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Akademický článek

Design and mathematical analysis of activating transcriptional amplifiers that enable modular temporal control in synthetic juxtacrine circuits

Autor: Calvin Lam

Publikováno v: Synthetic and Systems Biotechnology, Vol 8, Iss 4, Pp 654-672 (2023)

The ability to control mammalian cells such that they self-organize or enact therapeutic effects as desired has incredible implications. Not only would it further our understanding of native processes such as development and the immune response, but

Externí odkaz: https://doaj.org/article/51fec7f4708149d2a6132cee062ce292

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Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma

Autor: Jaehoon Shin, Matthew F. L. Parker, Iowis Zhu, Aryn Alanizi, Carlos I. Rodriguez, Raymond Liu, Payal B. Watchmaker, Mausam Kalita, Joseph Blecha, Justin Luu, Brian Wright, Suzanne E. Lapi, Robert R. Flavell, Hideho Okada, Thea D. Tlsty, Kole T. Roybal, David M. Wilson

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 64, iss 1

For the past several decades, chimeric antigen receptor T cell (CAR T) therapies have shown promise in the treatment of cancers. These treatments would greatly benefit from companion imaging biomarkers to follow the trafficking of T cells in vivo. Us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e364c992d32156f510ca36ba5715a
https://doi.org/10.2967/jnumed.122.264284

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