Zobrazeno 1 - 10
of 12
pro vyhledávání: '"SNAI1 Gene"'
Background: Diabetic kidney disease is a leading cause of end-stage kidney disease worldwide, its incidence is still increasing and the precise mechanism is not yet fully understood.This study aimed to investigate the possible association of miR-30a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ef3c5e8bd15901ccad155e67ab8fde
https://doi.org/10.21203/rs.3.rs-127615/v1
https://doi.org/10.21203/rs.3.rs-127615/v1
Autor:
Claudio Mussolino, Aleksandra Ulman, Toni Cathomen, Marcin Majka, Klaudia Skrzypek, Paweł Konieczny
Publikováno v:
Cells
Volume 9
Issue 5
Cells, Vol 9, Iss 1095, p 1095 (2020)
Volume 9
Issue 5
Cells, Vol 9, Iss 1095, p 1095 (2020)
Genome editing (GE) tools and RNA interference technology enable the modulation of gene expression in cancer research. While GE mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 or transcription activator-like effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c35beff292408c7a903042b642f4d9
Autor:
Matthew Taras Stecy, Raghu S. Nagalingam, Rushita A. Bagchi, Michael P. Czubryt, Danah S. Al-Hattab, Hamza A. Safi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 315:H658-H668
Numerous physiological and pathological events, from organ development to cancer and fibrosis, are characterized by an epithelial-to-mesenchymal transition (EMT), whereby adherent epithelial cells convert to migratory mesenchymal cells. During cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031aaa128957a7c9c203b7c366b2b085
https://doi.org/10.1152/ajpheart.00092.2018
https://doi.org/10.1152/ajpheart.00092.2018
Autor:
Oscar Nnoli, Jessica A. Warns, Kris Zarns, Bradley Jokinen, Sergei Nechaev, Ata Abbas, Ann Samarakkody, Adam Scheidegger, Brooke Kubat, Archana Dhasarathy
Publikováno v:
Nucleic Acids Research
Promoter-proximal RNA polymerase II (Pol II) pausing is implicated in the regulation of gene transcription. However, the mechanisms of pausing including its dynamics during transcriptional responses remain to be fully understood. We performed global
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f215541aefbd5950da85a135726fa4e2
https://doi.org/10.1093/nar/gkv263
https://doi.org/10.1093/nar/gkv263
Publikováno v:
Development. 134:1789-1797
Palate development requires precise regulation of gene expression changes, morphogenetic movements and alterations in cell physiology. Defects in any of these processes can result in cleft palate, a common human birth defect. The Snail gene family en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8036421c33a424926a1b9f225a4945
https://doi.org/10.1242/dev.02837
https://doi.org/10.1242/dev.02837
Autor:
Stephen A. Murray, Thomas Gridley
Publikováno v:
Cell Cycle. 5:2566-2570
Originally identified as one of two zygotically expressed genes required for gastrulation in Drosophila, the Snail gene and other family members play critical roles in vertebrate development. Functionally, these genes are thought to drive epithelial-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1292d7e1381dc718cda33ecf1765d33
https://doi.org/10.4161/cc.5.22.3502
https://doi.org/10.4161/cc.5.22.3502
Publikováno v:
genesis. 44:7-11
Members of the Snail gene superfamily, which encode zinc finger transcriptional repressors, play critical roles in the establishment of the vertebrate body plan. The Snail1 (Snai1) gene promotes epithelial–mesenchymal transitions during development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ece8f726ef63dccea767d1517c7f58
https://doi.org/10.1002/gene.20178
https://doi.org/10.1002/gene.20178
Autor:
Zeti Karim, Nor Azlin Safina Abdul Aziz, Siti Hamimah Sheikh Abdul Kadir, Umi Marshida Abdul Hamid, Maslinda Musa, Khalilah Abdul Khalil, Farida Zuraina Mohd Yusof
Publikováno v:
Gastroenterology. 150:S371-S372
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffcb7893a6619f426903c8c23beb83d
https://doi.org/10.1016/s0016-5085(16)31306-3
https://doi.org/10.1016/s0016-5085(16)31306-3
Autor:
Andrew O.M. Wilkie, Stephen R.F. Twigg
Publikováno v:
Human Genetics. 105:320-326
The Snail family of proteins in vertebrates comprises two zinc-finger transcription factors, Snail and Slug, which are thought to be involved in the formation of the mesoderm and neural crest. Here, we describe the isolation and characterisation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de87dc2a40ab3bbcba0b2b7c5bc918e
https://doi.org/10.1007/s004399900143
https://doi.org/10.1007/s004399900143
Autor:
Thomas Gridley, Ying Chen, Luke T. Krebs, Christine R. Norton, Jeong Kyo Yoon, Cara K. Bradley, Xiang Hua Han
Publikováno v:
PLoS Currents
The Snail gene family encodes DNA-binding zinc finger proteins that function as transcriptional repressors. While the Snai1 and Snai2 genes are required for normal development in mice, Snai3 mutant mice exhibit no obvious abnormalities. The Snai3 gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd246657d373b6e2c582e97213e1978
http://europepmc.org/articles/PMC3828230
http://europepmc.org/articles/PMC3828230