Zobrazeno 1 - 10
of 2 676
pro vyhledávání: '"SNARE complex"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 5, Pp 653-657 (2024)
Depression is a common cause of human disability and death. Some patients are not sensitive to antidepressants, and also the recurrence rate is very high. Unfortunately, there are many problems with existing antidepressants. So, it is urgent to find
Externí odkaz:
https://doaj.org/article/bd4a7c4f3a114235a7a5a8d837d5506a
Publikováno v:
eLife, Vol 12 (2024)
The SNARE proteins are central in membrane fusion and, at the synapse, neurotransmitter release. However, their involvement in the dual regulation of the synchronous release while maintaining a pool of readily releasable vesicles remains unclear. Usi
Externí odkaz:
https://doaj.org/article/a7423aeb6b7a41ea8293d52ddaa15933
Autor:
Xianping Wang, Jihong Gong, Le Zhu, Huidan Chen, Ziqi Jin, Xiaoqiang Mo, Shen Wang, Xiaofei Yang, Cong Ma
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Neurotransmitter release depends on the fusion of synaptic vesicles with the presynaptic membrane and is mainly mediated by SNARE complex assembly. During the transition of Munc18-1/Syntaxin-1 to the SNARE complex, the opening of
Externí odkaz:
https://doaj.org/article/e3818499f5ad4871b471f3bafec2dd97
Autor:
Daniela Felício, Andreia Dias, Sandra Martins, Estefânia Carvalho, Alexandra M. Lopes, Nádia Pinto, Carolina Lemos, Mariana Santos, Miguel Alves-Ferreira
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Migraine is a common and complex neurological disease potentially caused by a polygenic interaction of multiple gene variants. Many genes associated with migraine are involved in pathways controlling the synaptic function and neurotransmitte
Externí odkaz:
https://doaj.org/article/99d01bb37c1441798b159c5e6deff1eb
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionThe protein fasciculation and elongation zeta-1 (FEZ1) is involved in axon outgrowth but potentially interacts with various proteins with roles ranging from intracellular transport to transcription regulation. Gene association and other s
Externí odkaz:
https://doaj.org/article/49c2138a68d1493ca4083ce833a14667
Publikováno v:
FEBS Open Bio, Vol 12, Iss 11, Pp 1939-1957 (2022)
Neurotransmitter release by Ca2+‐triggered synaptic vesicle exocytosis is essential for information transmission in the nervous system. The soluble N‐ethylmaleimide sensitive factor attachment protein receptors (SNAREs) syntaxin‐1, SNAP‐25, a
Externí odkaz:
https://doaj.org/article/45173847d7364dab860641f5bb6dc3cf
Autor:
Dimitrios Kioumourtzoglou, Hannah L. Black, Mohammed Al Tobi, Rachel Livingstone, John R. Petrie, James G. Boyle, Gwyn W. Gould, Nia J. Bryant
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1738 (2023)
A major consequence of insulin binding its receptor on fat and muscle cells is the stimulation of glucose transport into these tissues. This is achieved through an increase in the exocytic trafficking rate of the facilitative glucose transporter GLUT
Externí odkaz:
https://doaj.org/article/2e125bcbadc74a7d9cf821179cd96c07
Publikováno v:
Nutrients, Vol 16, Iss 1, p 99 (2023)
Vascular calcification (VC) is a pathological condition frequently observed in cardiovascular diseases. Primary factors contributing to VC are osteogenic differentiation of vascular smooth muscle and hydroxyapatite deposition. Targeted autophagy (a l
Externí odkaz:
https://doaj.org/article/a29137aab08e406da5f869f2cdf84e12
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