Výsledky vyhledávání - "SNARE, SNAP receptor"

Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases

Autor: Nadine, Zimmann, Petr, Rada, Vojtěch, Žárský, Tamara, Smutná, Kristína, Záhonová, Joel, Dacks, Karel, Harant, Ivan, Hrdý, Jan, Tachezy

Publikováno v: Molecular & Cellular Proteomics : MCP

The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in parasitic protists. Whereas the mannose 6-phosphate (M6P)-dependent system is dominant for lysoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8b7a8dffd0ed0f52289b27ed2884830
https://pubmed.ncbi.nlm.nih.gov/34763061

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The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF

Autor: Ugo Mayor, Imanol Martínez-Padrón, Juanma Ramirez, Miguel Morales, Nerea Osinalde, Alberto Ferrús

Publikováno v: Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
The Journal of Biological Chemistry
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC

Ariadne-1 (Ari-1) is an E3 ubiquitin-ligase essential for neuronal development, but whose neuronal substrates are yet to be identified. To search for putative Ari-1 substrates, we used an in vivo ubiquitin biotinylation strategy coupled to quantitati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75375988a0ecd8a0071aa6eab5d124cd
http://hdl.handle.net/10261/260697

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Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Autor: Elsa M. Rodarte, Joo-Heon Yoon, Rustam Bagirzadeh, Zoulikha Azzegagh, Rupesh Nigam, James A. McNew, Binhui Ren, Brenton L. Scott, Youlia Petrova, Kyubo Kim, Michael J. Tuvim, Lucia Piccotti, Anurag Agrawal, Alejandra Gomez, Roberto Adachi, Christopher M. Evans, Burton F. Dickey, Vesa M. Olkkonen

Publikováno v: Biochemical Journal

Airway mucin secretion and MC (mast cell) degranulation must be tightly controlled for homoeostasis of the lungs and immune system respectively. We found the exocytic protein Munc18b to be highly expressed in mouse airway epithelial cells and MCs, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a16dcc44d03feca71748d207a23da21
https://doi.org/10.1042/bj20120057

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