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pro vyhledávání: '"SMe1EC2"'
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Akademický článek
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Publikováno v:
Interdisciplinary Toxicology, Vol 10, Iss 4, Pp 148-154 (2017)
Interdisciplinary Toxicology
Interdisciplinary Toxicology
The pentose phosphate pathway and glutathione-associated metabolism are the main antioxidant cellular defense systems. This study investigated the effects of the powerful antioxidant SMe1EC2 (2-ethoxycarbonyl-8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyri
Autor:
Stankovicová T, Zuzana Brnoliakova, Štefan Bezek, Viktor Bauer, Vladimir Knezl, Ružena Sotníková
Publikováno v:
Interdisciplinary Toxicology, Vol 10, Iss 3, Pp 86-92 (2017)
Interdisciplinary Toxicology
Interdisciplinary Toxicology
Metabolic syndrome belongs to the most important risk factors of cardiovascular diseases. The aim of this study was to investigate changes in cardiovascular system induced by high cholesterol and high fat diet (HCHF) in HTG rats and their influence b
Autor:
Ružena Sotníková, Zuzana Brnoliakova, Ema Paulovičová, Štefan Bezek, Jana Navarová, Viktor Bauer, Vladimir Knezl
Publikováno v:
Interdisciplinary Toxicology, Vol 10, Iss 3, Pp 81-85 (2017)
Interdisciplinary Toxicology
Interdisciplinary Toxicology
Elevated plasma cholesterol, especially low density lipoprotein (LDL) cholesterol, is one of the major risk factors for atherosclerosis and coronary heart disease. Hereditary hypertriglyceridemic rats (hHTG) were developed as a new inbred model for t
Autor:
Grzegorz Bartosz, Łukasz Pułaski, Joanna Drzewinska, Łukasz Piotrowski, Milan Stefek, Aneta Balcerczyk
Publikováno v:
Interdisciplinary Toxicology, Vol 7, Iss 1, Pp 27-32 (2014)
Interdisciplinary Toxicology
Interdisciplinary Toxicology
The aim of the study was to evaluate the antioxidant action of SMe1EC2, the structural analogue of the hexahydropyridoindole antioxidant stobadine. The antiradical activity of SMe1EC2 was found to be higher when compared to stobadine, as determined b
Autor:
Ulusu, Nuriye Nuray (ORCID 0000-0002-3173-1389 & YÖK ID 6807), Gök, Müslüm, Sayın Şakul, Arzu Ayşe, Arı, Nuray, Stefek, Milan, Karasu, Çimen, School of Medicine, Department of Medical Biochemistry
Publikováno v:
Interdisciplinary Toxicology
The pentose phosphate pathway and glutathione-associated metabolism are the main antioxidant cellular defense systems. This study investigated the effects of the powerful antioxidant SMe1EC2 (2-ethoxycarbonyl-8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3076::08b230f4a0147d76d8a3b10dce3f4342
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/4480
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/4480
Publikováno v:
Interdisciplinary Toxicology
The antioxidant and reactive-oxygen-species-scavenging activity of stobadine has been demonstrated in previous studies. Recently, chemical modification of this leading structure led to the synthesis of other pyridoindole derivatives with significantl
Autor:
Vladimir Knezl, Zuzana Broskova, Ružena Sotníková, Viktor Bauer, Katarína Drábiková, Katalin Szöcs, Štefan Bezek, Jana Navarová, Zuzana Kyseľová, V Kristová, Peter Křenek, Ján Dřímal, Jana Nedelcevova, Iveta Bernatova, Ľudmila Okruhlicová, Viera Nosáľová
Publikováno v:
Interdisciplinary Toxicology
Protection of the vascular endothelium in experimental situationsOne of the factors proposed as mediators of vascular dysfunction observed in diabetes is the increased generation of reactive oxygen species (ROS). This provides support for the use of
Autor:
Ružena Sotníková, Silvia Banášová, Katarína Drábiková, Jana Navarová, Silvia Fialová, Viera Nosáľová, Daniela Košťálová
Publikováno v:
Interdisciplinary Toxicology
Chemiluminescence response induced by mesenteric ischaemia/reperfusion: effect of antioxidative compoundsex vivoIschaemia and reperfusion (I/R) play an important role in human pathophysiology as they occur in many clinical conditions and are associat