Zobrazeno 1 - 10
of 130
pro vyhledávání: '"SMAD1/5/8"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundAstrocytic activation in the spinal dorsal horn contributes to the central sensitization of neuropathic pain. Bone morphogenetic protein (BMP) 10, one of the BMPs highly expressed in the central nervous system, has been demonstrated to have
Externí odkaz:
https://doaj.org/article/c309d7a65b0649ab9289da3f58847cfe
Autor:
Patrick Andre, Sachindra R. Joshi, Steven D. Briscoe, Mark J. Alexander, Gang Li, Ravindra Kumar
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Pulmonary arterial hypertension (PAH) is a rare disease characterized by high blood pressure in the pulmonary circulation driven by pathological remodeling of distal pulmonary arteries, leading typically to death by right ventricular failure. Availab
Externí odkaz:
https://doaj.org/article/f8699ba963934b06b821ed7462350abe
Akademický článek
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Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-13 (2019)
Abstract Background There are two isoforms of sphingomyelin synthase (SMS): SMS1 and SMS2. SMS1 is located in the Golgi apparatus only while SMS2 is located in both the plasma membrane and the Golgi apparatus. SMS1 and SMS2 act similarly to generate
Externí odkaz:
https://doaj.org/article/b894456745fd4dfb91d40a8854be0958
Akademický článek
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Akademický článek
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Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1590 (2021)
Hepcidin, a major regulator of systemic iron homeostasis, is mainly induced in hepatocytes by activating bone morphogenetic protein 6 (BMP-6) signaling in response to changes in the iron status. Small heterodimer partner-interacting leucine zipper pr
Externí odkaz:
https://doaj.org/article/1b2ac22c1242433480d83c5b1d58f01e
Autor:
Xin Jin, Er Nie, Xu Zhou, Ailiang Zeng, Tianfu Yu, Tongle Zhi, Kuan Jiang, Yingyi Wang, Junxia Zhang, Yongping You
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1616-1628 (2017)
Background: Gliomas result in the highest morbidity and mortality rates of intracranial primary central nervous system tumors because of their aggressive growth characteristics and high postoperative recurrence. They are characterized by genetic inst
Externí odkaz:
https://doaj.org/article/f903ae12986f422b95f59fb2c2afeecb
CTGF Positively Regulates BMP12 Induced Tenogenic Differentiation of Tendon Stem Cells and Signaling
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 1831-1845 (2015)
Background/Aims: Disordered differentiation of tendon stem cells (TSCs) during repair of injured tendon can result in the pathogenesis of chronic tendinopathy. Understanding tenocyte differentiation may provide new therapeutic insights for the preven
Externí odkaz:
https://doaj.org/article/c8204b2f5c8c4db1aae62bf857ae7d94
Autor:
Long-jiao Wang, Guo-ping Zhao, Xi-fan Wang, Xiao-xue Liu, Yi-xuan Li, Li-li Qiu, Xiao-yu Wang, Fa-zheng Ren
Publikováno v:
Nutrients; Volume 14; Issue 15; Pages: 3176
Increasing hepcidin expression is a vital factor in iron homeostasis imbalance among patients with chronic kidney disease (CKD). Recent studies have elucidated that abnormal serum steroid levels might cause the elevation of hepcidin. Glycochenodeoxyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a28d282a5cb60fddd9203b41d5b7c54
https://pubmed.ncbi.nlm.nih.gov/35956351
https://pubmed.ncbi.nlm.nih.gov/35956351