Výsledky vyhledávání - "SMAD, SMA/MAD homologous"

Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling

Autor: J.L. Robertus, Aida M. Bertoli-Avella, S.E. Hoeks, R.M.G.B. Buijs-Offerman, P.M. van Heijningen, Jeroen Essers, B.S. van Thiel, M. Vermeij, Roland Kanaar, Hence J.M. Verhagen, Yanto Ridwan, J.H. von der Thusen, N. van Vliet, I. van der Pluijm

Publikováno v: EBioMedicine
EBioMedicine, 12, 280-294. Elsevier
EBioMedicine, Vol 12, Iss C, Pp 280-294 (2016)

Aneurysm-osteoarthritis syndrome characterized by unpredictable aortic aneurysm formation, is caused by SMAD3 mutations. SMAD3 is part of the SMAD2/3/4 transcription factor, essential for TGF-β-activated transcription. Although TGF-β-related gene m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a03f1e11795c843f014cab1e1e2decf

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