Zobrazeno 1 - 10
of 2 600
pro vyhledávání: '"SMO, smoothened"'
Publikováno v:
Journal of IMAB, Vol 26, Iss 2, Pp 3102-3106 (2020)
Basal Cell Carcinoma (BCC) is one of the well spread malignant skin cancers. Eighty percent of it occurs in the head-neck area of which 20% in the eyelids. The major genes for BCC are: PTCH1 and PTCH2. PTCH1 supresses transmembrane Smoothened (SMO) p
Externí odkaz:
https://doaj.org/article/675a5127251a4b778d9b65aa6173960d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Pancreas. 33(1)
OBJECTIVES To investigate the prevalence of PTCH (patched gene) and Smo (smoothened gene) expression in human pancreatic cancerous tissues and its association with clinical characteristics. METHODS A rabbit polyclonal antibody against PTCH was prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31653b06d15eda1c92127a8b92558937
https://pubmed.ncbi.nlm.nih.gov/16804411
https://pubmed.ncbi.nlm.nih.gov/16804411
Publikováno v:
Pancreas; July 2006, Vol. 33 Issue: 1 p38-44, 7p
Autor:
Xian Zeng, Dianwen Ju, Jiajun Fan, Yichen Wang, Jinghui Zhang, Jingyun Luan, Kai Yin, Mingming Nie
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9591fe5f71a6d93ff75c586983adcb
https://doi.org/10.1016/j.apsb.2020.10.022
https://doi.org/10.1016/j.apsb.2020.10.022
Autor:
Wenfu Tan, Huaqian Ding, Xiaohua Liu, Chunyong Ding, Juan Wang, Yalei Li, Ao Zhang, Yu Zhang, Hongchun Liu, Wenjing Huang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 488-504 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Medulloblastoma (MB) is a common yet highly heterogeneous childhood malignant brain tumor, however, clinically effective molecular targeted therapy is lacking. Modulation of hedgehog (HH) signaling by epigenetically targeting the transcriptional fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301cde2b3eb755a22e93dd5c8eb925b1
https://doi.org/10.1016/j.apsb.2020.07.007
https://doi.org/10.1016/j.apsb.2020.07.007
Autor:
Kaidonis, Georgia, Pekmezci, Melike, Van Ziffle, Jessica, Auguste, Kurtis I, Horton, Jonathan C
Publikováno v:
Journal of neurosurgery. Case lessons, vol 3, iss 23
BACKGROUND In the past decade, next-generation sequencing has spurred significant progress in the understanding of cytogenetic alterations that occur in meningiomas. Eighty percent of adult meningiomas harbor pathogenic somatic variants involving NF2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f43346690f3db1716396b938997aca
https://doi.org/10.3171/case2247
https://doi.org/10.3171/case2247
Autor:
Sai Yao, Fangda Fu, Peijian Tong, Hongting Jin, Taotao Xu, Hongfeng Ruan, Chengliang Wu, Huan Yu, Di Chen, Huan Luo
Publikováno v:
Journal of Orthopaedic Translation, Vol 24, Iss, Pp 103-111 (2020)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Summary Purpose The purpose of our study was to introduce and validate a metal-free, reproducible and reliable mouse model of anterior cruciate ligament (ACL) reconstruction (ACLR) surgery as an effective tool for a better understanding of molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be33b81f4d48c4bf41250e4fcc3ac8d
http://www.sciencedirect.com/science/article/pii/S2214031X2030070X
http://www.sciencedirect.com/science/article/pii/S2214031X2030070X
Autor:
Shan, Gang1, Li, Houhua1, Ziegler, Slava1, Flegel, Jana1,2, Antonchick, Andrey P.1,2, Waldmann, Herbert1,2, Merten, Christian3
Publikováno v:
Angewandte Chemie. 10/22/2018, Vol. 130 Issue 43, p14446-14450. 5p.