Versatile workflow for cell type resolved transcriptional and epigenetic profiles from cryopreserved human lung

Autor: M Llamazares Prada, E Espinet, V Mijosek, U Schwartz, SM Waszak, P Lutsik, R Tamas, M Richter, A Behrendt, S Pohl, N Benz, T Muley, A Warth, CP Heußel, H Winter, F Herth, T Mertens, H Karmouty-Quintana, I Koch, V Benes, JO Korbel, A Trumpp, D Wyatt, H Stahl, C Plass, RZ Jurkowska

The complexity of the lung microenvironment together with changes in cellular composition during disease progression make it exceptionally hard to understand the molecular mechanisms leading to the development of chronic lung diseases. Although recen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c616c8dbb9416be19e9ac24b0b2f8f9
https://doi.org/10.1101/2020.04.01.018861

Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC.

Autor: Mueller S; Department of Neurology, Neurosurgery and Pediatrics, University of California, San Francisco, California, USA., Kline C; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Franson A; Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., van der Lugt J; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Prados M; Department of Neurosurgery and Pediatrics, University of California, San Francisco, San Francisco, California, USA., Waszak SM; Department of Neurology, University of California, San Francisco, San Francisco, California, USA.; Laboratory of Computational Neuro-Oncology, Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Plasschaert SLA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Molinaro AM; Division of Biomedical Statistics and Informatics, Department of Neurosurgery, University of California, San Francisco, San Francisco, California, USA., Koschmann C; Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., Nazarian J; Research Center for Genetic Medicine, Children's National Health System, Washington, District of Columbia, USA.; Brain Tumor Institute, Children's National Health System, Washington, District of Columbia, USA.; DMG Research Center, Department of Pediatrics, University Children's Hospital, University of Zurich, Zürich, Switzerland.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 May 03; Vol. 26 (Supplement_2), pp. S125-S135.

Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.

Autor: Kolodziejczak AS; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany., Guerrini-Rousseau L; Department of Children and Adolescents Oncology, Gustave Roussy, Université Paris-Saclay, 94805 Villejuif, France.; Molecular Predictors and New Targets in Oncology, Inserm U981 Team 'Genomics and Oncogenesis of pediatric Brain Tumors,' Gustave Roussy, Université Paris-Saclay, Villejuif, France., Planchon JM; Department of Diagnostic and Theranostic Medicine, Somatic Genetics Unit, Institut Curie, Paris-Science Lettres University, Paris, France., Ecker J; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany., Selt F; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany., Mynarek M; Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred Scheel Cancer Career Center HaTriCS4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Obrecht D; Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sill M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Autry RJ; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Stutheit-Zhao E; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Hirsch S; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Amouyal E; SIREDO Pediatric Oncology Center, Institut Curie, Paris-Science Lettres University, Paris, France., Dufour C; Department of Children and Adolescents Oncology, Gustave Roussy, Université Paris-Saclay, 94805 Villejuif, France.; Molecular Predictors and New Targets in Oncology, Inserm U981 Team 'Genomics and Oncogenesis of pediatric Brain Tumors,' Gustave Roussy, Université Paris-Saclay, Villejuif, France., Ayrault O; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Torrejon J; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Waszak SM; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Neurology, University of California, San Francisco, CA, USA., Ramaswamy V; Division of Neurosurgery, Program in Developmental and Stem Cell Biology, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario, Canada., Pentikainen V; Division of Hematology-Oncology and Stem Cell Transplantation, Children's Hospital, Helsinki University Hospital, Helsinki, Finland., Demir HA; Department of Pediatric Hematology-Oncology, Private Memorial Ankara Hospital, Ankara, Turkey., Clifford SC; Wolfson Childhood Cancer Research Centre, Newcastle University Centre for Cancer, Newcastle upon Tyne, United Kingdom., Schwalbe EC; Wolfson Childhood Cancer Research Centre, Newcastle University Centre for Cancer, Newcastle upon Tyne, United Kingdom.; Applied Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom., Massimi L; Pediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University Medical School, Rome, Italy., Snuderl M; Department of Pathology, New York University Langone Health, New York City, NY, USA., Galbraith K; Department of Pathology, New York University Langone Health, New York City, NY, USA., Karajannis MA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Hill K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Li BK; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Walsh M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., White CL; Victorian Clinical Genetics Services, Parkville, Australia.; Hudson Institute of Medical Research, Clayton, Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Australia., Redmond S; Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland., Loizos L; Pediatric Oncology/Hematology/Immunology at the Medical School of the University of Nicosia, Nicosia, Cyprus., Jakob M; Department of Paediatric Haematology, Oncology and Stem-Cell Transplantation, University Hospital Regensburg, Regensburg, Germany., Kordes UR; Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schmid I; Paediatric Haematology and Oncology, Dr. von Hauner Children's Hospital, Ludwig Maximilians University Munich, Munich, Germany., Hauer J; Pediatric Haematology and Oncology, University Hospital Carl Gustav Carus, Dresden, Germany., Blattmann C; Paediatric Haematology, Oncology and Immunology, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany., Filippidou M; Division of Pediatric Hematology-Oncology, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece., Piccolo G; Neuro-Oncology Unit, IRCCS Istituto Giannina Gaslini, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Scheurlen W; Paediatric Haematology and Oncology, Cnopfsche Paediatric Clinic, Nurnberg, Germany., Farrag A; Department of Paediatric Haematology, Oncology and Stem-Cell Transplantation, Paediatric Clinic, University Hospital Aachen, Aachen, Germany.; Department of Pediatric Oncology, South Egypt Cancer Institute, Assiut University, Egypt., Grund K; Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Sutter C; Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Pietsch T; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Frank S; Division of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland., Schewe DM; Department of Pediatrics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany., Malkin D; Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ben-Arush M; Pediatric Hematology Oncology, Rambam Medical Center, Haifa, Israel., Sehested A; Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Copenhagen University Hospital, Copenhagen, Denmark., Wong TT; Division of Pediatric Neurosurgery, Department of Neurosurgery, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan., Wu KS; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Liu YL; Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Carceller F; Paediatric and Adolescent Oncology Drug Development Team, Children and Young People's Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, United Kingdom., Mueller S; Department of Neurology, Neurosurgery and Pediatrics, University of California, San Francisco, USA., Stoller S; Department of Neurology, University of California, San Francisco, USA., Taylor MD; Division of Neurosurgery, Program in Developmental and Stem Cell Biology, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada., Tabori U; Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario, Canada., Bouffet E; Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Division of Haematology/ Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada., Kool M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands., Sahm F; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, and CCU Neuropathology, German Cancer Institute (DKF), Heidelberg, Germany., von Deimling A; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, and CCU Neuropathology, German Cancer Institute (DKF), Heidelberg, Germany., Korshunov A; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, and CCU Neuropathology, German Cancer Institute (DKF), Heidelberg, Germany., von Hoff K; Department of Pediatric Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark., Kratz CP; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Sturm D; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany.; Pediatric Glioma Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Jones DTW; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Glioma Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Rutkowski S; Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., van Tilburg CM; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany., Witt O; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany., Bougeard G; Univ Rouen Normandie, Inserm U1245 and CHU Rouen, Department of Genetics, F-76000 Rouen, France., Pajtler KW; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Pfister SM; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Bourdeaut F; SIREDO Pediatric Oncology Center, Institut Curie, Paris-Science Lettres University, Paris, France., Milde T; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; CCU Pediatric Oncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Hospital, Heidelberg, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2023 Dec 08; Vol. 25 (12), pp. 2273-2286.

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.

Autor: Venneti S; University of Michigan, Ann Arbor, Michigan., Kawakibi AR; University of Michigan, Ann Arbor, Michigan., Ji S; University of Michigan, Ann Arbor, Michigan., Waszak SM; University of California, San Francisco, San Francisco, California.; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.; Laboratory of Computational Neuro-Oncology, Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Sweha SR; University of Michigan, Ann Arbor, Michigan.; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., Mota M; University of Michigan, Ann Arbor, Michigan., Pun M; University of Michigan, Ann Arbor, Michigan., Deogharkar A; University of Michigan, Ann Arbor, Michigan., Chung C; University of Michigan, Ann Arbor, Michigan.; Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Tarapore RS; Chimerix, Inc., Durham, North Carolina., Ramage S; Chimerix, Inc., Durham, North Carolina., Chi A; NYU Langone Health, New York, New York., Wen PY; Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts., Arrillaga-Romany I; Massachusetts General Hospital, Boston, Massachusetts., Batchelor TT; Brigham and Women's Hospital, Boston, Massachusetts., Butowski NA; University of California, San Francisco, San Francisco, California., Sumrall A; Levine Cancer Institute, Charlotte, North Carolina., Shonka N; Mayo Clinic, Rochester, Minnesota., Harrison RA; BC Cancer, The University of British Columbia, Vancouver, BC, Canada., de Groot J; University of California, San Francisco, San Francisco, California., Mehta M; Miami Cancer Institute, Miami, Florida., Hall MD; Miami Cancer Institute, Miami, Florida., Daghistani D; Miami Cancer Institute, Miami, Florida., Cloughesy TF; University of California, Los Angeles, Los Angeles, California., Ellingson BM; University of California, Los Angeles, Los Angeles, California., Beccaria K; Department of Neurosurgery, Necker Sick Children's University Hospital and Paris Descartes University, Paris, France., Varlet P; Department of Neuropathology, Sainte-Anne Hospital and Paris Descartes University, Paris, France., Kim MM; University of Michigan, Ann Arbor, Michigan., Umemura Y; University of Michigan, Ann Arbor, Michigan., Garton H; University of Michigan, Ann Arbor, Michigan., Franson A; University of Michigan, Ann Arbor, Michigan., Schwartz J; Mayo Clinic, Rochester, Minnesota., Jain R; NYU Langone Health, New York, New York., Kachman M; University of Michigan, Ann Arbor, Michigan., Baum H; University of Michigan, Ann Arbor, Michigan., Burant CF; University of Michigan, Ann Arbor, Michigan., Mottl SL; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway., Cartaxo RT; University of Michigan, Ann Arbor, Michigan., John V; University of Michigan, Ann Arbor, Michigan., Messinger D; University of Michigan, Ann Arbor, Michigan., Qin T; University of Michigan, Ann Arbor, Michigan., Peterson E; University of Michigan, Ann Arbor, Michigan., Sajjakulnukit P; University of Michigan, Ann Arbor, Michigan., Ravi K; University of Michigan, Ann Arbor, Michigan., Waugh A; University of Michigan, Ann Arbor, Michigan., Walling D; University of Michigan, Ann Arbor, Michigan., Ding Y; University of Michigan, Ann Arbor, Michigan., Xia Z; University of Michigan, Ann Arbor, Michigan., Schwendeman A; University of Michigan, Ann Arbor, Michigan., Hawes D; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California., Yang F; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California., Judkins AR; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California., Wahl D; University of Michigan, Ann Arbor, Michigan., Lyssiotis CA; University of Michigan, Ann Arbor, Michigan., de la Nava D; Health Research Institute of Navarra (IdiSNA), Pamplona, Spain.; Solid Tumor Program, Cima Universidad de Navarra, Pamplona, Spain.; Department of Pediatrics, Clínica Universidad de Navarra, Pamplona, Spain., Alonso MM; Health Research Institute of Navarra (IdiSNA), Pamplona, Spain.; Solid Tumor Program, Cima Universidad de Navarra, Pamplona, Spain.; Department of Pediatrics, Clínica Universidad de Navarra, Pamplona, Spain., Eze A; Center for Genetic Medicine Research, Children's National Hospital, Washington, DC., Spitzer J; Institute of Innate Immunity, AG Immunogenomics, University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, AG Immunmonitoring and Genomics, University Hospital Bonn, Bonn, Germany., Schmidt SV; Institute of Innate Immunity, AG Immunogenomics, University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, AG Immunmonitoring and Genomics, University Hospital Bonn, Bonn, Germany., Duchatel RJ; Cancer Signalling Research Group, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; Paediatric Program, Mark Hughes Foundation Centre for Brain Cancer Research, College of Health, Medicine, and Wellbeing, Callaghan, NSW, Australia., Dun MD; Cancer Signalling Research Group, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; Paediatric Program, Mark Hughes Foundation Centre for Brain Cancer Research, College of Health, Medicine, and Wellbeing, Callaghan, NSW, Australia., Cain JE; Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Sciences, Monash University, Clayton, VIC, Australia., Jiang L; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Stopka SA; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Baquer G; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Filbin MG; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Agar NYR; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Zhao L; University of Michigan, Ann Arbor, Michigan., Kumar-Sinha C; University of Michigan, Ann Arbor, Michigan., Mody R; University of Michigan, Ann Arbor, Michigan., Chinnaiyan A; University of Michigan, Ann Arbor, Michigan., Kurokawa R; University of Michigan, Ann Arbor, Michigan.; The University of Tokyo, Tokyo, Japan., Pratt D; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Yadav VN; Department of Pediatrics at Children's Mercy Research Institute, Kansas City, Missouri., Grill J; Department of Pediatric and Adolescent Oncology and INSERM Unit 981, Gustave Roussy and University Paris-Saclay, Villejuif, France., Kline C; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Mueller S; University of California, San Francisco, San Francisco, California.; Department of Oncology, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland., Resnick A; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Nazarian J; Department of Pediatrics, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.; Research Center for Genetic Medicine, Children's National Hospital, Washington, DC.; George Washington University School of Medicine and Health Sciences, Washington, DC., Allen JE; Chimerix, Inc., Durham, North Carolina., Odia Y; Miami Cancer Institute, Miami, Florida., Gardner SL; NYU Langone Health, New York, New York., Koschmann C; University of Michigan, Ann Arbor, Michigan.

Publikováno v: Cancer discovery [Cancer Discov] 2023 Nov 01; Vol. 13 (11), pp. 2370-2393.

Enterosignatures define common bacterial guilds in the human gut microbiome.

Autor: Frioux C; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK; Inria, University of Bordeaux, INRAE, 33400 Talence, France. Electronic address: clemence.frioux@inria.fr., Ansorge R; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK., Özkurt E; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK., Ghassemi Nedjad C; Inria, University of Bordeaux, INRAE, 33400 Talence, France., Fritscher J; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK., Quince C; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK., Waszak SM; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo 0318, Norway; Department of Neurology, University of California, San Francisco, San Francisco, CA 94148, USA; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany., Hildebrand F; Food, Microbiome, and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UQ Norwich, Norfolk, UK; Digital Biology, Earlham Institute NR4 7UZ Norwich, Norfolk, UK. Electronic address: falk.hildebrand@quadram.ac.uk.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2023 Jul 12; Vol. 31 (7), pp. 1111-1125.e6. Date of Electronic Publication: 2023 Jun 19.