Zobrazeno 1 - 10
of 218
pro vyhledávání: '"SMITH, E. W."'
Autor:
Smith, E W, Haigh, J M
The human skin blanching (vasoconstriction) assay has been in use for 3 decades as a tool for the assessment of the release of corticosteroids from topical dosage forms. Application of corticosteroids produces a whitening (blanching) of the skin, the
Externí odkaz:
http://hdl.handle.net/10962/d1006609
In a recent Guidance document the American FDA recommended the use of a chromameterrather thanthe human eye for the assessment of the pharmacodynamic blanching response produced after topical application of corticosteroids. The purpose of this study
Externí odkaz:
http://hdl.handle.net/10962/d1006611
Bioavailability concerns for topical dermatological products are complex and it is especially difficult to determine the bioequivalence of similar topical formulations. Since only small amounts of drug dispersed in an appropriate vehicle are applied
Externí odkaz:
http://hdl.handle.net/10962/d1006608
A major problem encountered in the transdermal delivery of drugs is the effectiveness of the barrier system imposed by the stratum corneum.To overcome tbe resistance of the skin to the ingress of exogenous chemicals, numerous innovative techniques re
Externí odkaz:
http://hdl.handle.net/10962/d1006537
Chromameters are compact portable instruments used for the assessment of surface colour based on the tristimulus analysis of a reflected xenon light pulse, and have been used for the quantification of erythema in the study of irritant dermatitis, and
Externí odkaz:
http://hdl.handle.net/10962/d1006610
Autor:
Smith, E W, Haigh, J M
From introduction: Topical corticosteroids have been used for a wide range of dermatological conditions for the last 4 decades. For many years the topical delivery system was a relatively simple cream or ointment base, with little thought given to im
Externí odkaz:
http://hdl.handle.net/10962/d1006629
Autor:
Smith, E W, Haigh, J M
From introduction: Topical corticosteroids are still the most widely used drugs in the treatment of dermatological conditions. Early corticosteroid dosage forms consisted of simple creams or ointments where more emphasis was placed on the potency of
Externí odkaz:
http://hdl.handle.net/10962/d1006624
Consumers of topical formulations apply a wide spectrum of preparations, both cosmetic and dermatological, to their healthy or diseased skin. These formulations range in physicochemical nature from solid through semisolid to liquid. Pharmaceutical fo
Externí odkaz:
http://hdl.handle.net/10962/d1006541