E M 2023, ' Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis : A Simple Solution ', Biological psychiatry, vol. 93, no. 1, pp. 29-36 . https://doi.org/10.1016/j.biopsych.2022.05.029
Grotzinger, A D, Fuente, J D L, Privé, F, Nivard, M G & Tucker-Drob, E M 2023, ' Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis : A Simple Solution ', Biological Psychiatry, vol. 93, no. 1, pp. 29-36 . https://doi.org/10.1016/j.biopsych.2022.05.029
Biol Psychiatry
BACKGROUND: Single nucleotide polymorphism-based heritability is a fundamental quantity in the genetic analysis of complex traits. For case-control phenotypes, for which the continuous distribution of risk in the population is unobserved, observed-sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e57a28eef4e74c2912fd3154a45d15
https://doi.org/10.1016/j.biopsych.2022.05.029
https://doi.org/10.1016/j.biopsych.2022.05.029
Autor:
Elnaz Naderi, Line M.H. Schack, Ceilidh Welsh, Adelene Y.L. Sim, Miguel E. Aguado-Barrera, Tom Dudding, Holly Summersgil, Laura Martínez-Calvo, Enya H.W. Ong, Yasmin Odding, Ana Varela-Pazos, Roel J.H.M. Steenbakkers, Anne P.G. Crijns, Rajesh Jena, Miranda Pring, Joe Dennis, Ramón Lobato-Busto, Jan Alsner, Andy Ness, Christopher Nutting, David J Thomson, Antonio Gómez-Caamaño, Jesper G. Eriksen, Steve J. Thomas, Amy M. Bates, Jens Overgaard, Luis M. Cascallar-Caneda, Fréderic Duprez, Gillian C. Barnett, Leila Dorling, Melvin L.K. Chua, Ana Vega, Catharine M.L. West, Johannes A. Langendijk, Christian Nicolaj Andreassen, Behrooz Z. Alizadeh
Publikováno v:
On the behalf of the Radiogenomics Consortium 2022, ' Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer ', Radiotherapy and Oncology, vol. 176, pp. 138-148 . https://doi.org/10.1016/j.radonc.2022.09.016
Radiotherapy and Oncology, 176, 138-148. ELSEVIER IRELAND LTD
2022, ' Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer ', Radiotherapy and Oncology, vol. 176, pp. 138-148 . https://doi.org/10.1016/j.radonc.2022.09.016
Radiotherapy and Oncology, 176, 138-148. ELSEVIER IRELAND LTD
2022, ' Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer ', Radiotherapy and Oncology, vol. 176, pp. 138-148 . https://doi.org/10.1016/j.radonc.2022.09.016
Background and purpose: We aimed to the genetic components and susceptibility variants associated with acute radiation-induced toxicities (RITs) in patients with head and neck cancer (HNC).Materials and methods: We performed the largest meta-GWAS of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4cfa41ad874e5430d290fa08f8c16b
https://pure.au.dk/portal/da/publications/metagwas-identifies-the-heritability-of-acute-radiationinduced-toxicities-in-head-and-neck-cancer(36138fe1-aec2-4815-9b13-ff37414e15e1).html
https://pure.au.dk/portal/da/publications/metagwas-identifies-the-heritability-of-acute-radiationinduced-toxicities-in-head-and-neck-cancer(36138fe1-aec2-4815-9b13-ff37414e15e1).html
Autor:
Qinghao Yang, Chunhui Chen, Zhaoxia Yu, Liang Zhang, Bi Zhu, Kanyin Feng, Zhifang Ye, Jintao Sheng, Junjiao Feng, Chuansheng Chen, Ying Cai, Anqi Li, Qi Dong, Gui Xue, Jing Liu
Publikováno v:
Human brain mapping, vol 41, iss 12
Human Brain Mapping
Human Brain Mapping
Resting‐state functional connectivity profiles have been increasingly shown to be important endophenotypes that are tightly linked to human cognitive functions and psychiatric diseases, yet the genetic architecture of this multidimensional trait is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb70ce72605d4ae0e30df65495433001
https://doi.org/10.1002/hbm.25018
https://doi.org/10.1002/hbm.25018
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Akademický článek
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