Zobrazeno 1 - 8 of 8 pro vyhledávání: '"SM Sake"'
3
Akademický článek
Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets.
Autor: Haid S; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Matthaei A; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Winkler M; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Sake SM; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Gunesch AP; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Milke V; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Köhler NM; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Rückert J; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research, Hannover-Braunschweig Site, Hannover, Germany., Vieyres G; Junior Research Group 'Cell Biology of RNA Viruses', Leibniz Institute of Experimental Virology, Hamburg, Germany.; Integrative Analysis of Pathogen-Induced Compartments, Leibniz ScienceCampus InterACt, Hamburg, Germany., Kühl D; Junior Research Group 'Cell Biology of RNA Viruses', Leibniz Institute of Experimental Virology, Hamburg, Germany., Nguyen T-T; Calibr, a Division of The Scripps Research Institute, La Jolla, California, USA., Göhl M; German Center for Infection Research, Hannover-Braunschweig Site, Hannover, Germany.; Helmholtz Centre for Infection Research, Braunschweig, Germany., Lasswitz L; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.; Department of Biochemistry & Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany., Zapatero-Belinchón FJ; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.; Department of Biochemistry & Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany., Brogden G; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.; Department of Biochemistry & Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany., Gerold G; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.; Department of Biochemistry & Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany.; Department of Clinical Microbiology, Virology, 901 87 Umeå University, Umeå, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), 901 87 Umeå University, Umeå, Sweden.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Wiegmann B; Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.; Lower Saxony Center for Biomedical Engineering, Implant Research and Development, Hannover Medical School, Hannover, Germany.; BREATH (Biomedical Research in Endstage and Obstructive Lung Disease Hannover), German Center for Lung Research (DZL), Carl-Neuberg Str. 1, Hannover, Germany., Bilitewski U; Helmholtz Centre for Infection Research, Braunschweig, Germany., Brown RJP; Division of Veterinary Medicine, Paul Ehrlich Institute, Langen, Germany.; Department of Molecular and Medical Virology, Ruhr University, Bochum, Germany., Brönstrup M; German Center for Infection Research, Hannover-Braunschweig Site, Hannover, Germany.; Helmholtz Centre for Infection Research, Braunschweig, Germany., Schulz TF; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research, Hannover-Braunschweig Site, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Pietschmann T; Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.; German Center for Infection Research, Hannover-Braunschweig Site, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.
Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Mar 06; Vol. 68 (3), pp. e0121023. Date of Electronic Publication: 2024 Feb 06.
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4
Akademický článek
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Autor: Sake SM; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Zhang X; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Rajak MK; Institute of Virology, Hannover Medical School, Hannover, Germany.; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany., Urbanek-Quaing M; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Carpentier A; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Gunesch AP; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Grethe C; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Matthaei A; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Rückert J; Institute of Virology, Hannover Medical School, Hannover, Germany., Galloux M; Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France., Larcher T; INRAE Oniris, PAnTher, APEX, Oniris, Nantes, France., Le Goffic R; Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France., Hontonnou F; Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France., Chatterjee AK; Calibr, Scripps Research, La Jolla, CA, USA., Johnson K; Calibr, Scripps Research, La Jolla, CA, USA., Morwood K; Calibr, Scripps Research, La Jolla, CA, USA., Rox K; Department of Chemical Biology, Helmholtz Center of Infection Research, Braunschweig, Germany.; German Centre for Infection Research, Partner site Braunschweig-Hannover, Braunschweig, Germany., Elgaher WAM; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-HZI, Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Huang J; Insitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wetzke M; Department for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.; German Center for Lung Research, Partner Site Hannover, BREATH, Hannover, Germany., Hansen G; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Department for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.; German Center for Lung Research, Partner Site Hannover, BREATH, Hannover, Germany., Fischer N; Insitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Eléouët JF; Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France., Rameix-Welti MA; Université Paris-Saclay, Université de Versailles St. Quentin; UMR 1173 (2I), INSERM; Assistance Publique des Hôpitaux de Paris, Hôpital Ambroise Paré, Laboratoire de Microbiologie, DMU15, Versailles, France., Hirsch AKH; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-HZI, Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Helmholtz International Lab for Anti-infectives, HZI, Braunschweig, Germany., Herold E; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany., Empting M; German Centre for Infection Research, Partner site Braunschweig-Hannover, Braunschweig, Germany.; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-HZI, Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Lauber C; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Schulz TF; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Centre for Infection Research, Partner site Braunschweig-Hannover, Braunschweig, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Krey T; Institute of Virology, Hannover Medical School, Hannover, Germany.; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany.; Centre for Structural Systems Biology (CSSB), Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Luebeck-Borstel-Riems, Luebeck, Germany., Haid S; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany. sibylle.haid@twincore.de., Pietschmann T; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany. thomas.pietschmann@twincore.de.; German Centre for Infection Research, Partner site Braunschweig-Hannover, Braunschweig, Germany. thomas.pietschmann@twincore.de.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany. thomas.pietschmann@twincore.de.; Helmholtz International Lab for Anti-infectives, HZI, Braunschweig, Germany. thomas.pietschmann@twincore.de.
Publikováno v: Nature communications [Nat Commun] 2024 Feb 08; Vol. 15 (1), pp. 1173. Date of Electronic Publication: 2024 Feb 08.
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5
Akademický článek
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages.
Autor: Sake SM; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Kosch C; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany., Blockus S; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Haid S; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Gunesch AP; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Zhang X; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Friesland M; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Trummer SB; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Grethe C; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Kühnel A; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany., Rückert J; Institute of Virology, Hanover Medical Schoolgrid.10423.34, Hanover, Germany.; German Centre for Infection Research, Hanover-Braunschweig Site, Hanover, Germany., Duprex WP; Centre for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Huang J; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorfgrid.13648.38, Hamburg, Germany., Rameix-Welti MA; Université Paris-Saclay, Université de Versailles St. Quentin, UMR 1173 (2I), INSERM, Assistance Publique des Hôpitaux de Paris, Hôpital Ambroise Paré, Laboratoire de Microbiologie, Versailles, France., Empting M; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany., Fischer N; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorfgrid.13648.38, Hamburg, Germany., Hirsch AKH; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; Helmholtz International Lab for Anti-Infectives, Helmholtz Center for Infection Research, Braunschweig, Germany.; Cluster of Excellence RESIST (EXC 2155), Hanover Medical Schoolgrid.10423.34, Hanover, Germany., Schulz TF; Institute of Virology, Hanover Medical Schoolgrid.10423.34, Hanover, Germany.; German Centre for Infection Research, Hanover-Braunschweig Site, Hanover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hanover Medical Schoolgrid.10423.34, Hanover, Germany., Pietschmann T; Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany.; German Centre for Infection Research, Hanover-Braunschweig Site, Hanover, Germany.; Helmholtz International Lab for Anti-Infectives, Helmholtz Center for Infection Research, Braunschweig, Germany.; Cluster of Excellence RESIST (EXC 2155), Hanover Medical Schoolgrid.10423.34, Hanover, Germany.
Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Dec 20; Vol. 66 (12), pp. e0103222. Date of Electronic Publication: 2022 Nov 08.
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6
Akademický článek
A condensate-hardening drug blocks RSV replication in vivo.
Autor: Risso-Ballester J; Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France., Galloux M; Unité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France., Cao J; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China., Le Goffic R; Unité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France., Hontonnou F; Unité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France., Jobart-Malfait A; Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France., Desquesnes A; Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France., Sake SM; Helmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Haid S; Helmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Du M; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China., Zhang X; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China., Zhang H; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China., Wang Z; Qingdao Municipal Center for Disease Control and Prevention, Qingdao, P. R. China., Rincheval V; Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France., Zhang Y; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China., Pietschmann T; Helmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany., Eléouët JF; Unité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France. jean-francois.eleouet@inrae.fr., Rameix-Welti MA; Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France. marie-anne.rameix-welti@uvsq.fr.; Assistance Publique des Hôpitaux de Paris, Université Paris Saclay, Hôpital Ambroise Paré, Laboratoire de Microbiologie, Boulogne-Billancourt, France. marie-anne.rameix-welti@uvsq.fr., Altmeyer R; Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China. ralf.marius.altmeyer@gmail.com.; School of Public Health, University of Hong Kong, Hong Kong SAR, P. R. China. ralf.marius.altmeyer@gmail.com.
Publikováno v: Nature [Nature] 2021 Jul; Vol. 595 (7868), pp. 596-599. Date of Electronic Publication: 2021 Jul 07.
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7
Akademický článek
Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.
Autor: Blockus S; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Sake SM; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Wetzke M; Department for Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany., Grethe C; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany., Graalmann T; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany; Clinic for Immunology and Rheumatology, Hannover Medical School, Hannover, Germany., Pils M; Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany., Le Goffic R; Unité de Virologie et Immunologie Moléculaires, INRA, Université Paris Saclay, Jouy-en-Josas, France., Galloux M; Unité de Virologie et Immunologie Moléculaires, INRA, Université Paris Saclay, Jouy-en-Josas, France., Prochnow H; Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany., Rox K; Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany., Hüttel S; Department Microbial Drugs, Helmholtz Centre for Infection Research, Braunschweig, Germany., Rupcic Z; Department Microbial Drugs, Helmholtz Centre for Infection Research, Braunschweig, Germany., Wiegmann B; Lower Saxony Center for Biomedical Engineering, Implant Research and Development, Hannover Medical School, Hannover, Germany; Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany; Member of the German Centre for Lung Research (DZL), Hannover, Germany., Dijkman R; Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland; Institute for Infectious Diseases, University of Bern, Switzerland., Rameix-Welti MA; UMR1173, Institute National de la Santé et de la Recherche Médicale (INSERM), Université de Versailles St. Quentin, Montigny-le-Bretonneux, France., Eléouët JF; Unité de Virologie et Immunologie Moléculaires, INRA, Université Paris Saclay, Jouy-en-Josas, France., Duprex WP; University of Pittsburgh School of Medicine, Pittsburgh, PA, United States., Thiel V; Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland., Hansen G; Department for Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Brönstrup M; Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany., Haid S; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany. Electronic address: sibylle.haid@twincore.de., Pietschmann T; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany. Electronic address: thomas.pietschmann@twincore.de.
Publikováno v: Antiviral research [Antiviral Res] 2020 May; Vol. 177, pp. 104774. Date of Electronic Publication: 2020 Mar 18.
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8
Akademický článek
Protecting-Group-Mediated Diastereoselective Synthesis of C4'-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus.
Autor: Köllmann C; Technische Universität Braunschweig, Institute for Organic Chemistry, Hagenring 30, 38106 Braunschweig, Germany., Sake SM; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, A Joint Venture Between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Feodor-Lynen-Str. 7, 30625 Hannover, Germany., Jones PG; Technische Universität Braunschweig, Institute for Inorganic and Analytical Chemistry, Hagenring 30, 38106 Braunschweig, Germany., Pietschmann T; Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, A Joint Venture Between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Feodor-Lynen-Str. 7, 30625 Hannover, Germany., Werz DB; Technische Universität Braunschweig, Institute for Organic Chemistry, Hagenring 30, 38106 Braunschweig, Germany.
Publikováno v: The Journal of organic chemistry [J Org Chem] 2020 Mar 20; Vol. 85 (6), pp. 4267-4278. Date of Electronic Publication: 2020 Feb 26.
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