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Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

Autor: Palanivel Kandasamy, Inti Zlobec, Damian T. Nydegger, Jonai Pujol‐Giménez, Rajesh Bhardwaj, Senji Shirasawa, Toshiyuki Tsunoda, Matthias A. Hediger

Publikováno v: Molecular Oncology, Vol 15, Iss 10, Pp 2782-2800 (2021)

Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and leucine, to accelerate energy meta

Externí odkaz: https://doaj.org/article/b6fc7ae16925449f8d9d9da78bd65412

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

Autor: Kandasamy, Palanivel, Zlobec, Inti, Nydegger, Damian T., Pujol-Gimenez, Jonai, Bhardwaj, Rajesh, Shirasawa, Senji, Tsunoda, Toshiyuki, Hediger, Matthias A.

Publikováno v: Molecular Oncology, Vol 15, Iss 10, Pp 2782-2800 (2021)
Kandasamy, Palanivel; Zlobec, Inti; Nydegger, Damian T.; Pujol-Gimenez, Jonai; Bhardwaj, Rajesh; Shirasawa, Senji; Tsunoda, Toshiyuki; Hediger, Matthias A. (2021). Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1. Molecular oncology, 15(10), pp. 2782-2800. Wiley 10.1002/1878-0261.12999
Molecular Oncology

Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and leucine, to accelerate energy meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a795f42a360b9b4023eb57bc3da15e70
https://doaj.org/article/b6fc7ae16925449f8d9d9da78bd65412

HSF1 Stimulates Glutamine Transport by Super-Enhancer-Driven lncRNA LINC00857 in Colorectal Cancer.

Autor: Shen, Qi¹ (AUTHOR), Wang, Rui² (AUTHOR), Liu, Xinling² (AUTHOR), Song, Ping³ (AUTHOR), Zheng, Mingzhu² (AUTHOR), Ren, Xiaomin² (AUTHOR), Ma, Jingang² (AUTHOR), Lu, Zhong² (AUTHOR), Li, Jiaqiu² (AUTHOR) lijq@wfmc.edu.cn

Publikováno v: Cancers. Aug2022, Vol. 14 Issue 16, p3855. 18p.

Connecting the dots: investigating the link between environmental, genetic, and epigenetic influences in metabolomic alterations in oral squamous cell carcinoma.

Autor: Gupta, Ishita^1,2 (AUTHOR), Badrzadeh, Fariba^1,2 (AUTHOR), Tsentalovich, Yuri³ (AUTHOR), Gaykalova, Daria A.^1,2,4,5 (AUTHOR) dgaykalova@som.umaryland.edu

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 8/21/2024, Vol. 43 Issue 1, p1-32. 32p.